Moduladores GABA
Los moduladores de GABA son compuestos que influyen en la función de los receptores de GABA (ácido gamma-aminobutírico), los principales receptores inhibitorios de neurotransmisores en el sistema nervioso central. Estos moduladores pueden aumentar o inhibir la actividad GABAérgica, afectando la excitabilidad neuronal y la transmisión sináptica. Los moduladores de GABA son cruciales en el tratamiento y estudio de varios trastornos neurológicos y psiquiátricos, incluyendo ansiedad, epilepsia e insomnio. En CymitQuimica, ofrecemos una amplia gama de moduladores de GABA para apoyar su investigación en neurociencia, farmacología y neuroterapéutica.
Productos de "Moduladores GABA"
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7-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:166.19900512695312Flubromazepam
CAS:Producto controladoApplications Flubromazepam is a designer benzodiazepine drug structurally related to Phenazepam (P295300); a drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. Phenazepam (P295300) can also be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety. References Moosmann, B., et al.: J. Mass Spectrom., 48, 1150 (2013); Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989); Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993); Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008)Fórmula:C15H10BrFN2OForma y color:WhitePeso molecular:333.164-Boc-2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:248.32600402832032,2’-(1,4-Piperazinediyl)bis-pyrimidine
CAS:Producto controladoImpurity Buspirone EP Impurity G Applications 2,2’-(1,4-Piperazinediyl)bis-pyrimidine is an impurity of Buspirone (B689850), an non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. References Quaglia, M.G., et al.: J. Pharma. Biomed. Anal., 13, 505 (1995);Fórmula:C12H14N6Forma y color:NeatPeso molecular:242.28Butalbital-d5
CAS:Producto controladoApplications Labelled Butalbital (B690100). Controlled substance (depressant). Sedative, hypnotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Inaba, T., et al.: Clin. Pharmacol. Ther., 18, 558 (1975), Fritch, D., et al.: J. Anal. Toxicol., 33, 569 (2009), Wille, S., et al.: Ther. Drug Monit., 31, 511 (2009),Fórmula:C112H5H11N2O3Forma y color:WhitePeso molecular:229.297-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE HCL
CAS:Pureza:95.0%Peso molecular:263.55999755859375Secbutabarbital
CAS:Producto controladoApplications Controlled substance (depressant). Sedative, hypnotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Heller, D., et al.: J. Agric. Food Chem., 49, 4597 (2001), Ramirez, A., et al.: Anal. Chem., 79, 3155 (2007),Fórmula:C10H16N2O3Forma y color:WhitePeso molecular:212.256-Chloro-2-(chloromethyl)-4-phenyl-quinazoline
CAS:Producto controladoApplications Chlordiazepoxide (C327050) derivative.Fórmula:C15H10Cl2N2OForma y color:NeatPeso molecular:305.1610H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-4-oxido-1-piperazinyl)-
CAS:Fórmula:C17H20N4OSPureza:97%Forma y color:SolidPeso molecular:328.4319Pentanenitrile (Valeronitrile)
CAS:Producto controladoFórmula:C5H9NForma y color:NeatPeso molecular:83.135,10-Dihydro-2-methyl-4H-thieno[2,3-β][1,5]benzodiazepin-4-one (Olanzapine Impurity)
CAS:Fórmula:C12H10N2OSPureza:96%Forma y color:SolidPeso molecular:230.2856Ref: IN-DA00C31Z
Producto descatalogadoMethylphenobarbital-d3
CAS:Producto controladoApplications Controlled substance (depressant). Anticonvulsant; sedative; hypnotic. References Price, W.C., et al.: J. Pharm. Pharmacol., 6, 522 (1954), Brochman-Hanssen, E., et al.: J. Pharm. Sci., 58, 370 (1969), Lackner, H., et al.: Arch. Toxikol., 26, 220 (1970),Fórmula:C13H11D3N2O3Forma y color:NeatPeso molecular:249.28Flubromazepam (7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one) 1.0 mg/ml in Methanol
CAS:Producto controladoFórmula:C15H10BrFN2O5-Methyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
CAS:Producto controladoFórmula:C11H10N2O3Forma y color:NeatPeso molecular:218.21Nitrazepam (100μg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C15H11N3O3Forma y color:ColourlessPeso molecular:281.27Zolpidem Phenyl-4-carboxylic Acid
