Moduladores GABA
Los moduladores de GABA son compuestos que influyen en la función de los receptores de GABA (ácido gamma-aminobutírico), los principales receptores inhibitorios de neurotransmisores en el sistema nervioso central. Estos moduladores pueden aumentar o inhibir la actividad GABAérgica, afectando la excitabilidad neuronal y la transmisión sináptica. Los moduladores de GABA son cruciales en el tratamiento y estudio de varios trastornos neurológicos y psiquiátricos, incluyendo ansiedad, epilepsia e insomnio. En CymitQuimica, ofrecemos una amplia gama de moduladores de GABA para apoyar su investigación en neurociencia, farmacología y neuroterapéutica.
Productos de "Moduladores GABA"
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8-Demethyl-6-hydroxy Zolazepam
CAS:Producto controladoApplications N-Demethylated-8-hydroxylated metabolite of the anesthetic agent, Zolazepam (Z613500). References Baukema, J. et al.: Res. Comm. Chem. Pathol. Pharmacol., 10, 227 (1975);Fórmula:C14H13FN4O2Forma y color:NeatPeso molecular:288.283,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:176.1750030517578Midazolam-D4.maleate, 1mg/ml in Methanol (as free base)
CAS:Producto controladoFórmula:C182H4H9ClFN3·C4H4O43-Hydroxy-prazepam-D5
CAS:Producto controladoFórmula:C19H12D5ClN2O2Forma y color:NeatPeso molecular:345.84Bromazepam
CAS:Producto controladoApplications Controlled substance (depressant). Anxiolytic. References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),Fórmula:C14H10BrN3OForma y color:WhitePeso molecular:316.15Barbituric Acid
CAS:Impurity Fluorouracil EP Impurity A Applications Barbituric Acid (Fluorouracil EP Impurity A) is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties. References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),Fórmula:C4H4N2O3Forma y color:NeatPeso molecular:128.097-Amino Nitrazepam (1mg/ml in Methanol)
CAS:Producto controladoFórmula:C15H13N3OForma y color:Single SolutionPeso molecular:251.28Deschloro-Zopiclone
CAS:Producto controladoApplications Deschloro-Zopiclone is a metabolite of Zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),Fórmula:C17H18N6O3Forma y color:NeatPeso molecular:354.36Gabapentin 100 µg/mL in Acetonitrile:Methanol
CAS:Producto controladoFórmula:C9H17NO2Forma y color:Single SolutionPeso molecular:171.24Pirenzepine dihydrochloride, 99%
CAS:A M1 muscarinic receptor antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C19H23Cl2N5O2Pureza:99%Forma y color:Crystals or powder or crystalline powder, White to pale yellowPeso molecular:424.331-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C10H10N2O2Pureza:95%Forma y color:SolidPeso molecular:190.1986Pentobarbital-d5
CAS:Producto controladoApplications Pentobarbital-d5 is labelled Pentobarbital (P276000, sodium salt) which is a short-acting barbiturate. Typical applications for pentobarbital are sedative, hypnotic for short term, preanesthetic and control of convulsions in emergencies. References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Woster, P.S., et al.: Clin. Pharm., 9, 762 (1990), Evans, A.T., et al.: J. Am. Vet. Med. Assoc., 203, 664 (1993),Fórmula:C112H5H13N2O3Forma y color:WhitePeso molecular:231.30Methyl N-[(2S)-4-Methyl-2-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]pentyl]carbamate
CAS:Forma y color:Neat(Carbamoylamino)(diphenyl)acetic Acid
CAS:Producto controladoFórmula:C15H14N2O3Forma y color:NeatPeso molecular:270.289-Nitro-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Pureza:95.0%Peso molecular:207.188995361328125-(4-Methylphenyl)-5-phenylimidazolidine-2,4-dione
CAS:Producto controladoFórmula:C16H14N2O2Forma y color:NeatPeso molecular:266.29SKF 81297C
CAS:Producto controladoApplications SKF 81297C is a dopamine D1 agonist (1). References (1) Bergman, J., et. al.: J. Pharmacol. Exp. Ther., 273, 40 (1995)Fórmula:C16H17BrClNO2Forma y color:NeatPeso molecular:370.67Lorazepam (100 μg/mL in Acetonitrile)
CAS:Producto controladoFórmula:C15H10Cl2N2O2Forma y color:Single SolutionPeso molecular:321.16
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