
Beta-bloqueante
Los betabloqueantes, también conocidos como agentes bloqueadores beta-adrenérgicos, son compuestos que bloquean la acción de la epinefrina (adrenalina) en los receptores beta, lo que reduce la frecuencia cardíaca y la presión arterial. A menudo se utilizan para tratar afecciones como la hipertensión, las arritmias y la insuficiencia cardíaca. En CymitQuimica, ofrecemos una variedad de betabloqueantes para fines de investigación en estudios cardiovasculares y clínicos.
Subcategorías de "Beta-bloqueante"
Productos de "Beta-bloqueante"
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Carvedilol Impurity 9 HCl
CAS:Fórmula:C12H11NO·HClForma y color:Off-White SolidPeso molecular:185.23 36.46Ajmaline
CAS:Producto controladoApplications An antiarrhythmic agent isolated from Rauwolfia serpentina. References Galarreta, B., et al.: Bioorg. Med. Chem., 16, 6689 (2008), Sun, L., et al.: Plant Mol. Biol., 67, 455 (2008), Ruiz-May, E., et al.: Mol. Biotechnol., 41, 278 (2009),Fórmula:C20H26N2O2Forma y color:WhitePeso molecular:326.43Carvedilol EP Impurity C
CAS:Fórmula:C31H32N2O4Forma y color:White To Off-White SolidPeso molecular:496.61Folic Acid-d4
CAS:Producto controladoApplications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),Fórmula:C192H4H15N7O6Forma y color:NeatPeso molecular:445.42Fenofibric-d6 Acid
CAS:Producto controladoApplications Labelled Fenofibric Acid (F248652). Fenofibric acid is the active metabolite of Fenofibrate (F248640). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Barter, P.J.: Arterioscler. Thromb. Vasc. Biol., 25, 1095 (2005)Fórmula:C17D6H9ClO4Forma y color:Off-WhitePeso molecular:324.794-Hydroxyphenylacetic Acid
CAS:Producto controladoFórmula:C8H8O3Forma y color:NeatPeso molecular:152.15o-Torasemide (1-(1-Methylethyl)-3-[[4-[(2-methylphenyl)amino]pyridin-3-yl]sulfonyl]urea)
CAS:Forma y color:Neat(1S,4R)-4,6-Dihydroxy-1-(hydroxymethyl)-N-methyl-1,2,3,4-tetrahydroisoquinoline
CAS:Fórmula:C11H15NO32-Isopropoxyethyl 4-[[(2RS)-2-Hydroxy-3-(isopropylamino)propyl]oxy]benzoate (Bisoprolol Ester)
CAS:Producto controladoFórmula:C18H29NO5Forma y color:NeatPeso molecular:339.43[2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl Acetate
CAS:Fórmula:C24H25ClN6O2(R)-Betaxolol Hydrochloride
CAS:Producto controladoApplications (R)-Betaxolol is the R-isomer of Betaxolol (B328000), a cardioselective β1-adrenergic blocker (1,2,3). It is also an antihypertensive and antiglaucoma agent (4). References (1) Bickel, M., et al.: J. Pharm. Pharmacol., 32, 669 (1980)(2) Cadigan, P.J., et al.: Br. J. Clin. Pharmacol., 9, 569 (1980) (3) Pathe, M., et al.: Therapie, 37, 75 (1982)(4) Panchal, V. S., et al.: J. Pharm. Sci. Pharmacol. 2, 21 (2015)Fórmula:C18H29NO3·ClHForma y color:NeatPeso molecular:343.89rac D 617 (Verapamil Metabolite)
CAS:Producto controladoApplications A metabolite of Verapamil (V125000). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Jones, O., et al.: Environ. Sci. Technol., 41, 5085 (2007),Fórmula:C17H26N2O2Forma y color:NeatPeso molecular:290.403-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid
CAS:Producto controladoFórmula:C13H10N2O7SForma y color:NeatPeso molecular:338.297-[4-(4-Fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyheptanoic Acid Calcium Salt
Fórmula:C22H29FN3O6S·CaForma y color:NeatLANDIOLOL HYDROCHLORIDE
CAS:Producto controladoApplications Landiolol is an ultra-short acting beta blocker that is used to treat patients with cardiac arrhythmias and is also used to treat tachycardia during anasthesia. References Atarashi, H., et al.: Clin. Pharmacol. Ther., 68, 143 (2000); Harasawa, R., et al.: J. Cardiothor. Vasc. An., 20, 793 (2006);Fórmula:C25H39N3O8·ClHForma y color:NeatPeso molecular:546.052-Chloro-N,N-diethylethanamine Hydrochloride (2-Chlorotriethylamine Hydrochloride; (2-Chloroethyl)diethylamine Hydrochloride)
