Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Productos de "Sales y derivados de API"
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Polyvinylpyrrolidone K 90 Average Molecular Wt. 360000
CAS:Fórmula:(C6H9NO)nForma y color:White to Almost white powder to crystal8-Oxoadenosine
CAS:Fórmula:C10H13N5O5Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:283.24Prucalopride-13C-d3
CAS:Fórmula:C1713CH23D3ClN3O3Forma y color:White To Off-White SolidPeso molecular:371.88Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
CAS:Fórmula:C17H19ClN2Pureza:95%Forma y color:SolidPeso molecular:286.7991600000001Diclofenac EP Impurity F
CAS:Fórmula:C14H10Cl3NOForma y color:White To Off-White SolidPeso molecular:314.59(S)-N-Phenyl-2-pyrrolidinecarboxamide
CAS:Fórmula:C11H14N2OPureza:98%Forma y color:SolidPeso molecular:190.2417succimimidyl-4-azidobutyrate
CAS:Fórmula:C8H10N4O4Pureza:95%Forma y color:SolidPeso molecular:226.18940000000003Diphenhydramine Related Compound [3-(Benzyhdryloxy)propane-1,2-diol]
CAS:Fórmula:C16H18O3Forma y color:Colorless LiquidPeso molecular:258.32Imperatorin
CAS:Fórmula:C16H14O4Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:270.28Naftifine N-Oxide (~90%)
Producto controladoApplications Naftifine N-Oxide is an impurity or metabolite of Naftifine Hydrochloride (N213100), an allylamine antifungal agent. References Georgopoulos, A., et al.: Antimicrob. Ag. Chemother., 19, 386 (1981); Meingassner, J.C., et al.: J. Invest. Dermatol., 77, 444 (1981); Paltauf, F., et al.: Biochim Biophys. Acta, 712, 268 (1982); Aggarwal, D., et al.: J. Pharm. Pharmacol., 56, 1509 (2004)Fórmula:C21H21NOPureza:~90%Forma y color:NeatPeso molecular:303.397trans-4-(Aminomethyl)cyclohexanecarboxylic Acid
CAS:Fórmula:C8H15NO2Pureza:>98.0%(GC)(T)Forma y color:White to Almost white powder to crystalPeso molecular:157.21Methoxymethylguanine
CAS:Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFórmula:C7H9N5O2Forma y color:Light Yellow PowderPeso molecular:195.183-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
CAS:Producto controladoImpurity Famotidine EP Impurity D Stability Hygroscopic Applications 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity in the synthesis of Famotidine (F102250) histamine H2-receptor antagonist. Antiulcerative. References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),Fórmula:C8H13N5OS2Forma y color:White To Light YellowPeso molecular:259.35Deflazacort-d3 (Major)
CAS:Producto controladoFórmula:C25H28D3NO6Forma y color:NeatPeso molecular:444.54rac Mono(3,5,5-trimethylhexyl) Phthalate
CAS:Applications Phthalate metabolite. References Larsen, S., et al.: Toxicol., 169, 37 (2001), Silva, M., et al.: J. Anal. Toxicol., 29, 819 (2005), Silva, M., et al.: Arch. Toxicol., 79, 647 (2005),Fórmula:C17H24O4Forma y color:White To Off-WhitePeso molecular:292.37Abamectin B1b (~90%)
CAS:Producto controladoFórmula:C47H70O14Pureza:~90%Forma y color:NeatPeso molecular:859.054-Methylaminoantipyrine Hydrochloride
CAS:Fórmula:C12H15N3O·ClHForma y color:Light Orange Colour To Light BrownPeso molecular:253.73Bupropion Hydrochloride Related Compound C (1-(3-chlorophenyl)-2-hydroxypropan-1-one)
CAS:Aromatic ketone-alcohols and ketone-aldehydes, nesoiFórmula:C9H9O2ClForma y color:LiquidPeso molecular:184.02911Rivaroxaban N-acyl glycolic acid ((S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C24H21Cl2N3O7S2Forma y color:Off-White SolidPeso molecular:597.0198S-(2-Carboxyethyl)-L-cysteine
CAS:Fórmula:C6H11NO4SPureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:193.2210alpha-Methoxy-1-methyl-9,10-dihydrolysergol
CAS:Producto controladoImpurity Nicergoline EP Impurity C Applications 10α-Methoxy-1-methyl-9,10-dihydrolysergol is a nicergoline (N394550) metabolite that has been shown to have antioxidant activity, preventing glutathione (GSH) depletion and lipid peroxidation; thus it has shown potential as treatment of neuroleptic-induced side effects. References Vairetti, M., et. al.: Eur. J. Pharmacol., 453, 69 (2002)Fórmula:C18H24N2O2Forma y color:White To Off-WhitePeso molecular:300.40Di-Docosahexaenoyl (C22:6)-bis(monoacyl-gylcerol) Phosphate
CAS:Fórmula:C50H75O10PPeso molecular:867.11Diclofenac Sodium Salt
CAS:Producto controladoFórmula:C14H10Cl2NO2·NaForma y color:White To BeigePeso molecular:318.13(1S, 4R)-Camphor Sulfonic Acid Methyl Ether
