Heterociclos con nitrógeno (N)

Please enquire for more information about 2-Pyridin-3-yl-thiazole-4-carboxylic acid ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

3,5-Bis(aminomethyl)pyridine is a linker that connects two molecules. It can be used to construct traceless and imidazole-based derivatives. 3,5-Bis(aminomethyl)pyridine is an anionic ligand that binds to the axial position of a metal ion in coordination chemistry. It is electron donating and has affinity for reductive cleavage. The electron donating properties of 3,5-bis(aminomethyl)pyridine make it a good candidate for synthesis with electron deficient substrates. 3,5-Bis(aminomethyl)pyridine has been found to bind to β-cyclodextrin in supramolecular chemistry and can be used as an axial ligand in the construction of complex organic molecules.

Please enquire for more information about 4-Hydroxymethyl-1-methyl-2-piperidone including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Boc-3-[(dimethylamino)methylene]-4-oxopiperidine is a nasal decongestant that is used to shrink the nasal passages and relieve congestion. It is also used in postoperative care to reduce swelling in the nose and sinuses, as well as for pediatric patients with colds or allergies. 1-Boc-3-[(dimethylamino)methylene]-4-oxopiperidine has been shown to have receptor activity and may be an effective treatment for inflammatory diseases such as asthma. This compound does not dissolve in water but can be mixed with solvents for use. 1-Boc-3-[(dimethylamino)methylene]-4-oxopiperidine is inexpensively manufactured from readily available starting materials, which makes it ideal for large scale production.

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4-Acetylimidazole is a histidine analogue that has been shown to have anticancer activity in breast cancer cells. It can react with amines and form imidazoles. The hydroxyl group on the 4-position of the imidazole ring is able to undergo dehydration, which leads to the formation of a chloride ion. This reaction mechanism is reversible and can be used in organic synthesis. 4-Acetylimidazole can also act as an h2 receptor antagonist, although it does not bind to the zwitterionic site of the h2 receptor. NMR spectra show that 4-acetylimidazole exists as a zwitterion in water solution, but becomes a monovalent ion when dissolved in an organic solvent such as methanol or acetone. 4-Acetylimidazole is chemically stable and does not react with poloxamer.

1-(Methylsulfonyl)piperazine (1-MSMP) is a molecule that has been shown to have potent inhibitory activity against cancer cells. 1-MSMP is a covalent inhibitor of the 5-HT4 receptor, which may be due to its ability to form hydrogen bonds with the receptor. This drug has also been shown to induce apoptosis in prostate cancer cells and inhibit cellular proliferation in breast cancer cells, suggesting that it may be useful for treating various cancers. 1-MSMP was found to have chemoprotective effects against colitis by inhibiting the growth of inflammatory cells.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

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9-Ethylguanine is a protonated guanine derivative that has significant cytotoxicity. It is an analog of the natural nucleobase guanosine and is structurally similar to the group P2 purine base, hypoxanthine. 9-Ethylguanine specifically binds with nitrogen atoms in DNA, forming hydrogen bonds with adjacent bases. The compound has low potency and therefore must be administered at high doses for it to be effective. 9-Ethylguanine has been shown to have anticancer activity against cervical cancer cells in cell cultures, but no biological studies have been conducted on other cancer types.

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4-Hydroxypyridine-3-sulfonic acid is the anion of 4-hydroxypyridine with sulfate. It has a pK a of 1.5 and is soluble in water, ethanol, and methanol. 4-Hydroxypyridine-3-sulfonic acid can be used as a crystallographic data collection reagent. The anion can act as an acceptor for radiation and can also be used to generate hydrogen sulfate. Hydrogen sulfate is generated by the reaction of sulfuric acid with potassium hydroxide or sodium hydroxide. Hydrogen sulfate reacts with elemental sulfur to produce hydrogen sulfide. This compound has been shown to have properties that make it useful in analytical chemistry, such as its ability to form hydrogen bonds and act as an anion. The structure of 4-hydroxypyridine-3-sulfonic acid is shown below: 4 H O 2 S

