Nucleósidos y Nucleótidos
Los nucleósidos son compuestos formados por una base nitrogenada unida a una azúcar (ribosa o desoxirribosa). Cuando un grupo fosfato se añade al nucleósido, se forma un nucleótido. Estos compuestos son fundamentales en la biología celular, ya que los nucleótidos son los bloques básicos del ADN y ARN, responsables de almacenar y transmitir información genética. Los nucleósidos tienen aplicaciones en el tratamiento de enfermedades virales, como inhibidores de la replicación viral. Los nucleótidos, además de su rol estructural en los ácidos nucleicos, intervienen en procesos energéticos, como en la síntesis de ATP.
En CymitQuimica contamos con una amplia gama de nucleósidos y nucleótidos esenciales para investigación en biología molecular, virología y farmacología.
Productos de "Nucleósidos y Nucleótidos"
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Azacitidine Impurity 16
Fórmula:C10H14N4O6Forma y color:White To Off-White SolidPeso molecular:286.24NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFórmula:C21H26N7Na4O17P3Pureza:100% - 99.65%Forma y color:SolidPeso molecular:833.35Azacitidine Impurity 13
CAS:Fórmula:C8H13N5O5Forma y color:White To Off-White SolidPeso molecular:259.22ent-Entecavir
CAS:Producto controladoApplications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900). References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);Fórmula:C12H15N5O3Forma y color:NeatPeso molecular:277.28Casein kinase 1δ-IN-9
CAS:Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.Fórmula:C15H12ClN3Pureza:99.74%Forma y color:SolidPeso molecular:269.73Ref: TM-T64376
1mg96,00€5mg197,00€10mg295,00€25mg474,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)180,00€Entecavir (1S,3S,4S) diastereomer
CAS:Entecavir is a drug product that is custom synthesized to order. It has a purity of >98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Fórmula:C12H15N5O3Pureza:Min. 95%Peso molecular:277.28 g/molEIDD-2801
CAS:EIDD-2801 (Molnupiravir) is a prodrug for N 4-hydroxycytidine, effective against influenza and various coronaviruses.Fórmula:C13H19N3O7Pureza:100% - 99.70%Forma y color:SolidPeso molecular:329.31Ref: TM-T8309
1g657,00€5mg40,00€10mg60,00€25mg79,00€50mg119,00€100mg187,00€200mg350,00€500mg449,00€1mL*10mM (DMSO)66,00€Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFórmula:C8H9FN3Na4O12P3SPureza:98%Forma y color:SolidPeso molecular:575.11rac-Melphalan EP Impurity B DiHCl
CAS:Fórmula:C13H18N2O3·2HClForma y color:Pale Purple SolidPeso molecular:250.30 2*36.462'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.Fórmula:C9H12F2N2O6Pureza:Min. 95%Peso molecular:282.2 g/molGS-443902
CAS:Remdesivir triphosphate (GS-443902) inhibits RSV/HCV RdRp with IC50s: 1.1/5 µM.Fórmula:C12H16N5O13P3Pureza:98%Forma y color:SolidPeso molecular:531.2Peramivir Impurity 29
CAS:Fórmula:C15H28N4O4Forma y color:White To Off-White SolidPeso molecular:328.41Ganciclovir Impurity 1 HCl (Mixture of Diastereomers)
CAS:Fórmula:C15H24N6O5·HClForma y color:White To Off-White SolidPeso molecular:368.39 36.46Capecitabine Impurity 9
CAS:Fórmula:C20H30FN3O9Forma y color:White To Off-White SolidPeso molecular:475.47Ademethionine-d3 1,4-Butanedisulfonate
CAS:Fórmula:C19H30D3N6O11S3C4H8O6S2Peso molecular:620.70 122.16rac-Melphalan-d8
CAS:Fórmula:C13H10D8Cl2N2O2Forma y color:White To Off-White SolidPeso molecular:313.25Cytarabine EP Impurity I
