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Applications Bicyclo[4.1.0]Heptane-7-Carboxylic Acid (cas# 41894-76-2) is a useful reagent for the heteroatom-​directed C-​H borylation of cyclopropanes and cyclobutanes. References Murakami, R., et al.: Chem. Eur. J., 20, 13127 (2014)

7-Azaindole-5-carboxylic acid methyl ester is an ester derivative that can be synthesized from the reaction of acetyl chloride and diazotization. 7-Azaindole-5-carboxylic acid methyl ester has been used in research for its biological activity, specifically as a cytotoxic agent. It has also been shown to inhibit the growth of cancer cells by alkylation reactions and cyclization reactions. 7-Azaindole-5-carboxylic acid methyl ester has been shown to have antitumor properties with a mechanism that is not yet fully understood.

Applications methyl 8,8-dioxo-8lambda6-thia-2,3,5,7-tetraazatricyclo[7.4.0.0,2,6]trideca-1(13),3,5,9,11-pentaene-4-carboxylate (cas# 1311315-62-4) is a useful research chemical.

3-Iodoquinolin-4-ol is a synthetic compound that inhibits bacterial growth by inhibiting the synthesis of RNA and DNA. It has been shown to be active against Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis, but not against Gram-negative bacteria such as Escherichia coli. 3-Iodoquinolin-4-ol also has potentiating effects on the CFTR protein in cells with the F508del mutation. This mutation affects the chloride channel present in the cell membrane, which leads to an increased amount of salt in body fluids and can cause cystic fibrosis (CF). The terminal alkynes within this molecule are bioisosteres for amides when they are coupled to boronic acids, which were used in an assay to measure bacterial activity.

Please enquire for more information about 1-(2-Chloro-4-Fluorobenzyl)-1H-Indole-3-Carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3. References Richter, J., et al.: J. Am. Chem. Soc., 129, 12857 (2007); Yeung, B., et al.: J. Med. Chem., 53, 5155 (2010);

Please enquire for more information about 1-Benzyl-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Methyl-2-phenyl-1H-imidazole-4-carboxylic acid (MPICA) is a potent inhibitor of xanthine oxidase. It is also an inhibitor of β-glucuronidase and enzymes that maintain the integrity of bacterial DNA. MPICA has been shown to inhibit xanthine oxidase in a dose dependent manner and can be used as a lead compound for new inhibitors of this enzyme.

4-Methoxy-2,3-dihydro-1H-indole is a synthetic compound that can be prepared by bromination of 4-methoxyindole. This reaction is regioselective and the desired isomer can be obtained in good yield. Concurrent nitration and bromination reactions are investigated with the aim of obtaining an efficient method for the synthesis of 2,3-dihydrobenzo[b]indoles. The photolabile nature of the bromide group on 4-methoxy-2,3-dihydro-1H-indole makes it possible to selectively debrominate this functional group under mild conditions.

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Please enquire for more information about 7-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Butoxyphenyl)-6,8-dimethylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Bromo-5-methyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page