CAS:Producto controladoFórmula:C6H14ClN·ClHLabetalol Impurity 1
CAS:Fórmula:C23H22N2O3Forma y color:White To Off-White SolidPeso molecular:374.44Timolol EP Impurity G
CAS:Fórmula:C6H9N3O3SForma y color:White To Off-White SolidPeso molecular:203.223-[3-Acetyl-4-[(2RS)-3-(diethylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea
CAS:Fórmula:C20H33N3O4(S)-Isotimolol
CAS:Producto controladoApplications An isomer of the antiarrhythmic, antiglaucoma agent Timolol (T443700). References Marini, R.D. et al.: Anal. Chim. Acta, 531, 131 (2005);Fórmula:C13H24N4O3SForma y color:WhitePeso molecular:316.42O-Desethyl O-Propyl Sildenafil
CAS:Producto controladoApplications O-Desethyl O-Propyl Sildenafil is an impurity of Sildenafil (S435001); an orally active selective type 5 cGMP phosphodiesterase inhibitor. References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)Fórmula:C23H32N6O4SForma y color:NeatPeso molecular:488.605-(2-Aminoethyl)-2-methoxyphenol Hydrochloride (4-O-Methyldopamine Hydrochloride)
CAS:Producto controladoFórmula:C9H13NO2·ClHForma y color:NeatPeso molecular:203.67Diethyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS:Fórmula:C19H21Cl2NO4Acebutolol-d5
CAS:Producto controladoApplications Cardioselective β-adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II). References Cuthbert, O.A., et al.: Br. J. Pharmacol., 43, 639 (1971), Singh, B.N., et al.: Drugs, 29, 531 (1985), Foster, R.T., et al.: Anal. Profiles Drug Subs., 19, 1 (1990),Fórmula:C18H23D5N2O4Forma y color:NeatPeso molecular:341.464’-Hydroxyphenprocoumon
CAS:Producto controladoApplications 4’-Hydroxyphenprocoumon is a metabolite of the oral anticoagulant Phenprocoumon (P318820). References De Vries, J. et al.: J. Chrom. Biomed. Appl., 529, 479 (1990);Fórmula:C18H16O4Forma y color:NeatPeso molecular:296.32Dimetofrine
CAS:Producto controladoApplications Dimetofrine is a cardiac stimulant used in the treatment of post-partum hypotension. Dimetofrine showed selective agonist activity on the a1-adrenergic receptor. References Marsoni V. Curr. Med. Res. Opin., 9, 578 (1985); Cuccurullo, F. et al.: Boll. Soc. Ital. Cardiol., 18, 407 (1973); Cuccurullo, F. et al.: Clin. Terap., 79, 347 (1976);Fórmula:C11H17NO4Forma y color:NeatPeso molecular:227.26Ezetimibe Ketone Benzyl Ether
CAS:Producto controladoFórmula:C31H25F2NO3Forma y color:NeatPeso molecular:497.53CK 1827452
CAS:Producto controladoApplications CK 1827452 is a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction. References Meijs, M. et al.: Eur. J. Heart. Fail., 14, 232 (2012); Malik, F. et al.: J. Mol. Cell. Card., 51, 454 (2011)Fórmula:C20H24FN5O3Forma y color:NeatPeso molecular:401.434-Isobutylbenzoic Acid
CAS:Producto controladoFórmula:C11H14O2Forma y color:NeatPeso molecular:178.23N-Des(methylsulfonyl)-N-[[2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-2-hydroxyethyl]sulfonyl]rosuvastatin Calcium
Fórmula:C38H45F2N6O9S2·CaForma y color:NeatDoxazosin EP Impurity D (Doxazosin USP Related Compound B)
CAS:Producto controladoFórmula:C10H10N2O4Forma y color:NeatPeso molecular:222.20Captopril Ethyl Ester
CAS:Producto controladoFórmula:C11H19NO3SForma y color:NeatPeso molecular:245.34Atenolol EP Impurity H
CAS:Fórmula:C14H20N2O2Forma y color:White To Off-White SolidPeso molecular:248.33Ethyl 4-(2,3,4-Trimethoxybenzyl)piperazine-1-carboxylate
CAS:Producto controladoFórmula:C17H26N2O5Forma y color:NeatPeso molecular:338.407-Hydroxy Coumarin-13C6 Beta-D-Glucuronide Sodium Salt
CAS:Producto controladoApplications A labelled metabolite of 7-Ethoxycoumarin and Coumarin. Useful as a pharmacokinetic standard in metabolic studies. References Blankson, E., et al.: Biochem. Pharmacol., 42, 1241 (1991), Steensma, A., et al.: Xenobiotica, 24, 893 (1994), Fisher, R., et al.: Toxicol. Methods, 5, 99 (1995), Ekins, S., et al.: Drug Metab. Dispos., 24, 990 (1996)Fórmula:C913C6H13NaO9Forma y color:NeatPeso molecular:366.2