CAS:Fórmula:C10H15N3O5Forma y color:White To Off-White SolidPeso molecular:257.25Emtricitabine Sulfoxide
CAS:Producto controladoFórmula:C8H10FN3O4SForma y color:NeatPeso molecular:263.25Peramivir Impurity 17
CAS:Fórmula:C12H19NO4Forma y color:White To Off-White SolidPeso molecular:241.295-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Fórmula:C8H12N4O5Pureza:99.31% - 99.79%Forma y color:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:244.22,3'-Anhydrothymidine
CAS:2,3'-Anhydrothymidine is a piperidine-containing nucleoside analog that inhibits the replication of HIV and other viruses. It is structurally related to acyclovir, but has an increased resistance to viral inactivation by acyclovir-resistant strains. 2,3'-Anhydrothymidine binds to the ribose sugar of the viral nucleic acid and prevents the formation of a covalent bond between the 5' hydroxyl group of ribose and the 3' phosphate group. It also inhibits protein synthesis by interfering with the incorporation of amino acids into proteins. 2,3'-Anhydrothymidine has been shown to be effective against human immunodeficiency virus type 1 (HIV-1) in animal models and clinical studies.Fórmula:C10H12N2O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:224.21 g/molPyrithioxin
CAS:Pyrithioxin (Encefabol), a nootropic, enhances cerebral metabolism and, with HV, aids hemiplegic stroke recovery.Fórmula:C16H20N2O4S2Pureza:98.40%Forma y color:Almost White Crystalline PowderPeso molecular:368.47Aciclovir (Acyclovir) EP Impurity M
CAS:Fórmula:C12H15N5O5Forma y color:Off-White SolidPeso molecular:309.28Valaciclovir EP Impurity G (Valacyclovir USP Related Compound G, DMAP)
CAS:Fórmula:C7H10N2Forma y color:White To Off-White SolidPeso molecular:122.172-[[2-(Acetylamino)-6-oxo-1,6-dihydro-9H-purin-9-yl]methoxy]-3-hydroxypropyl Acetate
CAS:Forma y color:NeatLY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFórmula:C19H22N2O2SPureza:99.34%Forma y color:SolidPeso molecular:342.46Ref: TM-T7706
2mg35,00€5mg52,00€10mg90,00€25mg164,00€50mg239,00€100mg339,00€200mg472,00€1mL*10mM (DMSO)58,00€Lamivudine EP Impurity H
CAS:Fórmula:C8H11N3O4SForma y color:White To Off-White SolidPeso molecular:245.25(S)-4-Hydroxypyrrolidin-2-one
CAS:Producto controladoFórmula:C4H7NO2Forma y color:NeatPeso molecular:101.10Clofarabine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C10H11ClFN5O3Forma y color:White Off-White PowderPeso molecular:303.05345Fludarabine Phosphate EP Impurity F
CAS:Fórmula:C12H18FN5O8PForma y color:White To Off-White SolidPeso molecular:391.28Gemcitabine Diphosphate-13C-15N2 Tri(triethylamine) Salt
Fórmula:C15N2C8H13F2NO10P2·3C6H15NPeso molecular:426.14 3 101.19Decitabine Impurity 4 (Methyl-2-deoxy-alfa-D-Ribopyranoside)
CAS:Fórmula:C6H12O4Forma y color:White To Off-White SolidPeso molecular:148.16Capecitabine Impurity 14 (Mixture of Diastereomers)
Fórmula:C22H28FN3O11Forma y color:Off-White SolidPeso molecular:529.472-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]propane-1,3-diyl Dipropanoate (Ganciclovir Dipropionate)
CAS:Producto controladoFórmula:C15H21N5O6Forma y color:NeatPeso molecular:367.36Dapagliflozin alfa-Isomer
CAS:Fórmula:C21H25ClO6Forma y color:White To Off-White SolidPeso molecular:408.88Peramivir Enantiomer
CAS:Fórmula:C15H28N4O4Forma y color:White To Off-White SolidPeso molecular:328.41Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside
CAS:Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is a synthetic impurity standard for the drug product. It has been used in studies on metabolism and as an analytical reference material. Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is also available as a custom synthesis at high purity.Fórmula:C22H24O6Pureza:Min. 95%Forma y color:White powder.Peso molecular:384.42 g/molGanciclovir sodium
CAS:Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Fórmula:C9H13N5NaO4Pureza:99.47%Forma y color:SolidPeso molecular:278.222-Amino-2'-deoxyadenosine (2,6-diamino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-Purine)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C10H14N6O3Forma y color:White PowderPeso molecular:266.11274Fluorouracil EP Impurity D
CAS:Fórmula:C5H6N2O3Forma y color:White To Off-White SolidPeso molecular:142.11Molnupiravir
CAS:Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.Fórmula:C13H19N3O7Pureza:100% - 99.98%Forma y color:SolidPeso molecular:329.31Ref: TM-T60951
1g1.026,00€5mg40,00€10mg60,00€25mg79,00€50mg119,00€100mg187,00€200mg354,00€500mg748,00€1mL*10mM (DMSO)66,00€Entecavir monohydrate
CAS:Entecavir monohydrate (BMS-200475) is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.Fórmula:C12H15N5O3·H2OPureza:100% - 99.8%Forma y color:White Crystalline PowderPeso molecular:295.3S-(5'-Adenosyl)-L-homocysteine
CAS:Fórmula:C14H20N6O5SForma y color:White To BrownPeso molecular:384.41Dapagliflozin Impurity 2
CAS:Fórmula:C15H14BrClOForma y color:White To Off-White SolidPeso molecular:325.63Remdesivir impurity 12
CAS:Remdesivir impurity 12 is a drug product that is used in research and development. It is a synthetic impurity standard for HPLC analytical methods. Remdesivir impurity 12 is an impurity of the drug, remdesivir, which has antiviral activity against HIV-1. Metabolism studies have been conducted to investigate how this impurity affects the pharmacokinetics of remdesivir. The use of synthetic material ensures high purity and quality for this product.Fórmula:C21H31N6O8PPureza:Min. 95%Peso molecular:526.48 g/molAdenosine
CAS:Applications Adenosine is a nucleotide. References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);Fórmula:C10H13N5O4Forma y color:NeatPeso molecular:267.24N2-Nitroso Folinic Acid (N2-Nitroso Folic Acid USP Related Compound A (Free Form), N2-Nitroso Leucovorin)
Fórmula:C20H22N8O8Peso molecular:502.44Fludarabine Phosphate EP Impurity D
CAS:Fórmula:C5H4FN5Forma y color:Off-White SolidPeso molecular:153.12Ribavirin EP Impurity A (Ribavirin USP Related Compound A)
CAS:Fórmula:C8H11N3O6Forma y color:White To Off-White SolidPeso molecular:245.19Hydroxocobalamin Acetate (Vitamin B12 Analog)
CAS:Fórmula:C64H92CoN13O16PForma y color:Dark Red SolidPeso molecular:1389.42Cytidine 2':3'-cyclic monophosphate monosodium salt
CAS:Fórmula:C9H11N3O7P·NaPeso molecular:304.18 22.99Azathioprine EP Impurity F (Didanosine EP Impurity A, Didanosine USP Related Compound A, Hypoxanthine)
CAS:Fórmula:C5H4N4OPeso molecular:136.11Folic Acid EP Impurity G Ditrifluoroacetate
CAS:Fórmula:C19H19N7O6·2C2HF3O2Peso molecular:441.40 2*114.02Melphalan EP Impurity B DiHCl
CAS:Fórmula:C13H18N2O3·2HClForma y color:Off-White SolidPeso molecular:250.13 2*36.46Gemcitabine EP Impurity B-13C-15N2 HCl (α-Gemcitabine-13C-15N2 HCl)
