Beta-bloqueante

Applications Rosuvastatin-d3 Sodium Salt is the labeled analogue of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic. References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005); Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006)

Applications Antihypertensive, anti-ischemic. References Caillet, S., et al.: Food Chem., 124, 1699 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010), Ferreres, F., et al.: J. Pharm. Biomed. Anal., 51, 65 (2010),

Applications Pravastatin-d9 Sodium, is the labeled analogue of Pravastatin Sodium (P702000), a competitive inhibitor of HMG-CoA reductase, and bioactive metabolite of Mevastatin. References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), Yoshino, G., et al.: Lancet, 2, 740 (1986), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)

Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite. References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),

Betaxolol HCl (SL 75212) is a cardioselective beta-blocker for hypertension without reported liver injury.

Applications Atorvastatin Derivative

Ether-alcohols and their halogenated, sulfonated, nitrated or nitrosated derivatives, nesoi

Applications A labelled metabolite of Cerivastatin, a competitive inhibitor of HMG-CoA reductase. References Boberg, M., et al.: Drug Metab. Dispos., 25, 321 (1997),

Applications (2Z)-2,3-Dehydroxy Atorvastatin is an intermediate in synthesizing (2E)-2,3-Dehydroxy Atorvastatin (D230045), which is an impurity in the synthesis of Atorvastatin (A791750). References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);

Applications It is the labeled analogue of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function). References Papageorgiou, P., et al.: Br. J. Dermatol., 142, 973 (2000), Dreno, B., et al.: Dermatology, 203, 135 (2001), Gollnick, H., et al.: Drugs, 63, 1579 (2003), Seaton, E., et al.: Lancet, 362, 1347 (2003),

1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol] is a synthetic drug product that has been custom synthesized for testing purposes. It is one of the metabolites of the drug product 1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-hydroxypropyl)phenoxy]-2-propanol]. The metabolite has not been found in nature and its structure is unknown. Metabolism studies have been performed on this metabolite to determine its metabolic pathway. This metabolite is an impurity standard for HPLC analysis.

Applications Benzthiazide is a diuretic, antihypertensive agent. References Mollica, J., et al.: J. Pharm. Sci., 58, 635 (1969), Chienthavorn, O., et al.: J. Pharm. Biomed. Anal., 36, 477 (2004),