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Please enquire for more information about cis-1'-Oxo-spiro[cyclohexane-1,3'(1'h)-furo[3,4-c]pyridine]-4-carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Amino-6-hydroxy-8-mercaptopurine is an antimicrobial agent that inhibits the growth of bacteria by binding to their ribosomes. It has been shown to have a cytotoxic effect in vivo on cancer cells and intestinal parasites, as well as a protective effect against infectious diseases. 2-Amino-6-hydroxy-8-mercaptopurine has also been shown to inhibit the synthesis of proteins in vitro, which may be due to its ability to bind to the ribosomal subunit and inhibit protein synthesis. 2-Amino-6-hydroxy-8-mercaptopurine inhibits bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or gluc

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5-Fluoro-2-methylpyridine is a chemical compound that can be used as an intermediate in the synthesis of pharmaceuticals. It reacts with benzoic acid to form 5-fluoro-2-methylbenzoic acid, which has been shown to have antihistamine properties. The reaction product is a constant, which is determined by the constant pressure and diameter of the reactor. 5-Fluoro-2-methylpyridine can also react with dopamine to form 5-(3,4-dihydroxyphenyl)-1H-pyrazole (DHP) and 5-(3,4,5 -trihydroxyphenyl)-1H-pyrazole (THP), both of which are biogenic amines. DHP has been shown to inhibit histamine release from mast cells and THP has been shown to inhibit the release of serotonin from platelets. Citric acid was found to induce a 1.

Applications 1-[4-Bromo-2-(1,1-dimethylethyl)phenyl]-1H-pyrrole-2,5-dione is derived from 2-(tert-Butyl)aniline (B809793), which is used as an intermediate in various reactions including towards substituted indole-2-carboxylic acids as inhibitors of bacterial metallo-beta-lactamases, which ultimately results in the potential for the use in the treatment of bacterial infection. References Brem, J.; et al.: PCT Int. Appl. 171pp. Patent 2017 CODEN:PIXXD2

2-Chloro-3-ethylpyrazine is a synthetic organic compound that is used as an analyte for gas chromatography. The 2-chloro-3-ethylpyrazine compound is not found in natural products, but can be prepared by the chlorination of 3-ethylbenzaldehyde with hydrochloric acid. It can also be synthesized from 2,4,6-trichlorophenol and ethyl nitrite. 2-Chloro-3-ethylpyrazine is used as a coating for solid phase microextraction (SPME) fibers to aid in the collection of volatile compounds from air or other gases. Gas chromatography (GC) analysis of 2-chloro-3-ethylpyrazine has been shown to be useful in the detection and identification of ethanol in samples. This artificial chemical is used as a solvent for some analytical coatings on SPME fibers, which are then used to extract volatile compounds from air

2,6-Dibromo-3,5-dimethylpyridine is a white crystalline solid. It is an organic compound that belongs to the group of heterocyclic compounds. 2,6-Dibromo-3,5-dimethylpyridine has been shown to be sensitive to nitrite and oriented in solution with respect to the fluorescence. This compound also exhibits photochromism and reacts with sodium hydroxide solution or protonation by hydroxide solution. The pyridine ring can be protonated. 2,6-Dibromo-3,5-dimethylpyridine has been used as a sensor for nitrite due to its sensitivity to this molecule.

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5-Bromo-2-iodo-3-methylpyridine is a research chemical that is used to synthesize boronic acids. It has been shown to react with aryl or alkyl boronic acids in the presence of a base to form cross-coupling products. 5-Bromo-2-iodo-3-methylpyridine can be used as an anticancer drug by reacting with chloride ions, which are toxic for cells. The 5-bromo group on the compound reacts with chloride ions, forming methylene chloride and hydrochloric acid. This product can also be used as a synthetic intermediate in the synthesis of lonafarnib, which inhibits protein prenylation and is used in cancer treatment.