CAS:Fórmula:C813CH11F2N15N2O4·HClForma y color:White To Off-White SolidPeso molecular:266.18 36.46GKT136901
CAS:GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of PeroxynitriteFórmula:C19H15ClN4O2Pureza:99.16%Forma y color:SolidPeso molecular:366.82'-Deoxyadenosine ((2R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C10H13N5O3Forma y color:White PowderPeso molecular:251.101841-(2,3-Di-O-acetyl-5-deoxy-β-D-ribofuranosyl)-4-amino-5-fluoropyrimidin-2(1H)-one
CAS:Producto controladoFórmula:C13H16FN3O6Forma y color:NeatPeso molecular:329.28Zanamivir
CAS:Zanamivir (GG167) is a guanido-neuraminic acid that is used to inhibit NEURAMINIDASE.Fórmula:C12H20N4O7Pureza:98.84% - 99.98%Forma y color:Colorless Crystalline SolidPeso molecular:332.31Zidovudine diphosphate
CAS:Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.Fórmula:C10H15N5O10P2Forma y color:SolidPeso molecular:427.2Peramivir Impurity 18
CAS:Fórmula:C12H19NO4Forma y color:White To Off-White SolidPeso molecular:241.29Ganciclovir EP Impurity H
CAS:Fórmula:C9H13N5O4Forma y color:White To Off-White SolidPeso molecular:255.23L-Tetrahydrofolic Acid (>70% when packaged)
CAS:Producto controladoStability We have observed that this material decomposes steadily over time. Use immediate Applications L-Tetrahydrofolic Acid is a folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids. We have observed that this material decomposes steadily over time. Use immediately upon receipt. References Prinz-Langenohl, R., et al.: Brit. J. Pharmacol., 158, 2014 (2009), Martin, H., et al.: Anal. Biochem., 402, 137 (2010), Dasarathy, J., et al.: Am. J. Clin. Nut., 91, 357 (2010), Karas-Kuzelicki, N., et al.: Clin. Biochem., 43, 37 (2010),Fórmula:C19H23N7O6Forma y color:NeatPeso molecular:445.43Sofosbuvir Impurity 68
CAS:Fórmula:C31H26FN3O7Forma y color:White To Off-White SolidPeso molecular:571.56Famciclovir Impurity 7
CAS:Fórmula:C10H15N5O3Forma y color:White To Off-White SolidPeso molecular:253.26Brivudine Impurity 6 (Mixture of Isomers)
CAS:Fórmula:C4H6Br2Forma y color:Pale Yellow Clear LiquidPeso molecular:213.90Folic Acid-13C5
CAS:Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),Fórmula:C5C14H19N7O6Forma y color:Dark Yellow To Dark BrownPeso molecular:446.36Valaciclovir EP Impurity E (Valacyclovir USP Related Compound E)
CAS:Fórmula:C21H26N6O6Peso molecular:458.48Sofosbuvir Nucleoside Derivative (GS-331007)
CAS:Fórmula:C10H13FN2O5Forma y color:Off-White To Yellow SolidPeso molecular:260.22Dapagliflozin USP Related Compound A
CAS:Fórmula:C21H25BrO6Forma y color:White To Off-White SolidPeso molecular:453.331'-Epi 2',2'-Difluoro-2'-deoxyuridine
CAS:Applications The epimer of the degradation product of Gemcitabine (G305000), a new antitumor agent. References Anliker, S.L., et al.: J. Pharmaceut. Sci., 83, 716 (1994),Fórmula:C9H10F2N2O5Forma y color:Light Yellow SolidPeso molecular:264.186-Methylpterin
CAS:Producto controladoApplications 6-Methylpterin is a derivative of Folic Acid (F680300) which is a precursor of coenzymes involved in metabolism of various nucleotides and nucleic acids. References Dantola, M.L. et al.: Photochem Photobiol Sci., 9, 1604 (2010);Fórmula:C7H7N5OForma y color:NeatPeso molecular:177.16ent-Lamivudine
CAS:Enantiomer of LamivudineFórmula:C8H11N3O3SPureza:Min. 95%Peso molecular:229.26 g/mol
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