Antiparasitarios
Los antiparasitarios son compuestos diseñados para tratar y prevenir infecciones parasitarias mediante la inhibición del crecimiento y la supervivencia de los parásitos. Esta categoría incluye una variedad de agentes antiparasitarios destinados exclusivamente para uso en laboratorio y no para el consumo humano. Estos productos son esenciales para fines de investigación, permitiendo a los científicos estudiar los ciclos de vida de los parásitos, los mecanismos de acción y el desarrollo de resistencia. El uso de antiparasitarios en entornos de laboratorio ayuda en el descubrimiento y la optimización de nuevos tratamientos para enfermedades parasitarias, contribuyendo a los avances en parasitología médica y veterinaria. Los investigadores dependen de estos productos para mejorar su comprensión de las infecciones parasitarias y desarrollar terapias más efectivas.
Productos de "Antiparasitarios"
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DHFR-IN-20
DHFR-IN-20 (Compound LA1) is an inhibitor of dihydrofolate reductase (DHFR) targeting the malignant strains of the malaria parasite. It exhibits inhibition constants (Kis) of 0.16 nM, 0.30 nM, and 6.6 nM for PfDHFR-WT, PfDHFR-QM, and HsDHFR, respectively. Additionally, DHFR-IN-20 demonstrates antimalarial activity, with IC50 values of 1.4 nM against parasites carrying the wild-type (TM4/8.2) PfDHFR enzyme and 1.6 μM against those with the quadruple mutation (V1/S)PfDHFR.Forma y color:Odour SolidBenzeneacetonitrile, 2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-
CAS:Fórmula:C17H9Cl3N4O2Pureza:98%Forma y color:SolidPeso molecular:407.637967-Chloro-3-iodo Hydroxychloroquine
CAS:Producto controladoFórmula:C18H25ClIN3OForma y color:NeatPeso molecular:461.77DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Fórmula:C8H7BrN4Pureza:99.59% - 99.61%Forma y color:SolidPeso molecular:239.07LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Fórmula:C22H15N7Forma y color:SolidPeso molecular:377.40Antileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.Fórmula:C22H18N4O3Pureza:98%Forma y color:SolidPeso molecular:386.4DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Fórmula:C21H24Cl2N6O2SPureza:97.8% - 99.76%Forma y color:SolidPeso molecular:495.43Ref: TM-T27135
1mg96,00€5mg279,00€10mg420,00€25mg682,00€50mg947,00€100mg1.301,00€200mg1.738,00€1mL*10mM (DMSO)305,00€Primaquine diphosphate
CAS:Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties.Fórmula:C15H21N3O·2H3PO4Pureza:98.06% - 99.73%Forma y color:Orange PowderPeso molecular:455.34Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Fórmula:C17H16F6N2OPureza:99.97%Forma y color:SolidPeso molecular:378.31Ref: TM-T0860L
1mg70,00€5mg154,00€10mg225,00€25mg376,00€50mg538,00€100mg755,00€200mg1.017,00€1mL*10mM (DMSO)160,00€3-Chloro-N-(3-methoxyphenyl)propanamide
CAS:Producto controladoApplications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs. References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);Fórmula:C10H12ClNO2Forma y color:NeatPeso molecular:213.66Niclosamide
CAS:Fórmula:C13H8Cl2N2O4Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:327.12Metronidazole acetic acid
CAS:Metronidazole acetic acid, a mutagenic metabolite of an antibiotic, targets protozoa and anaerobic bacteria.Fórmula:C6H7N3O4Pureza:98%Forma y color:SolidPeso molecular:185.1375Didesethyl Chloroquine Hydroxyacetamide
CAS:Producto controladoApplications An intermediate in the preparation of Cletoquine Oxalate It is a COVID19-related research product.Fórmula:C16H20ClN3O2Forma y color:NeatPeso molecular:321.80SDZ285428
CAS:SDZ285428 is a CYP24A1 inhibitor.Fórmula:C24H20ClN3OPureza:97.51%Forma y color:SolidPeso molecular:401.89Ref: TM-T4188
2mg37,00€5mg52,00€10mg90,00€25mg170,00€50mg255,00€100mg375,00€200mg533,00€1mL*10mM (DMSO)58,00€1-Piperazinecarboxamide, N,N-diethyl-4-methyl-
CAS:Fórmula:C10H21N3OPureza:97%Forma y color:SolidPeso molecular:199.29324000000003Rafoxanide
CAS:Anthelmintic; anti-parasiticFórmula:C19H11Cl2I2NO3Pureza:Min. 95%Forma y color:PowderPeso molecular:626.01 g/molMorantel tartrate
CAS:Morantel tartrate (CP-12009-18 tartrate) is an antinematodal agent used mainly for livestock.Fórmula:C16H22N2O6SPureza:99.86%Forma y color:White Or Pale Yellow Crystalline PowderPeso molecular:370.42Modoflaner
CAS:Modoflaner is an antiparasitic (veterinary use).Fórmula:C23H10F12IN3O2Pureza:98.4%Forma y color:SolidPeso molecular:715.232-Methyl-5-nitroimidazole-1-ethanol
CAS:Fórmula:C6H9N3O3Pureza:>99.0%(GC)(T)Forma y color:White to Orange to Green powder to crystalPeso molecular:171.161H-Imidazole-1-ethanol, α-(chloromethyl)-2-methyl-5-nitro-
CAS:Fórmula:C7H10ClN3O3Pureza:98%Forma y color:SolidPeso molecular:219.6256Rafoxanide
CAS:Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.Fórmula:C19H11Cl2I2NO3Pureza:99.47%Forma y color:Slight Yellowish Brown Injectable Solution &White Oral SolutionPeso molecular:626.0113,21-Dihydroeurycomanone
