Building Blocks de hidrocarburos

n-Dodecane is used as a solvent and a distillation chaser. It finds application as a diluent for tributyl phosphate (TBP) in reprocessing plants and as a possible surrogate for kerosene-based fuels in jet. It is an active component of scintillator as well as used in lubricants and greases. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-Amino-1-butanol is a natural compound that is not toxic to humans. It is amide with a hydrophilic interaction chromatography property, and has been shown to have hemolytic activity against human erythrocytes. 4-Amino-1-butanol has been shown to be an inhibitor of the HIV virus, with minimal toxicity. It has also been shown to inhibit the replication of the wild type virus in cells in vitro and in vivo, which is due to its ability to bind with the enzyme ethylene diamine. The inhibition of this enzyme leads to a reduction in biological activity of amines.

3,3'-Diindolylmethane, also known as DIM, is natural compound derived from indole. In a recent study, DIM was evaluated as a potential agent for preventing biofilm formation by Streptococcus mutans, which is a major cause of dental caries. The researchers found that DIM significantly inhibited biofilm formation (by 92%) and reduced the production of extracellular polymeric substances (EPS), which are important for biofilm stability particularly under acidic conditions. The study suggests that 3,3'-diindolylmethane has anti-biofilm and anti-virulence properties against S. mutans, and it is a potential candidate for reducing biofilm formation and preventing dental caries. It has been also reported that 3,3'-diindolymethane can act as a chemopreventive agent. DIM has estrogenic effects without interacting with the binding domain of the estrogen receptors. This study found that DIM could suppress cell growth and disrupt cell cycle progression of young adult mouse colonocytes (YAMCs) in vitro. Moreover, DIM altered gene expression associated with apoptosis and cell proliferation, and it induced transcriptional activity of the estrogen receptor (ER), which was inhibited by an ER antagonist.