CAS:Fórmula:C11H18O4SForma y color:White To Off-White SolidPeso molecular:246.33Rivaroxaban Impurity 87
CAS:Fórmula:C18H20ClN3O4SForma y color:White To Off-White SolidPeso molecular:409.894-(Difluoromethoxy)-3-hydroxybenzaldehyde
CAS:Fórmula:C8H6F2O3Pureza:>98.0%(GC)Forma y color:White to Orange to Green powder to crystalPeso molecular:188.13N,N,N',N'-Bis(tetramethylene)-O-(N-succinimidyl)uronium Hexafluorophosphate
CAS:Fórmula:C13H20F6N3O3PPureza:>98.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:411.291,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS:Fórmula:C52H100NO8PPureza:98%Forma y color:SolidPeso molecular:898.3261Streptomycin Sulfate
CAS:Fórmula:C21H39N7O12H2SO4Pureza:>95.0%(T)(N)Forma y color:White to Light yellow powder to crystalPeso molecular:728.692-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-Thiazolecarboxylic Acid Ethyl Ester
CAS:Fórmula:C18H22N2O4SForma y color:NeatPeso molecular:362.44N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(2-propen-1-yloxy)carbonyl]-L-lysine
CAS:Fórmula:C25H28N2O6Pureza:98%Forma y color:SolidPeso molecular:452.4996b-Alanine, N-(aminoiminomethyl)-
CAS:Fórmula:C4H9N3O2Pureza:98%Forma y color:SolidPeso molecular:131.13315999999998(1R,2S,5R)-Menthol-hydroxy-[1,3]-oxathiolane-carboxylate (Mixture of diastereomers)
CAS:Producto controladoFórmula:C14H24O4SForma y color:NeatPeso molecular:288.40o-Toluenesulfonamide-d7
CAS:Producto controladoApplications o-Toluenesulfonamide-d7 is the isotope labelled analog of o-Toluenesulfonamide (T535880); a methylated sulfonamide and a major impurity of Saccharin (S080800). Studies suggest that o-Toluenesulfonamide has potential mutagenic activity. References Stavric, B. et al.: J. Assoc. Offic. Anal. Chem., 57, 678 (1974); Ashby, J. et al.: Food Cosm. Toxicol., 16, 95 (1978); Eckhardt, K. et al.: Toxicol. Lett., 7, 51 (1980)Fórmula:C7D7H2NO2SForma y color:NeatPeso molecular:178.26Triprolidine Hydrochloride Monohydrate
CAS:Fórmula:C19H22N2·HCl·H2OPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:332.88Nα-(tert-Butoxycarbonyl)-N1-formyl-L-tryptophan
CAS:Fórmula:C17H20N2O5Pureza:>98.0%(T)Forma y color:White to Light gray to Light yellow powder to crystalPeso molecular:332.36Iopromide Related Compound A (5-Amino-N1,N3-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-N1-methylisophthalamide)
CAS:Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereofFórmula:C15H20I3N3O6Forma y color:White Crystalline PowderPeso molecular:718.84863DL-threo-beta-(3,4-Methylenedioxyphenyl)serine Acetate Salt
CAS:Producto controladoFórmula:C12H15NO7Forma y color:NeatPeso molecular:285.254-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide
CAS:Producto controladoApplications 4-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide is an impurity of Lenvatinib (L329400), CAS# 417716-92-8.4-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide is also used in pharmaceutical studies with an analytical role as a reference standard in an HPLC method for analyzing Lenvatinib or its salt, allowing a strong specificity, accuracy, precision, and high sensitivity. References Jia, Huijuan., CN 107305202, (2016)Fórmula:C17H14ClN3O3Forma y color:NeatPeso molecular:343.76(2R,3R)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol
CAS:Fórmula:C15H14O7Pureza:98%Forma y color:SolidPeso molecular:306.26752-(1-Piperazinyl)pyrimidine-d8
CAS:Producto controladoApplications Labelled 2-(1-Piperazinyl)pyrimidine, the major metabolite of Tandospirone (T006430). References Goa, K., et al.: Drugs, 32, 114 (1986); Lamberg, T., et al.: Clin. Pharmacol. Ther., 63, 640 (1998); Niwa, T., et al.: Biol. Pharm. Bull 28, 1711 (2005); Natsui, K., et al.: Eur. J. Drug Metab. Pharmacokinet., 32, 233 (2007);Fórmula:C8H4D8N4Forma y color:Off White To Light YellowPeso molecular:172.26Ref: 4Z-C-272
Producto descatalogado1-Bromo-3-(4-bromophenoxy)benzene
CAS:Producto controladoFórmula:C12H8Br2OForma y color:NeatPeso molecular:328.00N-Nitroso Phenylephrine (1mg/mL in methanol)
CAS:Producto controladoFórmula:C9H12N2O3Forma y color:ColourlessPeso molecular:196.203S(-)-RACLOPRIDE L-TARTRATE
CAS:Fórmula:C15H20Cl2N2O3Pureza:95%Forma y color:SolidPeso molecular:347.2369Mycophenolate Mofetil-d4
CAS:Fórmula:C23H27D4NO7Forma y color:White To Off-White SolidPeso molecular:437.53Ref: 4Z-M-166
Producto descatalogado
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