Moduladores GABA
Los moduladores de GABA son compuestos que influyen en la función de los receptores de GABA (ácido gamma-aminobutírico), los principales receptores inhibitorios de neurotransmisores en el sistema nervioso central. Estos moduladores pueden aumentar o inhibir la actividad GABAérgica, afectando la excitabilidad neuronal y la transmisión sináptica. Los moduladores de GABA son cruciales en el tratamiento y estudio de varios trastornos neurológicos y psiquiátricos, incluyendo ansiedad, epilepsia e insomnio. En CymitQuimica, ofrecemos una amplia gama de moduladores de GABA para apoyar su investigación en neurociencia, farmacología y neuroterapéutica.
Productos de "Moduladores GABA"
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Lormetazepam-13C,d3
CAS:Producto controladoApplications A labelled analog of Lorazepam (L469850). Sedative, hypnotic.Controlled substance (depressant). References Nudelman, A., et al.: J. Pharma. Sci., 63, 1886 (1974), Humpel, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 4, 237 (1979), Girkin, R., et al.: Xenobiotica, 10, 401 (1980),Fórmula:CC15D3H9Cl2N2O2Forma y color:NeatPeso molecular:339.204-Methylimidazole
CAS:Applications 4-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 4-Methylimidazole is a product which results from the interaction of reducing sugars with ammonia. 4-Methylimidazole showed convulsant activity in animals and is listed as a possible carcinogen. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969): Cunha, S.C. et al.: J. Food Comp. Anal., 24, 609 (2011); Chan, P.C. et al.: Arch. Toxicol., 82, 55 (2008);Fórmula:C4H6N2Forma y color:Light YellowPeso molecular:82.109-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Peso molecular:162.23599243164062Lorazepam
CAS:Producto controladoImpurity Lorazepam USP Related Compound A Stability hygroscopic Applications Lorazepam is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant. Lorazepam USP Related Compound A.Controlled substance (depressant). References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),Fórmula:C15H10Cl2N2O2Forma y color:NeatPeso molecular:321.16Pentobarbital Sodium Salt (>90%)
CAS:Producto controladoFórmula:C11H17N2O3·NaPureza:>90%Forma y color:WhitePeso molecular:248.25Temazepam (100μg/ml in Methanol)
CAS:Producto controladoFórmula:C16H13ClN2O2Forma y color:ColourlessPeso molecular:300.744-Hydroxy Midazolam (1.0 mg/mL in methanol)
CAS:Producto controladoFórmula:C18H13ClFN3OForma y color:Single SolutionPeso molecular:341.77Temazepam
CAS:Producto controladoApplications Temazepam is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug. References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),Fórmula:C16H13ClN2O2Forma y color:Light YellowPeso molecular:300.744(3H)-Pyrimidinone, 6-hydroxy-2-(propylthio)-
CAS:Fórmula:C7H10N2O2SPureza:97%Forma y color:SolidPeso molecular:186.23157,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Pureza:97.0%Peso molecular:208.26100158691406Chlordiazepoxide
CAS:Producto controladoApplications Controlled substance (depressant). Anxiolytic. Prototype of the benzodiazepine anxiolytics. References MacDonald, A., et al.: Anal. Profiles Drug Subs., 1, 15 (1972); Greenblatt, D.J., et al.: Clin. Pharmacokinet., 3, 381 (1978);Fórmula:C16H14ClN3OForma y color:Light YellowPeso molecular:299.75Midazolam-D4.maleate, 0.1mg/ml in Methanol (as free base)
CAS:Producto controladoFórmula:C182H4H9ClFN3·C4H4O4Amino(diphenyl)acetic Acid (2,2-Diphenylglycine)
CAS:Producto controladoFórmula:C14H13NO2Forma y color:NeatPeso molecular:227.26Eszopiclone-d8
CAS:Producto controladoApplications Eszopiclone is the active stereoizomer of Zopiclone and belongs to the class of drug known as cyclopyrrones. It is a nonbenzodiazepine hypnotic agent used as a treatment for insomnia.This is a controlled substance (depressant) in the US but not in Canada. References Gottesmann, C., et al.: Eur. J. Neurosci., 10, 409 (1998), Yoshimoto, M., et al.: Eur. Neuropsychopharmacol., 9, 29 (1999),Fórmula:C17H9D8ClN6O3Forma y color:NeatPeso molecular:396.86Oxcarbazepine EP Impurity C (Oxcarbazepine USP Related Compound E)
CAS:Producto controladoFórmula:C14H11NOForma y color:NeatPeso molecular:209.24Zopiclone-d8
CAS:Producto controladoApplications Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic. References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),Fórmula:C17H9D8ClN6O3Forma y color:Off-WhitePeso molecular:396.86Dimethyl Phenobarbital-d6
CAS:Producto controladoFórmula:C14H10D6N2O3Forma y color:NeatPeso molecular:266.337-Acetamido Nitrazepam 1.0 mg/mL in Methanol
CAS:Producto controladoFórmula:C17H15N3O2Forma y color:Single SolutionPeso molecular:293.325-Phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:236.2740020751953Etizolam (1.0 mg/mL in Methanol)
CAS:Producto controladoFórmula:C17H15ClN4SForma y color:ColourlessPeso molecular:342.855H-1-Benzazepin-5-one, 7-chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-
CAS:Fórmula:C18H15ClN2O4Pureza:98%Forma y color:SolidPeso molecular:358.77575-Ethyl-5-(1-ethylpropyl)-2-thiobarbituric Acid
CAS:Producto controladoFórmula:C11H18N2O2SForma y color:WhitePeso molecular:242.341',4-Dihydroxy Midazolam
CAS:Producto controladoApplications A metabolite of Midazolam (M343000). References Soucek, P., et al.: Xenobiotica, 22, 83 (1992), Ghosal, A., et al.: Drug Metab. Dispos., 24, 940 (1996), Kobayashi, K., et al.: Biochem. Pharmacol., 63, 889 (2002),Fórmula:C18H13ClFN3O2Forma y color:NeatPeso molecular:357.77
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