Heterociclos con oxígeno (O)

4,5-Dibromo-1,2,6,7-tertahydro-8H-indeno[5,4-b]furan-8-one is a chemical reagent that is used for the debromination of ethyl cyanoacetate. The nucleophilic nature of the hydroxyl group in the target compound makes it an efficient substrate for this reaction. This reagent can be used to synthesize ramelteon which is a drug approved by the U.S. Food and Drug Administration (FDA) for insomnia treatment. This high yield synthesis highlights 4,5-dibromo-1,2,6,7-tertahydro-8H-indeno[5,4b]furan-8one's usefulness as a debrominating agent.

Please enquire for more information about (3aR,4S,5R,6aS)-4-(tert-Butyldiphenylsilyloxy)methyl-5-tetrahydropyranyloxy-hexahydro-2H-cyclopenta[b]furan-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-[2-(5-Methylfuran-2-yl)vinyl]-4,6-bis(trichloromethyl)-1,3,5-triazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Chlorotetrahydrofuran is a colorless liquid with a boiling point of 33.5°C. It is soluble in carbon tetrachloride, hydrocarbons, and ethers. This compound reacts rapidly with potassium t-butoxide to form 2-chloroethyl vinyl ether (2CEVE), ethylene, and chloroform as the reaction products. The reaction can be carried out efficiently using a hydrocarbon solvent such as hexane or heptane. 2-Chlorotetrahydrofuran is an important precursor for the synthesis of pyrimidine nucleosides and other pharmaceutical compounds. It has been shown to have cytostatic activity against leukemia cells in vitro when used at high concentrations.

Stability Moisture Sensitive Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives. References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol is a polycyclic compound that has been shown to be an inhibitor of the transcriptional coactivator PPARγ. It is not active in its free form but needs to be activated by magnesium or other metal ions. It has been shown to inhibit mitochondrial membrane potential and reduce levels of PGE2. (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol inhibits the polymerase chain reaction and dna template synthesis in vitro. This substance also induces skin cancer in rats when applied topically as a cream to sunburned skin. The mechanism of this effect is not yet known but may involve interference with cellular signaling pathways.

Hexafluoro-2,5-dihydrofuran is a molecule that consists of one sulfur atom and six fluorine atoms. It has the chemical formula SF6. Hexafluoro-2,5-dihydrofuran is an oxidant with a strong oxidizing power and can be used as an oxidant in organic synthesis. It can react with sodium hypochlorite to form permettant, which is a reagent for the conversion of alcohols to alkyl chlorides. Hexafluoro-2,5-dihydrofuran reacts with oxirane to produce fluoride and hydrogen fluoride. This compound is also known as hexafluorodihydrofluorane or tetrafluoromethane.

5-Chloro-benzofuran-2-carboxylic acid ethylester is a drug that inhibits the enzyme HMG-CoA reductase, which plays an important role in the synthesis of cholesterol. It is used to lower triglyceride levels and reduce serum triglycerides. 5-Chloro-benzofuran-2-carboxylic acid ethylester has also been shown to have antilipidemic activity, as it lowers high levels of cholesterol and triglycerides. This drug is metabolized by cytochrome P450 2C8 and 2C9, which may lead to increased levels of liver enzymes.

Please enquire for more information about 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-2-chloro-6-(naphthalen-1-yl)purine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Isobenzofuran-1(3H)-one is a chemical compound that is structurally similar to the drug coumarin. Isobenzofuran-1(3H)-one has shown potential as a drug target and has been shown to have antioxidative properties, inhibitory properties and biological properties. It also has a dihedral angle of about 100°, which may be important for its biological function. Isobenzofuran-1(3H)-one inhibits the production of p-hydroxybenzoic acid by inhibiting basic fibroblast cells, which may be related to its inhibitory effect on cancer cells. This chemical compound also induces mitochondrial membrane depolarization and neuronal death in rat brain cells in vitro.

Methyl 4-oxotetrahydrofuran-3-carboxylate is a tetrahydrofuran with an acyclic structure. It has a potency of 100 µM and is selective for the human receptor. Methyl 4-oxotetrahydrofuran-3-carboxylate binds to the human receptor and activates it, leading to an increase in intracellular cAMP levels. This compound has been shown to have significant affinity for the 5HT2A receptor and can be used as a potential drug lead. Methyl 4-oxotetrahydrofuran-3-carboxylate is synthesized from 3,4,5,6,7,8-hexahydrobenzo[e]pyrrolo[1,2a]pyrazine by sulfonylation with sodium hydroxide followed by hydrolysis with sulfuric acid. The synthesis of methyl 4-ox