Heterociclos con nitrógeno (N)

Please enquire for more information about 1-(Ethylsulfonyl)piperidine-3-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Ethylaminopyrimidine-5-boronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Chloro-2-piperazin-1-yl-1,3-benzoxazole dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (Z)-Ethyl 2-(piperidin-3-ylidene)acetate hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (4,4,6-Trimethyl-1,4-dihydropyrimidin-2-yl)cyanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Bromo-2-methoxy-3-nitropyridine is a potent inhibitor of phosphoinositide 3-kinase (PI3K) that has tumor growth inhibition activity. It is also an inhibitor of cellular activities, such as cell proliferation and cell migration. 5-Bromo-2-methoxy-3-nitropyridine inhibits the activation of mammalian PI3K, which is necessary for the production of phosphatidylinositol phosphate (PIP) in cells. This drug also exhibits anti-tumor activity in hepatocellular carcinoma and other cancers with PI3K activation. 5Bromo2 methoxy 3 nitropyridine binds to the active site of mammalian PI3K and blocks the production of PIP, leading to tumor growth inhibition.

Please enquire for more information about 8-Aminoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2,4-DIHYDRO-[1,2,4]TRIAZOLE-3-THIONE (cas# 3179-31-5) is a useful research chemical.

Applications 4-Chloro-2-(trifluoromethoxy)pyrimidine (cas# 1261494-46-5) is a compound useful in organic synthesis.

2,4,6-Triaminopyrimidine is an organic compound that can be found in a variety of sources. It is used as a research chemical and has shown to have anti-inflammatory properties in the rat kidney. This compound has been shown to bind with nucleobases and form hydrogen bonds with glycosidic bonds. 2,4,6-Triaminopyrimidine has also been shown to be a ligand for affinity chromatography.

Please enquire for more information about {3-Chloro-4-[4-(4-propoxybenzoyl)piperazin-1-yl]phenyl}amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

3,6-Dichloro-2-methylpyridine is an organic compound that is a precursor to other compounds. It can be synthesized by the reaction of dichloromethyl chloride and acetone. 3,6-Dichloro-2-methylpyridine is used as an intermediate in the production of herbicides and as an inhibitor in nitrification processes. It has been shown to inhibit cyclization reactions.

Please enquire for more information about 4-Chloro-6-hydrazinopyrimidin-2-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,4,5,6-Tetrahydro-5,6-dioxo-2,3-pyrazinedicarbonitrile (1) is a bifunctional ligand that can be used for the preparation of coordination compounds. It is a solid with a melting point of 153°C and a boiling point of 432°C at atmospheric pressure. 1 has been shown to form hydrogen bonding interactions with hydrogen and carbon atoms in the crystal structure analyses. 1 also exhibits magnetic properties due to its high spin state. The dehydration reactions are slow because of the strong hydrogen bonding interactions between adjacent water molecules. This compound can be used as an indicator for dehydrated conditions because it changes from blue to pink when dehydrated.

2,6-Dimethoxypyridine-3-boronic acid is a boronic acid that can be used in cross-coupling reactions. In this process, an organic compound reacts with a metal to produce a new organic compound. The pyridine ring of 2,6-dimethoxypyridine-3-boronic acid is shown in the X-ray crystal structure of the molecule. This molecule has two different isomers which are 2,6-dimethoxypyridine and 3,5-dimethoxypyridine. The orientation of these isomers can be systematically changed by rotating the molecule about its central carbon atom. These changes affect the photophysical properties of this molecule. The trimethylated derivative of 2,6-dimethoxypyridine-3-boronic acid has been synthesized and found to have efficient emissions when excited with light at wavelengths between 400 and 470 nm.

Please enquire for more information about [2-Methyl-1-(piperidin-1-ylcarbonyl)propyl]amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Intermediate in the production of Methotrexate References Chiosis, G., et al.: Bioorg. Med. Chem., 10, 3555 (2002), Palanki, M., et al.: J. Med. Chem., 50, 4279 (2007), Zav'yalov, S., et al.: Pharm. Chem. J., 42, 51 (2008),

Applications 2,3-dihydro-8-(boronic acid)-1,4-Dioxino[2,3-b]pyridine-d4 is labelled 2,3-dihydro-8-(boronic acid)-1,4-Dioxino[2,3-b]pyridine (D448690) which is a derivative of 2,3-dihydro-1,4-Dioxino[2,3-b]pyridine. 2,3-dihydro-1,4-Dioxino[2,3-b]pyridine is used to prepare benzanilide derivatives for use as anticancer agents.

