Hormonas en Proteínas Recombinantes

Stability Hygroscopic Applications A labelled glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal). References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972), Bernstein, I.L., et al.: Chest, 81, 20 (1982),

PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.

Stability Light Sensitive Applications An antineoplastic (hormonal). References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)

Applications A synthetic progesterone, used to induce oestrus synchronisation in goats and sheep. References Mei, C., et al.: Reproduct. Dom. An., 44, 735 (2009), Letelier, C., et al.: Theriogenol., 71 676 (2009), Letelier, C., et al.: Fertil. Steril., 93, 1308 (2010),

Applications Ketoconazole-d3 is the labeled analogue of Ketoconazole (K186000), which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986); Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989); Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988); Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)

Applications 2-Isobutyryl-N-phenyl-3-phenylacrylamide is the labeled analogue of 2-Isobutyryl-N-phenyl-3-phenylacrylamide (I781040), an intermediate for the synthesis of Atorvastatin-d5 Sodium Salt (A791753), the labeled analogue of Atorvastatin (A791750) (1,2,3). Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References (1) Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993) (2) Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996) (3) Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)

Stability Hygroscopic Applications A metabolite of Triamcinolone acetonide. References Edsbacker, S., et al.: Drug Metab. Dispos., 11, 590 (1983), Szefler, S., et al.: Eur. J. Clin. Pharmacol., 30, 323 (1986), Hansel, T., et al.: J. Immunol. Methods, 145, 105 (1991), Argenti, D., et al.: J. Clin. Pharmacol., 39, 695 (1999),

Applications Glycine 6-Ethylchenodeoxycholate-d5 is the labelled version of Glycine 6-Ethylchenodeoxycholate (G625250) which can be used as reactant/reagent in synthetic preparation of bile acid analogs as FXR/TGR5 agonists. References Or, Y., et al.: PCT Int. Appl., WO 2016073767 A1 20160512 (2016)

Applications Labelled Choleretic. References Mills, K.A., et al.: Pedatric Research, 43, 3 (1998)

Stability Hygroscopic Applications Cholenoic acid present in significant proportions during early gastation. References Setchell, K., et al.: J. Biol. Chem. 263, 16637 (1988), Nakagawa, M., et al.: J. Lipid Res., 31, 1089 (1990),