Beta-bloqueante
Los betabloqueantes, también conocidos como agentes bloqueadores beta-adrenérgicos, son compuestos que bloquean la acción de la epinefrina (adrenalina) en los receptores beta, lo que reduce la frecuencia cardíaca y la presión arterial. A menudo se utilizan para tratar afecciones como la hipertensión, las arritmias y la insuficiencia cardíaca. En CymitQuimica, ofrecemos una variedad de betabloqueantes para fines de investigación en estudios cardiovasculares y clínicos.
Subcategorías de "Beta-bloqueante"
Productos de "Beta-bloqueante"
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Carvedilol EP Impurity B (Carvedilol USP Related Compound B) (Mixture of Diastereomers)
CAS:Fórmula:C39H39N3O6Forma y color:White To Off-White SolidPeso molecular:645.76Hydrochlorothiazide Dimer
CAS:Impurity Hydrochlorothiazide EP Impurity C Applications N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide (Hydrochlorothiazide EP Impurity C) is an impurity in bulk Hydrochlorothiazide. Dimer Impurity C. References Daniels, S.L., et al.: J. Pharm. Sci., 70, 211 (1981), Fang, X., et al.: Pharm. Res., 14, 691 (1997),Fórmula:C15H16Cl2N6O8S4Forma y color:Off-WhitePeso molecular:607.495-Nitrosopyrimidine-2,4,6-triamine (Nitrosotriaminopyrimidine)
CAS:Producto controladoFórmula:C4H6N6OForma y color:NeatPeso molecular:154.13Carvedilol USP Related Compound D
CAS:Fórmula:C15H13NO2Forma y color:Pale Brown SolidPeso molecular:239.27Desfluoro Nebivolol (Mixture of Diastereomers)
CAS:Fórmula:C22H26FNO4Forma y color:White To Off-White SolidPeso molecular:387.45Nebivolol Impurity 15 HCl (Mixture of Diastereomers)
CAS:Fórmula:C29H31F2NO4·HClForma y color:White To Off-White SolidPeso molecular:495.57 36.462-[[2-[[(4RS)-4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl]methoxy]ethyl]carbamoyl]benzoic Acid
CAS:Producto controladoFórmula:C28H29ClN2O8Forma y color:NeatPeso molecular:556.99Lovastatin-d9 (Mixture of Diastereomers)
CAS:Producto controladoApplications Lovastatin-d9, is the labeled analogue of Lovastatin (L472225), an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase. References Bilheimer, D.W., et al.: Proc. Nat. Acad. Sci. USA, 80, 4124 (1983),Fórmula:C24H27D9O5Forma y color:NeatPeso molecular:413.6N,N'-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethylpropane-1,3-diamine Dihydrochloride
CAS:Producto controladoForma y color:Neat1-[4-(2-Methoxyethyl)phenoxy]-2,3-epoxypropane
CAS:Producto controladoFórmula:C12H16O3Forma y color:NeatPeso molecular:208.25Ezetimibe Tetrahydropyran Impurity
CAS:Impurity Ezetimibe Tetrahydropyran Impurity Applications Ezetimibe (E975000) tetrahydropyran impurity.Fórmula:C24H21F2NO3Forma y color:White To Off-WhitePeso molecular:409.43Ethyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
CAS:Producto controladoFórmula:C18H17Cl2NO4Forma y color:NeatPeso molecular:382.24cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5
CAS:Producto controladoApplications cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5 is an isotopic analog of cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester is an ethyl analog of cis-7,10,13,16-Docosatetraenoic Acid (D494510). cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies. References Mirnikjoo, B. et al.: J. Biol. Chem., 276, 10888 (2001);Fórmula:C24D5H35O2Forma y color:NeatPeso molecular:365.604p-Torasemide (1-(1-Methylethyl)-3-[[4-[(4-methylphenyl)amino]pyridin-3-yl]sulfonyl]urea)
CAS:Fórmula:C16H20N4O3SAlthiazide
CAS:Applications Diuretic and antihypertensive. References Twagirumukiza, M., et al.: Trop. Med. Int. Health, 15, 350 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Peters, R., et al.: Anal. Bioanal. Chem., 396, 2583 (2010),Fórmula:C11H14ClN3O4S3Forma y color:NeatPeso molecular:383.895-[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]-3-(1-methylethyl)-2-oxazolidinone
CAS:Producto controladoForma y color:NeatCaptopril Methyl Ester
CAS:Producto controladoFórmula:C10H17NO3SForma y color:NeatPeso molecular:231.314’-Hydroxyphenyl Carvedilol