CAS:Applications A major metabolite of Zolpidem. References Crestani, F., et al.: Br. J. Pharmacol., 131, 1251 (2000), Li, Q., et al.: Bioorg. Med. Chem. Lett., 12, 465 (2002), Goulle, J., et al.: Ther. Drug Monit., 26, 206 (2004), Ohkanda, J., et al.: J. Med. Chem., 47, 432 (2004), Blackaby, W., et al.: Bioorg. Med. Chem. Lett., 16, 1175 (2006),Fórmula:C19H19N3O3Forma y color:Off-White To Light BeigePeso molecular:337.37(2S)-2-(5-Fluoro-2,4-dinitroanilino)propanamide
CAS:Producto controladoFórmula:C9H9FN4O5Forma y color:NeatPeso molecular:272.192-Hydroxypropyl 4-(2-Chlorophenyl)-6-nitro-quinazoline-2-carboxylate
Fórmula:C18H14ClN3O5Forma y color:Neat5-Allyl-6-imino-5-(1-methyl-2-pentynyl)hydrouracil
CAS:Producto controladoFórmula:C13H17N3O2Forma y color:NeatPeso molecular:460.6067-Fluoro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:194.1649932861328N-Desmethyl Clotiazepam
CAS:Producto controladoApplications Clotiazepam (C587410) metabolite, with central nervous depressant and anxiolytic activity. References Ito, K. et al.: Biopharm. Drug. Dispos., 18, 293 (1997); Nakanishi, M. et al.: J. Med. Chem., 16, 214 (1973)Fórmula:C15H13ClN2OSForma y color:NeatPeso molecular:304.79Clotiazepam
CAS:Producto controladoApplications A thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to benzodiazepine site of the GABAA receptor where it acts as a full agonist resulting in enhanced GABA inhibitory effect at the GABAA receptor. Controlled Substance. References Mandrioli, R. et al.: Curr.Drug Metab., 8, 827 (2008); Nakazawa, Y. et al.: Psychopharmacol., 44, 165 (1975); Yakushiji, T. et al.: Br. J. Pharmacol., 98, 735 (1989);Fórmula:C16H15ClN2OSForma y color:Off-WhitePeso molecular:318.82Methylphenobarbital
CAS:Producto controladoApplications Controlled substance (depressant). Anticonvulsant; sedative; hypnotic. References Price, W.C., et al.: J. Pharm. Pharmacol., 6, 522 (1954), Brochman-Hanssen, E., et al.: J. Pharm. Sci., 58, 370 (1969), Lackner, H., et al.: Arch. Toxikol., 26, 220 (1970),Fórmula:C13H14N2O3Forma y color:WhitePeso molecular:246.264-(2-Methylpropyl)piperidine-2,6-dione (3-Isobutylglutarimide)
CAS:Producto controladoFórmula:C9H15NO2Forma y color:NeatPeso molecular:169.224-Boc-7-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:266.3160095214844N-Methyl Zonisamide
CAS:Producto controladoApplications A methylated analog of Zonisamide (Z700000) with anticonvulsant activity. References Uno, H., et al.: J. Med. Chem., 22, 180 (1979)Fórmula:C9H10N2O3SForma y color:NeatPeso molecular:226.25Tizanidine Hydrochloride
CAS:Producto controladoApplications An α2-adrenergic agonist; centrally active myotonolytic. A muscle relaxant (skeletal). References Turski, L., et al.: Brain Res., 379, 367 (1986), Ono, H., et al.: Gen. Pharmacol., 17, 137 (1986), Hoogstraten, M.C., et al.: Acta Neurol. Scand., 77, 224 (1988)Fórmula:C9H8ClN5S·ClHForma y color:Light YellowPeso molecular:290.177-Bromo-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Pureza:95+%Peso molecular:269.0979919433594Butobarbital-d5
CAS:Producto controladoApplications Labelled Butobarbital, a barbiturate derivative that is used as a hypnotic agent with sedative and anticonvulsant properties. Butobarbital is a Controlled Substance. References Sitsen, J.M.A. et al.: Pharmac. Week., 109, 1 (1974); Adams, R.G.: Psychopharmacologia, 40, 185 (1974);Fórmula:C10H11D5N2O3Forma y color:NeatPeso molecular:217.28N-Demethyl Olanzapine
CAS:Producto controladoApplications A metabolite of Olanzapine.Fórmula:C16H18N4SForma y color:BrownPeso molecular:298.416-(8-Chloro-4,5-dihydro-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ylidene)-2,4-cyclohexadien-1-one
CAS:Producto controladoFórmula:C18H14ClN3OForma y color:NeatPeso molecular:323.78Oxcarbazepine EP Impurity F
CAS:Producto controladoFórmula:C16H12ClNO2Forma y color:NeatPeso molecular:286.00Nitrazepam (1.0 mg/mL in Acetonitrile)
CAS:Producto controladoFórmula:C15H11N3O3Forma y color:ColourlessPeso molecular:281.274-Boc-8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:266.3160095214844
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