Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Productos de "Sales y derivados de API"
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Methyltetrazine-amido-PEG3-Alkyne
Fórmula:C20H25N5O4Pureza:>95.0%(HPLC)(qNMR)Forma y color:Red to Dark red to Dark purple powder to crystalPeso molecular:399.45Deschloro-N-ethyl-ketamine Hydrochloride
CAS:Producto controladoApplications Deschloro-N-ethyl-ketamine Hydrochloride is a derivative of Ketamine (K165300), an anesthetic agent and used as a depressant. References Sass, W.C., et al.: Anal. Profiles Drug Subs., 6, 297 (1977), Reich, D.L., et al.: Can. J. Anaesth., 36, 186 (1989),Fórmula:C14H19NO·HClForma y color:Off White SolidPeso molecular:253.80Tyrosol Glucuronide
CAS:Stability Hygroscopic Applications Tyrosol Glucuronide is a derivative of tyrosol (T947800), which is phenolic antioxidant. References Perez-Trujillo, M., et al.: J. Agric. Food Chem., 58, 9129 (2010), Gregus, P., et al.: J. Pharm. Biomed. Anal., 53, 674 (2010),Fórmula:C14H18O8Forma y color:Off White SolidPeso molecular:314.29N-Carbamoyl-2-methylbenzenesulfonamide (N-(Aminocarbonyl)-2-methylbenzenesulfonamide)
CAS:Fórmula:C8H10N2O3SN-(p-Toluoyl)glycine
CAS:Fórmula:C10H11NO3Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:193.204-Methoxybenzyl 3-Chloromethyl-7-(2-phenylacetamido)-3-cephem-4-carboxylate
CAS:Fórmula:C24H23ClN2O5SPureza:>98.0%(N)Forma y color:White to Orange to Green powder to crystalPeso molecular:486.975-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-, (6R-cis)-
CAS:Fórmula:C16H17N3O7S2Pureza:98%Forma y color:SolidPeso molecular:427.4521Orphenadrine Related Compound A ((RS)-N,N-dimethyl-2-[(3-methylphenyl)-phenylmethoxy]ethanamine citrate) (AS)
Amino-alcohols, other than those containing more than oFórmula:C18H23NO·C6H8O7Forma y color:White Crystalline PowderPeso molecular:461.55-Hydroxyindole-3-acetic Acid-D5
CAS:Producto controladoApplications 5-Hydroxyindole-3-acetic Acid-D5 is a labelled analogue of 5-Hydroxyindole-3-acetic Acid (H953605). 5-Hydroxyindole-3-acetic Acid is an impurity of Chlorpheniramine (C424300), a histamine H1 receptor antagonist that is used to treat allergy symptoms. References Popa, V.: CHEST J., 78, 442 (1980); Snyman, J., et al.: Eur. J. Clin. Pharm., 42, 359 (1992); Sowunmi, A., et al.: Trans. Royal Soc. Trop. Med. Hyg., 91, 63 (1997)Fórmula:C102H5H4NO3Forma y color:White To BeigePeso molecular:196.21Phenylhydrazine HCl
CAS:Fórmula:C6H8N2·HClForma y color:White To Off-White SolidPeso molecular:108.14 36.46N-Dehydroxyzileuton
CAS:Producto controladoApplications N-Dehydroxyzileuton is a pharmacologically inactive metabolite of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. References Awni, W., et al.: Clin. Pharm., 29, 62 (1995); Machinist, J., et al.: Clin. Pharm., 29, 34 (1995); Remko, M., et al.: Phys. Chem. Chem. Phys., 2, 2511 (2000);Fórmula:C11H12N2OSForma y color:NeatPeso molecular:220.29L-Phenylalanine, phenylmethyl ester, 4-methylbenzenesulfonate (1:1)
CAS:Fórmula:C23H25NO5SPureza:95%Forma y color:SolidPeso molecular:427.5133Deoxy-Dihydroartemisinin
CAS:Fórmula:C15H24O4Forma y color:White To Off-White SolidPeso molecular:268.35Bendamustine Related Compound F (Mannitol-1-yl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H -benzimidazol-2-yl}butanoate)
CAS:Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoiFórmula:C22H33Cl2N3O7Forma y color:White SolidPeso molecular:521.16956EMD-95885
CAS:EMD-95885 is a selective antagonist of NMDA receptors containing NR2B subunits, with an IC50 of 3.9 nM. It does not interact with other sites on the NMDA receptor.Fórmula:C22H23FN2O3Forma y color:SolidPeso molecular:382.428N-Desmethyl Rosiglitazone
CAS:Producto controladoApplications A metabolite of Rosiglitazone. References Balton, G.C., et al.: Xenobiotica, 26, 6, 627 (1996), Kim, K., et al.: J. Clin. Pharmacol., 45, 941 (2005), Kirchheiner, J., et al.: Clin. Pharmacol. Ther., 80, 657 (2006), O'Maille, G., et al.: J. Pharm. Biomed. Anal., 48, 934 (2008),Fórmula:C17H17N3O3SForma y color:NeatPeso molecular:343.40Vasopressin Impurity 7 (Ditrifluoroacetate)
Fórmula:C46H64N14O13S2(C2HF3O2)Peso molecular:1085.22 : 2(114.02)Nortriptyline Hydrochloride
CAS:Fórmula:C19H22ClNPureza:98%Forma y color:SolidPeso molecular:299.8377Piperacilloic Acid-Piperacillin Dimer Disodium Salt (~85%)
Producto controladoStability Hygroscopic Applications Piperacilloic Acid-Piperacillin Dimer Disodium Salt is Piperacillin (P479950) impurity and can be obtained from it. Piperacillin (P479950) is broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial. References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);Fórmula:C46H52N10Na2O14S2Pureza:~85%Forma y color:NeatPeso molecular:1079.07Buspirone EP Impurity J