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2-Isobutyl-3-methylpyrazine, also known as IBP, is a synthetic product that has been shown to have antimicrobial activity. It is produced by the bacterial species Pseudomonas syringae and inhibits the growth of Gram-positive bacteria. The biosynthesis of IBP is not well understood and it has been shown that this compound can be used as an alternative to antibiotics for food preservation. 2-Isobutyl-3-methylpyrazine has been found in cheese and beer samples. This compound has a constant boiling point at 160°C and can be detected using gas chromatography with mass spectrometric data. 2-Isobutyl-3-methylpyrazine is soluble in organic solvents such as chloroform or dichloromethane, which are generally used for solid phase microextraction (SPME). It can be classified as type strain or strain. The type strain of IBP is Pse

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Gamma-oxo-3-pyridinebutyric acid (GOBA) is a non-protein amino acid that has been shown to be involved in the development of cancer. GOBA was found to be present in urine samples from patients with liver cancer and breast cancer, as well as in healthy individuals. GOBA is also present in rat liver microsomes and human liver, where it is converted into gamma-aminobutyric acid (GABA). This conversion may be due to GOBA's hydroxy group that can be oxidized by cytochrome P450 enzymes. The biological activity of GOBA appears to depend on its carboxyl group, which can form a complex with molybdenum. This complex inhibits the activity of the protein polymerase chain reaction, leading to a decrease in transcriptional regulation. In animal experiments, GOBA has been shown to inhibit tumor growth and induce cell cycle arrest by inhibiting the expression of cyclin D1 at the

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Intermediate in the synthesis of tofacitinib

Stability Hygroscopic Applications 2-Aminopyrimidine-5-boronic acid

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Please enquire for more information about N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamideHydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(Dimethylvinylsilyl)pyridine is an organic solvent that is soluble in most solvents. It has been used as a coupling agent, and can be prepared by the reaction of ethylene with 2-chloropyridine. The nucleophilic nature of this compound makes it a strong nucleophile.

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Trans-1'-((4-(Fluoro-18F)phenyl)methyl)-4-phenyl-(1,3'-bipiperidin)-4'-ol is a radioactive diagnostic agent that is used to visualize the pancreas. It binds to cholinergic receptors and emits positron emission tomography (PET) signals that are detectable by a PET scanner. Trans-1'-((4-(Fluoro-18F)phenyl)methyl)-4-phenyl-(1,3'-bipiperidin)-4'-ol has been shown to be safe in humans, with no evidence of adverse effects on cell function or amines. This compound has also been shown to have an uptake in the pancreas and exocrine glands.

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3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine is a synthetic compound that is used as an intermediate in the synthesis of various chemicals, including pharmaceuticals. It has been shown that 3-chloro-2-fluoro-5-(trifluoromethyl)pyridine can be successfully removed from wastewater using a palladium catalyst and boronic acid. The reaction time required to achieve complete conversion of the chemical is less than 1 hour. Impurities and chlorides are present in this chemical, although they have no effect on its reactivity.

1-Cbz-2-Piperidinecarboxaldehyde is a fluorescent probe that can be used to detect the presence of copper ions in solution. It has been shown to react with copper ions by undergoing a ring-opening reaction with the hydrazone bond. The fluorescence intensity increases as the concentration of copper ions increases. The labeling reaction between 1-Cbz-2-Piperidinecarboxaldehyde and copper ions can be detected using fluorescence imaging techniques and colorimetric assays. 1-Cbz-2-Piperidinecarboxaldehyde is also able to bind to caco-2 cells, which are cells from the human colon that can be used in experiments related to drug absorption and distribution.

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2-(2H-Tetrazol-5-yl)pyridine (2HTZP) is a copper complex that is used as ancillary ligands in coordination chemistry. The nitrogen atoms are coordinated to the copper atoms, and the luminescent probe can be attached to the oxadiazole ring. 2HTZP has been used to study the structure of oxadiazole and picolinic acid in solution and in solid state, as well as fatty acids. 2HTZP has also been used for immobilization of metal ions on silica gels, where it served as a substrate for x-ray crystal structures. In addition, 2HTZP has been shown to have photophysical properties that allow it to be used as a sensor for picolinic acid and fatty acids.

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