CAS:13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as PlasmodiumFórmula:C20H26O9Pureza:98.01%Forma y color:SolidPeso molecular:410.42Benzoic acid, 4-(acetylamino)-2-ethoxy-, methyl ester
CAS:Fórmula:C12H15NO4Pureza:98%Forma y color:SolidPeso molecular:237.2518Paromomycin Sulfate
CAS:Paromomycin Sulfate, an aminoglycoside antibiotic, binds to 30S ribosomes, disrupting protein synthesis and killing bacteria.Fórmula:C23H47N5O18SPureza:99.73% - 99.86%Forma y color:SolidPeso molecular:713.71Diethylcarbamazine citrate
CAS:Fórmula:C16H29N3O8Pureza:98%Forma y color:SolidPeso molecular:391.4168Notrilobolide
CAS:Notrilobolide, an alkaloid with insecticidal properties, is isolated from sweet potatoes and impedes larval development in pests such as Tribolium castaneum.Fórmula:C26H36O10Pureza:98%Forma y color:SolidPeso molecular:508.56Cycloguanil Hydrochloride
CAS:Fórmula:C11H14ClN5·HClPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:288.18Ornidazole
CAS:Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections.Fórmula:C7H10ClN3O3Pureza:99.47%Forma y color:Crystalline SolidPeso molecular:219.63Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Fórmula:C20H19NO3Pureza:99.87%Forma y color:Solid CompactPeso molecular:321.37Antitrypanosomal agent 17
Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].Pureza:98%Forma y color:Odour Solid5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole
CAS:3-Br-isoxazoline-based inhibitor for Plasmodium and Leishmania; IC50: 0.035-7.5 μM.Fórmula:C15H16BrN3O2Pureza:99.58%Forma y color:SolidPeso molecular:350.21Ref: TM-T9858
1mg77,00€5mg155,00€10mg220,00€25mg338,00€50mg472,00€100mg632,00€200mg853,00€1mL*10mM (DMSO)160,00€(2E)-5-Hydroxy-2-pentenoic Acid Methyl Ester
CAS:Producto controladoFórmula:C6H10O3Forma y color:NeatPeso molecular:130.14AP-C5
CAS:AP-C5 inhibits cGKII with a Pic50 of 7.2, useful in diarrheal disease research.Fórmula:C16H13N5Pureza:99.19%Forma y color:SolidPeso molecular:275.31N-(2-Hydroxypropyl)methacrylamide
CAS:N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.Fórmula:C7H13NO2Pureza:98.84%Forma y color:SolidPeso molecular:143.18Oxibendazole
CAS:Fórmula:C12H15N3O3Pureza:>98.0%(HPLC)(N)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:249.27Antimalarial agent 29
CAS:Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.Fórmula:C18H10ClF3N2Pureza:98%Forma y color:SolidPeso molecular:346.73YCN47284
CAS:YCN47284 is an antimalarial compound with an IC50 of 1 μM for P. falciparum.Fórmula:C10H16Cl2N8Pureza:99.52%Forma y color:SolidPeso molecular:319.19Ref: TM-T9591
1mg35,00€5mg64,00€10mg104,00€25mg182,00€50mg284,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)90,00€Dodecamethylpentasiloxane
CAS:Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.Fórmula:C12H36O4Si5Pureza:97.62%Forma y color:SolidPeso molecular:384.84Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Forma y color:SolidPeso molecular:387.857Chloroquine diphosphate
CAS:Producto controladoChloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Chloroquine i a schizonticidal agent and is a widely prescribed antimalarial compound. The antiviral activity of chloroquine in vitro has been reported in 1960’s and recent publications have brought attention to its possible benefits in the treatment of COVID-19 patients, infected with the newly emerged coronavirus (SARS-CoV-2). Current evidence shows that chloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the S-glycoprotein.Fórmula:C18H32ClN3O8P2Forma y color:White Off-White PowderPeso molecular:515.86 g/molAntimalarial agent 33
Antimalarial agent 33 (compound 5g) exhibits antiplasmodial activity targeting both erythrocytic and hepatic stages of Plasmodium, with an effectivePureza:98%Forma y color:Odour SolidTafenoquine
CAS:Tafenoquine (WR 238605) is an antimalarial prophylactic agent with schizonticidal activity, useful in hemolytic anemia research.Fórmula:C24H28F3N3O3Pureza:99.56%Forma y color:SolidPeso molecular:463.49Insecticidal agent 6
CAS:Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.Fórmula:C19H14BrCl2N5O4Pureza:98%Forma y color:SolidPeso molecular:527.16Tetramisole Hydrochloride
CAS:Fórmula:C11H12N2S·HClPureza:>98.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:240.75Cordysinin C/D
CAS:Cordysinin C/D (compound 9) is a potential antimalarial agent that effectively inhibits the Plasmodium falciparum 3D7 strain.Fórmula:C13H12N2OForma y color:SolidPeso molecular:212.25Mebendazole
CAS:Mebendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating intestinal worm infections like threadworms and roundworms.Fórmula:C16H13N3O3Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:295.29 g/molMiransertib
CAS:Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.Fórmula:C27H24N6Pureza:98.83% - ≥95%Forma y color:SolidPeso molecular:432.52Ref: TM-T3467
1mg52,00€5mg97,00€10mg169,00€25mg344,00€50mg567,00€100mg908,00€500mg1.795,00€1mL*10mM (DMSO)114,00€
