Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Productos de "Sistema complementario"
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C1QA Protein, Human, Recombinant (GST)
C1QA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 50.58 kDa and the accession number is P02745.Forma y color:LiquidPeso molecular:50.58 kDa (predicted)Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Fórmula:C24H32N2O6Pureza:99.2%Forma y color:SolidPeso molecular:444.52Ref: TM-T10863
1mg92,00€5mg182,00€10mg264,00€25mg406,00€50mg540,00€100mg735,00€200mg938,00€1mL*10mM (DMSO)200,00€Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Fórmula:C128H190N24O33Forma y color:SolidPeso molecular:2593.02JR14a
CAS:JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.Fórmula:C25H26Cl2N4O3SPureza:99.76%Forma y color:SolidPeso molecular:533.47Ref: TM-T9316
1mg92,00€5mg188,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)215,00€Complement C3 Protein, Human, Recombinant (His)
Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 93.4%; SEC-HPLC: 94.7% - SDS-PAGE: 95.5%; SEC-HPLC: 92.6%Forma y color:Lyophilized PowderPeso molecular:186.43 kDa (predicted)Properdin Protein, Mouse, Recombinant (His)
A positive regulator of the alternate pathway of complement.Forma y color:Lyophilized PowderPeso molecular:51.9 kDa (predicted)Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Forma y color:Lyophilized PowderPeso molecular:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Forma y color:Crystals From Ether (Ntp 1992)Peso molecular:392.46MBL1 Protein, Rat, Recombinant (hFc)
MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:50.5 kDa (predicted); 56 kDa (reducing conditions)Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:39.5 kDa (predicted)C1QTNF1 Protein, Human, Recombinant (His)
C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain.Forma y color:Lyophilized PowderPeso molecular:37 KDa (reducing condition)Complement C8 γ Protein, Human, Recombinant (His)
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.Forma y color:Lyophilized PowderPeso molecular:22 KDa (reducing condition)Complement C5a Protein, Pig, Recombinant (His)
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process.Forma y color:Lyophilized PowderPeso molecular:10.6 kDa (predicted)Complement C3 Protein, Mouse, Recombinant (His & SUMO)
Complement C3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:55.3 kDa (predicted)MBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Pureza:> 99.9% - > 99.9%Forma y color:Lyophilized PowderPeso molecular:31 KDa (reducing condition)Complement C4-B Protein, Human, Recombinant (His & SUMO)
Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.Forma y color:Lyophilized PowderPeso molecular:49.1 kDa (predicted)ADH-503
CAS:ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.Fórmula:C27H28N2O5S2Pureza:100% - 98.28%Forma y color:SolidPeso molecular:524.7Complement factor I Protein, Mouse, Recombinant (His)
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible forForma y color:Lyophilized PowderPeso molecular:66.39 kDa (predicted). Due to autocatalytic cleavage and glycosylation, the protein migrates to 80-100 kDa on Tris-Bis PAGE result.CP-447697
CAS:CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.Fórmula:C29H26ClF2N3O2SPureza:99.62%Forma y color:SoildPeso molecular:554.05Avacopan
CAS:Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.Fórmula:C33H35F4N3O2Pureza:99.75% - 99.9%Forma y color:SolidPeso molecular:581.64Properdin Protein, Mouse, Recombinant (His & Myc)
A positive regulator of the alternate pathway of complement.Forma y color:Lyophilized PowderPeso molecular:53 kDa (predicted)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His) is expressed in HEK293 Cells. The accession number is P01027-1.Forma y color:Lyophilized PowderPeso molecular:185.65 kDa (predicted); 156.7 kDa、 107.3 kDa and 56.5 kDa (reducing contition)Complement C7 Protein, Human, Recombinant (hFc)
Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:118 kDa (predicted); 118 kDa (reducing conditions)MASP2 Protein, Rat, Recombinant (E. coli, His)
MASP2 Protein, Rat, Recombinant (E.Forma y color:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.Complement C5a Protein, Mouse, Recombinant
Complement C5a Protein, Mouse, Recombinant is expressed in E.Pureza:97.4%Forma y color:Lyophilized PowderPeso molecular:9 kDa (predicted)Complement C5 Protein, Human, Recombinant (Flag)
Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag.Forma y color:Lyophilized PowderPeso molecular:187.36 kDa (predicted); 176.6 kDa, 100.87 kDa and 72.07 kDa (reducing conditions)Factor B-IN-5
CAS:Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Fórmula:C27H32N2O4Pureza:98.53%Forma y color:SoildPeso molecular:448.55Complement factor I Protein, Human, Recombinant (His)
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible forForma y color:Lyophilized PowderPeso molecular:64.58 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.C1RA Protein, Mouse, Recombinant (His & Myc)
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.Forma y color:Lyophilized PowderPeso molecular:85.7 kDa (predicted)Complement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Forma y color:Lyophilized PowderPeso molecular:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.C5AR1 Protein, Mouse, Recombinant (His & KSI)
C5AR1 Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli with N-6xHis-KSI. The accession number is P30993.Forma y color:Lyophilized PowderPeso molecular:20.4 kDa (Predicted)Complement C2 Protein, Mouse, Recombinant (His)
Complement C2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:84.2 kDa (predicted); 91.2 kDa (reducing conditions)Complement C8g Protein, Human, Recombinant (His)
C8 is a constituent of the membrane attack complex.Pureza:95%Forma y color:Lyophilized PowderPeso molecular:26.4 kDa (predicted)Complement C3a Protein, Human, Recombinant
Complement C3a Protein, Human, Recombinant is expressed in E.Pureza:100% - 100%Forma y color:Lyophilized PowderPeso molecular:13 KDa (reducing condition)MASP2 Protein, Mouse, Recombinant (His)
MASP2 Protein, Mouse, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:46.6 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.Complement C6 Protein, Human, Recombinant (His)
Complement C6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:104 kDa (predicted); 110 kDa (reducing conditions)Complement factor D Protein, Rat, Recombinant (His & Myc)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateForma y color:Lyophilized PowderPeso molecular:29.8 kDa (predicted)NH2-C6-ARC186
NH2-C6-ARC186 is a derivative of the aptamer ARC186, featuring an NH2-C6 moiety that enables coupling to various peptides or molecules.Pureza:98%Forma y color:SolidPeso molecular:128813-Phenoxybenzaldehyde
CAS:3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.Fórmula:C13H10O2Pureza:98.61%Forma y color:SolidPeso molecular:198.22Complement C2 Protein, Human, Recombinant (hFc)
Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:110 kDa (predicted); 110-130 kDa (reducing condition, due to glycosylation)MASP2 Protein, Cynomolgus, Recombinant (His)
MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:46.8 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Tris-Bis PAGE result.Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Forma y color:Lyophilized PowderPeso molecular:95-120 KDa (reducing condition)C1QA Protein, Mouse, Recombinant (E. coli, His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Pureza:98%Forma y color:Lyophilized PowderPeso molecular:29.1 kDa (predicted)Complement C5 Protein, Human, Recombinant (Complement C5a)
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E.Pureza:SDS-PAGE: 94.9%; SEC-HPLC: 93.5%Forma y color:Lyophilized PowderPeso molecular:8.3 kDa (predicted); 8.3 kDa (reducing conditions)MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E.Forma y color:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.Complement factor I Protein, Rat, Recombinant (His & Myc)
Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.Forma y color:Lyophilized PowderPeso molecular:69.2 kDa (predicted)Complement factor D-IN-2
CAS:Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.Fórmula:C27H24BrN7O3Pureza:99.51%Forma y color:SolidPeso molecular:574.43Ref: TM-T38332
1mg111,00€5mg255,00€10mg380,00€25mg672,00€50mg950,00€100mg1.235,00€200mg1.673,00€1mL*10mM (DMSO)316,00€Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Forma y color:Lyophilized PowderPeso molecular:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.MBL2 Protein, Mouse, Recombinant
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix.Forma y color:Lyophilized PowderPeso molecular:28 KDa (reducing condition)Compstatin
CAS:Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.Fórmula:C66H99N23O17S2Pureza:100%Forma y color:SolidPeso molecular:1550.77
