Moduladores GABA
Los moduladores de GABA son compuestos que influyen en la función de los receptores de GABA (ácido gamma-aminobutírico), los principales receptores inhibitorios de neurotransmisores en el sistema nervioso central. Estos moduladores pueden aumentar o inhibir la actividad GABAérgica, afectando la excitabilidad neuronal y la transmisión sináptica. Los moduladores de GABA son cruciales en el tratamiento y estudio de varios trastornos neurológicos y psiquiátricos, incluyendo ansiedad, epilepsia e insomnio. En CymitQuimica, ofrecemos una amplia gama de moduladores de GABA para apoyar su investigación en neurociencia, farmacología y neuroterapéutica.
Productos de "Moduladores GABA"
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Tilivalline
CAS:Applications Tilivalline, is a metabolite from Klebsiella oxytoca. Tilivalline, is shown to be cytotoxin, and the key event causing Antibiotic-Associated Hemorrhagic Colitis. References Mori, Sh., et al.: Tetrahedron, 47, No.27, 5051 (1991); Nagasaka, T., et al.: Tetrahedron Lett., 14, 1871 (1989);Fórmula:C20H19N3O2Forma y color:Light BrownPeso molecular:333.38Pyrrolidin-2-one (2-Pyrrolidone)
CAS:Producto controladoFórmula:C4H7NOForma y color:NeatPeso molecular:85.102,3,4,5-Tetrahydro-1H-1,4-benzodiazepine, 95%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C9H12N2Pureza:95%Forma y color:Yellow with orange to pale brown, Crystals or powder or crystalline powder or lumpy solidPeso molecular:148.217-Amino Clonazepam
CAS:Producto controladoApplications The major metabolite of Clonazepam (C587080). References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),Fórmula:C15H12ClN3OForma y color:YellowPeso molecular:285.73Cloxazolam
CAS:Producto controladoApplications Cloxazolam is a benzodiazepine derivative with anxiolytic, hypnotic and antihypertensive properties used as an anti-anxiety drug. It is metabolized into the active metabolite Delorezepam (D230675). Controlled Substance. References Oliveira-Silva, D. et al.: Biomed. Chrom., 23, 1266 (2009); Kamioka, T. et al.: Psychopharmacol., 52, 17 (1977); Fischer-Cornelssen, K.A. et al.: Arzneim.-Forsch., 31, 1757 (1981);Fórmula:C17H14Cl2N2O2Forma y color:NeatPeso molecular:349.21Nimetazepam-d3
CAS:Producto controladoApplications Labelled Nimetazepam (N477800). Sedative, hypnotic. Controlled substance. References Inaba, et al.: Chem. Pharm. Bull., 19, 722 (1971), Sakai, S., et al.: Arzneim.-Forsch., 22, 534 (1972),Fórmula:C16H10D3N3O3Forma y color:NeatPeso molecular:298.318-Chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
CAS:Producto controladoFórmula:C17H12ClFN4Forma y color:NeatPeso molecular:326.765-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (Flubromazepam Isomer)
CAS:Fórmula:C15H10BrFN2OPirenzepine, Dihydrochloride
CAS:Producto controladoApplications An antiulcerative. Tricyclic gastric-acid inhibitor. References Eberlein, W., et al.: Arzneimittel-Forsch., 27, 356 (1977), Hellerr, G., et al.: Verh. Deut. Ges. Inn. Med., 84, 991 (1978), Carmine, A.A., et al.: Drugs, 30,85 (1985), El-Obeid, H.A., et al.: Anal. Profiles Drug Subs., 16, 445 (1987), Homon, C.A., et al.: Ther. Drug Monit., 9, 236 (1987),Fórmula:C19H21N5O2·2ClHForma y color:NeatPeso molecular:424.324-Amino-2-methyl-10H-thieno[2,3-b][1,5]-benzodiazapine, Hydrochloride
CAS:Producto controladoImpurity Olanzapine Impurity 6 HCl Applications Intermediate in the preparation of Olanzapine (O253750). Olanzapine Impurity 6 HCl. References Calligaro, D., et al.: Bioorg. Med. Chem. Lett., 7, 25 (1997),Fórmula:C12H11N3S·ClHForma y color:NeatPeso molecular:265.76Sultiame 100 µg/mL in Acetonitrile
CAS:Fórmula:C10H14N2O4S2Forma y color:Single SolutionPeso molecular:290.362-Bromo-2'-(2-chlorobenzoyl)-4'-nitroacetanilide
CAS:Producto controladoFórmula:C15H10BrClN2O4Forma y color:NeatPeso molecular:397.61Levetiracetam EP Impurity C
CAS:Producto controladoFórmula:C5H5NOForma y color:NeatPeso molecular:95.10N-Descarboxymethyl-N-carboxyethyl Lacosamide (Impurity)
CAS:Producto controladoApplications N-Descarboxymethyl-N-carboxyethyl Lacosamide is an impurity of Lacosamide (L098500), an anticonvulsant drug that enhances sodium channel slow inactivation, and is used to treat patients with epilepsy. References Doty, P., et al.: Neurotherapeutics, 4, 145 (2007); Perucca, E., et al.: Nat. Rev. Drug Discov., 7, 973 (2008); Sake, J., et al.: CNS Drugs, 24, 1055 (2010)Fórmula:C14H20N2O3Forma y color:NeatPeso molecular:264.327-Amino Nimetazepam
CAS:Producto controladoApplications A metabolite of Nimetazepam. Controlled substance. References Nishikawa, M., et al.: Forensic Sci. Int., 66, 149 (1994), Katagi, M., et al.: J. Anal. Toxicol., 24, 354 (2000),Fórmula:C16H15N3OForma y color:NeatPeso molecular:265.31Lixivaptan
CAS:Producto controladoApplications Drug used in the treatment and prevention of cardiovascular diseases. References Lo, R., et al.: Curr. Clin. Pharmacol., 3, 156 (2008), Ghali, J., et al.: Cardiol., 111, 147 (2008),Fórmula:C27H21ClFN3O2Forma y color:NeatPeso molecular:473.93Phenobarbital
CAS:Producto controladoApplications This is a controlled substance (depressant). Anticonvulsant; sedative; hypnotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Chao, M.K.C., et al.: Anal. Profiles Drug Subs., 7, 359 (1978),Fórmula:C12H12N2O3Forma y color:White To Off-WhitePeso molecular:232.247-Amino Clonazepam-d4
CAS:Producto controladoApplications A labelled major metabolite of Clonazepam (C587080). References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),Fórmula:C152H4H8ClN3OForma y color:Yellow To Light Orange ColourPeso molecular:289.754-Hydroxy Midazolam (100 μg/mL in methanol)
CAS:Producto controladoFórmula:C18H13ClFN3OForma y color:Single SolutionPeso molecular:341.77Phenazepam
CAS:Producto controladoApplications A benzodiazepine drug, which is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety. References Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989), Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993), Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008),Fórmula:C15H10BrClN2OForma y color:Light YellowPeso molecular:349.61
![8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC990318.webp&w=3840&q=75)
![4-Amino-2-methyl-10H-thieno[2,3-b][1,5]-benzodiazapine, Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA618255.webp&w=3840&q=75)