CAS:Producto controladoApplications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension. References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),Fórmula:C24H26N2O5Forma y color:Off White SolidPeso molecular:422.47Fluocinolone Acetonide-21-aldehyde
CAS:Impurity Fluocinolone Acetonide EP Impurity D Stability Hygroscopic Applications Fluocinolone acetonide-21-aldehyde, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching. References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),Fórmula:C24H28F2O6Forma y color:White To Light YellowPeso molecular:450.47Deiodo Amiodarone
CAS:Producto controladoImpurity Amiodarone EP Impurity C /Amiodarone USP Related Compound C Applications An intermediate of Amiodarone (A632950). Amiodarone EP Impurity C References Weir, S., et al.: J. Pharm. Sci., 74, 460 (1985), Ramanathan, R., et al.: Anal. Chem., 72, 1352 (2000),Fórmula:C25H30INO3Forma y color:NeatPeso molecular:519.415Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Fórmula:C16H25NO4·HClPureza:98.72% - 99.48%Forma y color:White SolidPeso molecular:331.15Bezafibrate 100 µg/mL in Acetonitrile
CAS:Producto controladoFórmula:C19H20ClNO4Forma y color:Single SolutionPeso molecular:361.82Carvedilol Impurity 12
CAS:Fórmula:C33H36N2O6Forma y color:White To Off-White SolidPeso molecular:556.66Hydroxyatenolol-d7
CAS:Producto controladoApplications Hydroxyatenolol-d7 is the isotope labelled analog of Hydroxyatenolol (H802480); a metabolite of Atenolol (A790075) which is a cardioselective β-adrenergic blocker, antihypertensive, antianginal, and antiarrhythmic (class II). References Escher, B., et al.: Environ. Sci. Technol., 40, 7402 (2006); Caplar, V., et al.: Anal. Profiles Drug Subs., 13, 1 (1984)Fórmula:C14H15D7N2O4Forma y color:NeatPeso molecular:289.38Simvastatin-d6
CAS:Producto controladoStability Hygroscopic Applications Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),Fórmula:C25H32D6O5Forma y color:White To Off-WhitePeso molecular:424.6Nebivolol Impurity 21 (Mixture of Diastereomers)
CAS:Fórmula:C11H11FO2Forma y color:Colorless LiquidPeso molecular:194.21Desmethyl Ranolazine-d5
CAS:Producto controladoApplications A labelled metabolite of Ranolazine (R122500). References Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004), McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998), Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002),Fórmula:C23H26D5N3O4Forma y color:NeatPeso molecular:418.54Hexobendine Dihydrochloride
CAS:Producto controladoApplications Hexobendine is used as vasodilator (coronary). References Rdudolph, et al.: Arzneim.-Forsch., 20, 637 (1970), Kolassa, P., et al.: Biochem. Pharmacol., 20, 490 (1971), Zommer-Urbanska, S., et al.: Pharmazie, 40, 419 (1985),Fórmula:C30H44N2O10·2ClHForma y color:NeatPeso molecular:665.60Betamethasone 100 µg/mL in Acetonitrile
CAS:Fórmula:C22H29FO5Forma y color:Single SolutionPeso molecular:392.466-Methyl Pergolide
CAS:Producto controladoApplications 6-Methyl Pergolide is a potent antagonist of 5-HT2A and 5-HT2B receptors on porcine cardiac valves, it also activates brain dopaminergic receptors and lowers cranial DOPAC levels in rats (1,2). References (1) Fuller, R.W., et al.: Neuroendocrinol., 36, 285 (1983)(2) Goernemann, T., et al.: J. Pharmacol. Exp. Ther., 324, 1136 (2008)Fórmula:C17H22N2SForma y color:NeatPeso molecular:286.43N-Nitroso Nebivolol
CAS:Fórmula:C22H24F2N2O5Forma y color:White To Off-White SolidPeso molecular:434.445-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
CAS:Producto controladoApplications 5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide is a photodegradation product of Atorvastatin (A791750). References Cermola, F., et al.: Tetrahedron., 62, 7390 (2006);Fórmula:C33H33FN2O5Forma y color:NeatPeso molecular:556.62Metoprolol EP Impurity O-d7 HCl (Metoprolol USP Related Compound D-d7) (Mixture of Diastereomers)
CAS:Fórmula:C27H34D7NO6·HClPeso molecular:482.67 36.46Propranolol-d7 (Naphthalenyl-d7)
CAS:Fórmula:C16H14D7NO2Forma y color:White To Off-White SolidPeso molecular:266.39
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