Amidas

4-Fluorophenylacetic acid is a synthetic organic compound that has been used as a model system for the study of the reaction between hydrogen sulfate and hydrogen. 4-Fluorophenylacetic acid is a fluorinated analog of acetamide, which can be synthesized from sodium borohydride and hydrogen fluoride. It has been shown to inhibit the growth of Mycobacterium tuberculosis in an on-line assay and is also active against Mycobacterium avium complex. 4-Fluorophenylacetic acid also inhibits rat liver microsomes with a second order rate constant of 0.0006 M−1 s−1 at pH 7.4 and 37 °C (pH and temperature not specified). The biological properties of 4-fluorophenylacetic acid are not well understood, but it may bind to hydrophobic regions on proteins or DNA through hydrogen bonding interactions.

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2-Cyano-N-(2,6-dimethylphenyl)acetamide (2CDA) is a synthetic organic compound that has been used as an intermediate in the synthesis of other compounds. It is most commonly encountered as the chloride salt, and has no known biological activity. 2CDA is soluble in water and reacts with acids to form iminium ions. It is a weak base that reacts with strong acids to form salts such as chlorides, sulfates, and iminium ions. 2CDA also reacts with alcohols to form ethers and can be used to synthesize oximes from nitroalkanes.