
Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Productos de "Sales y derivados de API"
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Brimonidine Impurity 16 Disodium Salt
Fórmula:C15H12BrN5O4·2NaForma y color:Yellow SolidPeso molecular:406.20 2*22.99Bisoprolol Related Compound D (1-(4-{[(2-Isopropoxyethoxy)methoxy]methyl}phenoxy)-3-(isopropylamino)propan-2-ol fumarate (2:1) salt)
Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters, salts therof, nesoiFórmula:C19H33NO5)2·C4H4O4Forma y color:White SolidPeso molecular:827.02Chitosan (200-600mPa·s, 0.5% in 0.5% Acetic Acid at 20°C)
CAS:Forma y color:White to Light yellow to Light orange powder to crystalTravoprost
CAS:Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analoguesFórmula:C26H35F3O6Forma y color:Colorless Clear Pale Yellow LiquidPeso molecular:500.238576-Deschloro-6-methoxy Cyproterone Acetate
Producto controlado(1β,2β,6β-7α)-17-(Acetyloxy)-6-chloro-1,2-dihydro-7-hydroxy -3'H-cyclopropa[1,2]pregna-1,4-diene-3,20-dione; 6β-Chloro -1β,2β-dihydro-7α,17-dihydroxy-3'Hcyclopropa[1,2]pregna-1,4-diene-3,20-dione 17-Acetate; Cyproterone Acetate EP Impurity GFórmula:C25H32O5Forma y color:NeatPeso molecular:412.52Methyl Cellulose (7000-10000mPa·s, 2% in Water at 20°C)
CAS:Forma y color:White to Almost white powder to crystal(1R,2R)-1-(4-Aminophenyl)-2-(dichloroacetylamino)-1,3-propanediol
CAS:Fórmula:C11H15Cl3N2O3Peso molecular:329.60Terlipressin Impurity 12 (Ditrifluoroacetate)
Fórmula:C55H79N17O16S2(C2HF3O2)Peso molecular:1298.46 : 2(114.02)Prednicarbate Related Compound B (Prednisolone-17-ethylcarbonate)
CAS:Adrenal cortical hormones and their derivatives nesoiFórmula:C24H3207Forma y color:White Crystalline PowderPeso molecular:3520.094887-Amino-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid
CAS:Applications 7-Amino-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid is a cephalosporin derivative with antibacterial activity. 7-Amino-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid is an intermediate in the preparation of Cefmetazole (C242850) and other semi-synthetic antibiotics. References Boyd, D.B. et al.: J. Antibiot., 32, 855 (1979): Iwata, M. et al.: Jap. J. Exp. Med., 48, 401 (1978); Liu, M. et al.: Huax. Shiji, 31, 146 (2009);Fórmula:C10H12N6O3S2Forma y color:Off White SolidPeso molecular:328.37(S)-(+)-Mandelic Acid
CAS:Producto controladoImpurity Atomoxetine EP Impurity E Applications (S)-(+)-Mandelic Acid (Atomoxetine EP Impurity E) is an antiseptic (urinary). References Pessela, B., et al.: Enzyme Microb. Technol., 40, 310 (2007), Carrasco-Lopez, C., et al.: J. Biol. Chem., 284, 4365 (2009),Fórmula:C8H8O3Forma y color:NeatPeso molecular:152.15N-Desmethyl 3-Hydroxy Mepivacaine
CAS:Producto controladoApplications Mepivacaine (M225060) derivative. A metabolite of Ropivacaine (R675000) and Lidocaine (L397800). References Falany, C. et al.; Drug. Metab. Dispos. 27, 1057 (1999)Fórmula:C14H20N2O2Forma y color:BeigePeso molecular:248.32β-D-Ribofuranuronamide, 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-
CAS:Fórmula:C18H18ClIN6O4Pureza:99%Forma y color:SolidPeso molecular:544.7308Ref: IN-DA001TN0
1gA consultar2mg51,00€5mg79,00€10mg130,00€25mg204,00€50mg248,00€100mg322,00€250mg665,00€Simvastatin Hydroxy Acid Ethyl Ester
CAS:Applications An impurity in Simvastatin (S485000). References Sankar, D. et al.: Asian J. Chem., 21, 4294 (2009); Vuletic, M. et al.: J. Pharmac. Biomed. Anal., 37, 715 (2005);Fórmula:C27H44O6Forma y color:Off-WhitePeso molecular:464.631,1-Dichloro-1-(chlorodifluoromethoxy)-2,2,2-trifluoroethane
CAS:Producto controladoApplications 1,1-Dichloro-1-(chlorodifluoromethoxy)-2,2,2-trifluoroethane is a polyhalogenated methyl ethyl ether with some anesthetic properties. References Koblin, D., et al.: Anesth. Analg., 88, 1161 (1999); Sewell, J., Sear, J.: Anesth. Analg., 102, 764 (2006);Fórmula:C3Cl3F5OForma y color:NeatPeso molecular:253.38Heptane-1,1,7-Tricarboxylic Acid Trisodium Salt
CAS:Fórmula:C10H13O6·3NaPeso molecular:229.21 3*22.99Ethyl 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylate
CAS:Fórmula:C8H10F2N2O2Pureza:>98.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:204.18Benazepril Related Compound F (tert-Butyl-3-amino-2,3,4,5-tetrahydro-2-oxo-1H-1-(3S)-benzazepine-1-acetic acid)