1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid (3CFP) is a phenoxy carboxamide that is an anticonvulsant. 3CFP has been shown to be effective in animal models of seizure and has a potency that exceeds that of phenobarbital. It also has potent anticonvulsant activity against seizures induced by pentylenetetrazole and electroshock. 3CFP binds to the GABA receptor, which is important for the regulation of neuronal excitability and is the target for many types of antiepileptic drugs. The chlorine atom in 3CFP may contribute to its pharmacological properties because it can form a covalent bond with amino acids like cysteine, which are important for protein synthesis.

Please enquire for more information about Potassium (4-Boc-piperazin-1-yl)methyltrifluoroborate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl4-methylpiperidine-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Bromo-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-(3-Chloro-4-fluorobenzoyl)-4-fluoro-N-[(5-methyl-2-pyridinyl)methyl]-4-piperidinemethanamine is a psychoactive drug with serotonergic properties that has been shown to have analgesic, anti-inflammatory, and antiallodynic effects. It has been used in the treatment of chronic cough and carcinoid syndrome. This compound binds to the 5HT7 receptor and inhibits serotonin release by binding to monoamine neurotransmitters such as dopamine, norepinephrine, and histamine. 1-(3-Chloro-4-fluorobenzoyl)-4-fluoro-N-[(5-methylpyridinyl)methyl]-4piperidinemethanamine also has been shown to have pharmacological effects on models of pain and locomotor activity.

Please enquire for more information about 3-Piperidin-1-ylbenzonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(2-Methoxyethoxy)pyridine-3-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (R)-2-Formyl-piperidine-1-carboxylic acid tert-butylester including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-Acetyl-3-hydroxyindole is a colorless liquid that inhibits the activity of enzymes such as butyric acid, active methylene, and acyl halides. It is also used to inhibit the enzyme eosinophil peroxidase in clinical tests. N-Acetyl-3-hydroxyindole has been shown to be an efficient method for high-throughput analysis of enzymatic reactions. This chemical can be immobilized on porous supports and used to measure enzyme activities. N-Acetyl-3-hydroxyindole has been shown to have therapeutic effects in clinical data with a potent inhibitor of eosinophil peroxidase.

Applications 6-Bromo-8-cyclopentyl-5-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one is used as a reactant in the preparation of pyrido[2,3-d]pyrimidin-7-one derivatives as selective inhibitors of cyclin-dependent kinases 4 and 6. References VanderWel, S., et al.: J. Med. Chem., 48, 2371 (2005); Toogood, P., et al.: J. Med. Chem., 48, 2388 (2005);

4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine is a low-potency, selective inhibitor of cytochrome P450 (CYP). It has been shown to inhibit p450 activity in rat and human liver microsomes. 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine is also a neuroprotectant that restores mitochondrial function and protects against the degenerative effects of dopamine. This drug decreases locomotor activity in rats and has been used as an anthelmintic drug. 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine is metabolized by CYP enzymes and may have other pharmacological activities due to its ability to inhibit CYPs.

Please enquire for more information about 1-(2-Chloropropanoyl)-4-(2-fluorophenyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(Propan-2-yloxy)piperidine HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Amino-2,6-dichloropyridine is a carboxamidopyridine that is used as an antiplatelet agent. This drug inhibits the action of ADP and thrombin in platelets, thereby inhibiting platelet aggregation. 3-Amino-2,6-dichloropyridine has been shown to be effective when given orally and is not degraded by stomach acid. It has been shown to inhibit transcriptase activity in vitro. The drug also inhibits the synthesis of prostaglandin E2 (PGE2) through inhibition of cyclooxygenase (COX) enzymes and prevents platelet aggregation by suppressing the production of adenosine diphosphate (ADP).

Please enquire for more information about N,N,N'-Trimethyl-N'-piperidin-4-ylpropane-1,3-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page