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Please enquire for more information about 2-(4-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Hydroxyisoquinoline is a heterocyclic compound that is synthesized from the reaction of acetylacetone with hydroxylated isoquinoline. It has two stereoisomers and four possible alkyl substituents. 8-Hydroxyisoquinoline can be used as a reagent for the synthesis of other compounds, such as sulfoxides, which are intermediates in organic reactions. The reaction can be carried out at room temperature and the product will precipitate from the solution due to its high solubility in water. This process is not very efficient, so it is best to use a large amount of solvent and increase the reaction time to obtain higher yields. The purity of this compound can be determined by using gel chromatography and anhydrous sodium acetate. 8-Hydroxyisoquinoline's skeleton contains a ligand group that binds to metal ions, which makes it useful for hypotensive drugs.

Applications 3-(quinolin-2-yl)propanoic acid (cas# 39111-94-9) is a useful research chemical for biological study. In particular it has been used in identifying structure-activity relationship of HDAC6 zinc-finger ubiquitin binding domain inhibitors. References Ferreira, F., et al.: J. Med. Chem, 61, 4517 (2018)

Applications Indole analogue; shows pharmacological activity. References Mohammadi, M., et al.: Science, 276, 955 (1997), Bramson, H., et al.: J. Med. Chem., 44, 4339 (2001), Lane, M., et al.: Cancer Res., 61, 6170 (2001), Yu, B., et al.: Biochem. Pharmacol., 64, 1091 (2002),

Please enquire for more information about 2-(4-Methoxyphenyl)-3-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Phenanthrenequinone is a redox potential inhibitor that binds to the catalytic site of the enzyme. It is an inhibitor with a redox potential of -0.4 V (vs Ag/AgCl). Phenanthrenequinone has been shown to be toxicologically safe in human serum and has no carcinogenic potential. The reaction mechanism is not well understood, but it may be due to hydrogen bonding interactions with the enzyme active site.

Please enquire for more information about 7-Chloro-1-ethyl-6-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

The optimal reaction conditions for the acylation of 5-bromoindole with 2,2,2-trichloroethyl chloroformate are a mixture of methanol and sodium hydroxide solution. Reaction products include 2-chloro-5-(trichloromethyl)quinoline and the quinoline derivative 1-(2,2,2-trichloroethyl)-1H-imidazole. UV absorption spectra of these products have been recorded in the range of 200 to 400 nm. The reaction is successfully monitored by following changes in the NMR spectrum. The liquid chromatography method is based on a reverse phase column and detection at 220 nm.

Applications 2-(Chloroacetyl)isoindoline was used in the reaction with potassium thiocyanate to synthesize N-​(α-​Thiocyanatoacetyl)​indolines, which is useful as agricultural fungicides. References Richter, S.: U.S. (1975), US 3929830 A 19751230.

2-Amino-1H-isoindole-1,3(2H)-dione is a reactive compound that can be prepared by the reaction of sodium salts with aniline. It is a valuable intermediate used in the synthesis of various organic compounds. The 2-Amino-1H-isoindole-1,3(2H)-dione molecule has two functional groups: sulfoxide and aziridino. This compound exhibits anticancer activity against carcinoma cell lines. It also has been shown to repair genes damaged by cancer cells and inhibit their growth.

8-Methyl-isoquinoline (8MI) is a chiral molecule that has two different enantiomers, the R and S forms. The R form is optically active and the S form is not. 8MI has been shown to have a regioselective reaction with acidic solutes in the presence of aluminum oxide. When exposed to an acidic environment, 8MI reacts in an atropisomeric fashion and forms benzyne. This reaction occurs when 8MI dissolves in water or alcohols. In addition, 8MI has been shown to have triazine properties due to its three alkyl groups on the benzene ring.

6-Nitroindazole is an antibacterial agent that inhibits the growth of bacteria by binding to bacterial DNA and blocking DNA synthesis. 6-Nitroindazole has been shown to induce tumor cell apoptosis in mouse cancer models. This drug also has anti-inflammatory properties, as it inhibits prostaglandin synthesis by inhibiting cyclooxygenase activity.

Please enquire for more information about 8-Methyl-2,8-diazaspiro[4.5]decan-3-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(2-Methoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 3-Azabicyclo[3.3.0]octane Hydrochloride is a reactant in the preparation of substituted pyrimidines derivatives as novel hedgehog signaling pathway inhibitors. References Xin, M. et al.: Med. Chem. Res., 23, 3784 (2014); Xin, M. et al.: Bioorg. Med. Chem. Lett., 24, 983 (2014);

6-Hydroxy-4-methylcoumarin is a chemical compound that serves as a lactone derivative. It is commonly derived from synthetic sources through various organic reactions involving resorcinol and ethyl acetoacetate. The compound functions primarily through its ability to absorb ultraviolet light and fluoresce, making it highly valuable in spectroscopic analyses. This compound finds extensive applications in chemical and biological research. Its fluorescent properties are exploited in the development of various assays, including enzyme activity studies and cellular imaging. Additionally, 6-hydroxy-4-methylcoumarin can be used as a starting material for synthesizing more complex coumarin-based molecules, which may serve diverse roles such as anticoagulants or other pharmaceutical agents. Researchers also explore its potential antioxidant and antimicrobial activities, contributing to the study of oxidative stress and microbial resistance mechanisms. Overall, 6-hydroxy-4-methylcoumarin is a crucial tool in scientific investigation, providing insights into molecular interactions and enabling the development of novel therapeutic compounds.

Please enquire for more information about (2-Methyl-6-oxopyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-7(6H)-yl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Oxypeucedanin hydrate acetate is a furanocoumarin, primarily classified as a phytochemical. It is derived from various plant sources, particularly from species in the Apiaceae family, such as Peucedanum and Angelica. These compounds are typically isolated through advanced extraction and chromatographic techniques. The mode of action of oxypeucedanin hydrate acetate involves the inhibition of cytochrome P450 enzymes, which play a pivotal role in the metabolism of drugs within the liver. This compound can influence the pharmacokinetics of co-administered pharmaceuticals and is thereby of significant interest to pharmacologists and toxicologists. In research, oxypeucedanin hydrate acetate has been investigated for its potential applications in cancer therapy, owing to its ability to induce apoptosis in certain cancer cell lines. Additionally, it is studied for its antimicrobial properties and its role in modulating cellular oxidative stress responses. These attributes make it a valuable subject in the exploration of new therapeutic agents and in understanding herb-drug interactions within complex biological systems.

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Please enquire for more information about 1-(2-Fluorobenzyl)-3-formyl-6-methyl-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-(2-Pyridyl)imidazole is an imidazole with two pyridine rings. It is a weak chelating agent that forms complexes with metal ions, such as copper and iron. The enthalpy of the reaction between 4-(2-pyridyl)imidazole and copper(II) ion was determined calorimetrically using a stepwise method. The enthalpy of the reaction between 4-(2-pyridyl)imidazole and iron(III) ion was determined by calorimetric studies. The structure of 4-(2-pyridyl)imidazole was confirmed by X-ray crystallography.

Please enquire for more information about 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(5-Methyl-Thiophen-2-Yl)-1H-Indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-{2-[(2-Methyl-1,2,3,4-tetrahydroquinolin-8-yl)oxy]ethyl}acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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