CAS:Lactams not elsewhere specified or includedFórmula:C16H22N2O3Forma y color:White Off-White Crystalline PowderPeso molecular:290.16304Narasin 100 µg/mL in Acetonitrile
CAS:Fórmula:C43H72O11Forma y color:Single SolutionPeso molecular:765.0317Beta-Dihydro Equilin-16,16,17-d3
CAS:Producto controladoApplications A labelled metabolite of Equilin (E592800). References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),Fórmula:C182H3H17O2Forma y color:NeatPeso molecular:271.377H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
CAS:Fórmula:C18H15N7OPureza:98%Forma y color:SolidPeso molecular:345.358Vonoprazan Fumarate
CAS:Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.Fórmula:C21H20FN3O6SPureza:≥98%Forma y color:SolidPeso molecular:461.463-O-TBS Delta5-Avenasterol (E/Z mixture)
CAS:Producto controladoApplications 3-O-TBS Δ5-Avenasterol is an intermediate in the synthesis of Δ5-Avenasterol (A794820), which is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone. References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)Fórmula:C35H62OSiForma y color:NeatPeso molecular:526.954-tert-Butyl N-(tert-Butoxycarbonyl)-L-aspartate
CAS:Fórmula:C13H23NO6Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:289.33Defluoro Nebivolol(Mixture of Diastereomers)
CAS:Producto controladoApplications Nebivolol (N387900) impurity as antihypertensive potentiator.Fórmula:C22H26FNO4Forma y color:NeatPeso molecular:387.44454-des-[(3S)-Tetrahydro-3-furanyl]-2-isopropyl Empagliflozin
CAS:Producto controladoFórmula:C22H27ClO6Forma y color:NeatPeso molecular:422.8999’-Desmethyl Granisetron
CAS:Producto controladoImpurity Granisetron EP Impurity C Applications An impurity in the synthesis of Granisetron Hydrochloride. References Nishikawa, M., et al.: Drug Metab. Pharmacokin., 19, 280 (2004), Firkusny, L., et al.: Biochem. Pharmacol., 49, 1777 (1995), Sanwald, P., et al.: Drug Metab. Dispos., 24, 602 (1996), Vanderstreene, et al.: J. Labelled Comp. Radiopharm., XLI, 3, 71 (1997),Fórmula:C17H22N4OForma y color:White To Light YellowPeso molecular:298.38Monodeschloro-Vancomycin
Fórmula:C66H76ClN9O24Forma y color:White To Off-White SolidPeso molecular:1414.84Cyclohexylamine
CAS:Producto controladoImpurity Glipizide EP Impurity B Applications Cyclohexylamine (Glipizide EP Impurity B) is a building block for pharmaceuticals that has been used for the preparation of paromomycin analogs to be used as aminogycoside antibiotics. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Rosenblum, I., Rosenblum, G.: Toxicol. Appl. Pharm., 12, 260 (1968); Hanessian, S., et. al.: J. Med. Chem., 50, 2352 (2007)Fórmula:C6H13NForma y color:NeatPeso molecular:99.17Dexamethasone-Delta17,20 21-Aldehyde
CAS:Applications A degradation and metabolic intermediate of Dexamethasone (D298800). A Dexamethasone enol aldehyde as inflammation inhibitor. References Weiss, G., et al.: J. Clin. Endocrinol. Metab., 43, 696 (1976), Hirschmann R., et al.: Steroids, 57, 579 (1992),Fórmula:C22H27FO4Forma y color:White To Off-WhitePeso molecular:374.45Naloxone Related Compound D CII (4,5α-Epoxy-3,14-dihydroxy-17-(prop-2-enyl)morphinan-7-ene-6-one)
CAS:Producto controladoAlkaloids of opium and their derivatives, salts thereof, not elsewhere specified or includedFórmula:C19H19NO4Forma y color:Light Yellow PowderPeso molecular:325.13141Erdosteine
CAS:Fórmula:C8H11NO4S2Pureza:>98.0%(GC)(T)Forma y color:White to Almost white powder to crystalPeso molecular:249.304-(4-Chlorophenyl)-2-butanone
CAS:Producto controladoApplications 4-(4-Chlorophenyl)-2-butanone has been used as a reactant in the preparation of diarylheptanoids as tumor necrosis factor-α (TNF-α) inhibitors. References Dhuru, S., et. al.: Bioorg. Med. Chem. Lett., 21, 3784 (2011)Fórmula:C10H11ClOForma y color:NeatPeso molecular:182.655-[(Dimethylamino)methyl]-2-furanmethanol
CAS:Producto controladoApplications 5-[(Dimethylamino)methyl]-2-furanmethanol is an intermediate in the synthesis of Ranitidine hydrochloride (R120000). 5-[(Dimethylamino)methyl]-2-furanmethanol is an inhibitor of monoamine oxidase B. References Lu, X., Silverman, R.B.: J. Enzym Inhib., 7, 43 (1993)Fórmula:C8H13NO2Forma y color:NeatPeso molecular:155.19Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1)
CAS:Fórmula:C31H45ClN2O5SPureza:95%Forma y color:SolidPeso molecular:593.2174Doxazosin Related Compound C (2-chloro-4-amino-6,7-dimethoxyquinazoline)
CAS:Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoiFórmula:C10H10ClN3O2Forma y color:White PowderPeso molecular:239.04615Dihydrozeatin Riboside (>90%)
CAS:Applications Dihydrozeatin Riboside can be used in biological study for cytokinins stimulated expression of stress-related proteins and transcripts in Arabidopsis thaliana with isopentenyl-transferase over-expression. References Skalak, J., et al.: J. Exp. Bot., 67, 2861-2873 (2016)Fórmula:C15H23N5O5Pureza:>90%Forma y color:NeatPeso molecular:353.37Phenylephrine Related Compound E (2-[Benzyl(methyl)amino]-1-(3-hydroxyphenyl)ethan-1-one hydrochloride)
CAS:Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFórmula:C16H17NO2·HClForma y color:Grey To White PowderPeso molecular:291.102616-Amidino-2-Naphthyl 4-Aminobenzoate Dimesylate
CAS:Fórmula:C18H15N3O2CH4O3SPeso molecular:305.34 2*96.10Naphthalene-d8
CAS:Producto controladoApplications Naphthalene-d8, is the labeled analogue of Naphthalene, a polycyclic aromatic hydrocarbons as micropollutants. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Di Toro, D., et al.: Environ. Toxicol. Chem., 19, 1971 (2000), Vines, C., et al.: Aquat. Toxicol., 51, 225 (2000), Incardona, J., et al.: Toxicol. Appl. Pharmacol., 196, 191 (2004), Junghans, M., et al.: Aquat. Toxicol., 76, 93 (2006),Fórmula:C10D8Forma y color:WhitePeso molecular:136.2221-Hydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione
CAS:Producto controladoApplications 21-Hydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione is the impurity of Dexamethasone (D298800), which is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation; it inhibits the induction of nitric oxide synthase. References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);Fórmula:C22H28O3Forma y color:NeatPeso molecular:340.46Ref: IN-DA00A17M
1g149,00€5g507,00€10g597,00€25gA consultar50mg52,00€100mg61,00€250mg77,00€500mg125,00€N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:Fórmula:C12H9F3N2O2Pureza:>95.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:270.21Norfloxacin Related Compound K (6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid)
CAS:Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFórmula:C15H16FN3O3Forma y color:Off-White SolidPeso molecular:305.11757Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, chloride
CAS:Fórmula:C21H22ClNO4Pureza:97%Forma y color:SolidPeso molecular:387.85674-Nonylphenoxyacetic Acid
CAS:Producto controladoApplications 4-Nonylphenoxyacetic Acid has the potential to act as a corrosion inhibitor for various metals and stainless steel.This compound is a contaminant of emerging concern (CECs). References DeBerry, D. er al.: Corrosion., 44, 299 (1988); Weisstuch, A. et al.: Mater. Prot. Perform., 10, 29 (1971);Fórmula:C17H26O3Forma y color:NeatPeso molecular:278.39Mirtazapine Related Compound B (1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-oxide monohydrate)
CAS:Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoiFórmula:C17H19N3O·H2OForma y color:Off-White PowderPeso molecular:281.15281Rivaroxaban Impurity 97
CAS:Fórmula:C17H16ClN3O4SForma y color:White To Off-White SolidPeso molecular:393.84Racemic Arimoclomol Maleate
CAS:Fórmula:C14H20ClN3O3·C4H4O4Forma y color:White To Off-White SolidPeso molecular:313.79 116.07Triclocarban Related Compound D Mixture (Mixture of 3,5-Bis(4-chlorophenyl)-1-(3,4-dichlorophenyl)biuret and 1,5-Bis(4-chlorophenyl)-3-(3,4-dichlorophenyl)biuret)
Ureines and their derivatives; salts thereofFórmula:C20H13Cl4N3O2Forma y color:PowderPeso molecular:466.97619Decanoic Acid
CAS:Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.Fórmula:C10H20O2Pureza:98.59%Forma y color:Crystalline Solid SolidPeso molecular:172.26Ethyl Lauroyl Arginate Hydrochloride
CAS:Fórmula:C20H40N4O3·HClPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:421.02Metformin Impurity 2 Hemi-Sulfate (Guanylurea Hemi-Sulfate)
CAS:Fórmula:C2H6N4O·5H2SO4Forma y color:White To Off-White Solid SolidPeso molecular:102.10 0.5*98.07