CAS:Producto controladoApplications Buspirone EP Impurity J is a derivative compound of Buspirone Hydrochloride (B689850), a non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. References Wu, Y. H., et al.: J. Med. Chem., 15, 477 (1972), Allen, L. E., et al.: Arzneim.-Forsch., 24, 917 (1974), Goa, K. L., et al.: Drugs, 32, 114 (1986),Fórmula:C34H52N6O5Forma y color:NeatPeso molecular:624.81N,N'-Carbonylbis[L-glutamic Acid]
CAS:Producto controladoApplications N,N'-Carbonylbis[L-glutamic Acid] is an impurity of the drug Carglumic Acid (C175965), which has been shown to have protective effects against ammonia intoxication and is used in the treatment of acute hyperammonemia. It has also been used to study the synthesis of urea-based inhibitors of glutamate carboxypeptidase II. References Paik, W.K. et al.: Life Sci., 15, 1189 (1974); O'Connor, J.E. et al.: Eur. J. Pediat., 148, 540 (1989); Lee, J.H. et al.: Biochem. Biophys. Res. Chem., 248, 391 (1998); Kozikowski, A., et al.: J. Med. Chem., 47, 1729 (2004);Fórmula:C11H16N2O9Forma y color:NeatPeso molecular:320.2536-Hydroxy-2-mercaptobenzimidazole
CAS:Producto controladoFórmula:C7H6N2OSForma y color:NeatPeso molecular:166.20Dorzolamide Impurity 34 HCl (Mixture of Diastereomers)
Fórmula:C14H20N2O8S3·HClForma y color:White To Off-White SolidPeso molecular:440.50 36.463-(2-Oxo-1,2-dihydro-4-quinolinyl)-DL-alanine Hydrochloride
CAS:Fórmula:C12H12N2O3·HClPureza:>98.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:268.70[1-Hydroxy-3-(methylisopentylamino)propylidene] Bisphosphonic Acid Monosodium Salt(Ibandronic Acid Impurity)
CAS:Producto controladoApplications An impurity of Ibandronic Acid (I120000)Fórmula:C9H22NNaO7P2Forma y color:NeatPeso molecular:341.2111-Oxo Fluticasone Propionate
CAS:Producto controladoImpurity Fluticasone EP Impurity F Applications 11-Oxo Fluticasone Propionate is an impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory. References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009), Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)Fórmula:C25H29F3O5SForma y color:White To Off-WhitePeso molecular:498.56Ref: 4Z-A-854
Producto descatalogado3-Quinolinecarboxylic acid,6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,monohydrochloride
CAS:Fórmula:C20H18ClF2N3O3Pureza:97%Forma y color:SolidPeso molecular:421.82502639999984Methyl Hippurate
CAS:Fórmula:C10H11NO3Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:193.20Ketotifen Fumarate
CAS:Fórmula:C19H19NOS·C4H4O4Forma y color:Off-White SolidPeso molecular:309.43 116.072,2'-[Carbonylbis(thio)]bisethanesulfonic Acid Dipotassium Salt
CAS:Producto controladoApplications 2,2'-[Carbonylbis(thio)]bisethanesulfonic Acid Dipotassium Salt is an impurity of Mesna (M225750).Fórmula:C5H8K2O7S4Forma y color:NeatPeso molecular:386.57Gemcitabine Triphosphate-13C-15N2 Tri(triethylamine) Salt
Fórmula:C15N2C8H14F2NO13P33C6H15NPeso molecular:506.12 3 101.19L-ido Miglustat HCl
CAS:Fórmula:C10H21NO4·HClForma y color:Off-White SolidPeso molecular:219.28 36.466-Chloro Voriconazole HCl
CAS:Fórmula:C16H13ClF3N5O·HClForma y color:White To Off-White SolidPeso molecular:383.76 36.46Duloxetine Related Compound F ((S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C18H19NOS·HClForma y color:Off-White PowderPeso molecular:333.09541L-tert-Leucine Methylamide
CAS:Fórmula:C7H16N2OPureza:>96.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:144.225-O-Desmethyl Donepezil
CAS:Fórmula:C23H27NO3Forma y color:White To Off-White SolidPeso molecular:365.47Palonosetron-d3 HCl
CAS:Fórmula:C19H21D3N2O·HClForma y color:White To Off-White SolidPeso molecular:299.43 36.46(2S)-2-[Butanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]-3-methylbutanoic Acid
CAS:Fórmula:C23H27N5O33-Amino-2-oxazolidinone D4 (AOZ D4)
CAS:Producto controladoFórmula:C3H4H2N2O2Forma y color:NeatPeso molecular:106.12Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS:Producto controladoApplications An impurity of Finasteride (F342000).Fórmula:C21H31NO2Forma y color:NeatPeso molecular:329.48Phenanthrene-d10
CAS:Producto controladoApplications Phenanthrene is a polycyclic aromatic hydrocarbons, an environmental pollutant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Di Toro, D. et al.: Environ. Toxicol. Chem., 19, 1971 (2000); Vines, C. et al.: Aquat. Toxicol., 51, 225 (2000); Incardona, J. et al.: Toxicol. Appl. Pharmacol., 196, 191 (2004); Junghans, M. et al.: Aquat. Toxicol., 76, 93 (2006);Fórmula:C142H10Forma y color:NeatPeso molecular:188.29[1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic Acid (3,4-Dichloroindometacin)
CAS:Fórmula:C19H15Cl2NO4N-(2-Aminoethyl)-N-benzylglycine Bis(trifluoroacetate)
CAS:Fórmula:C11H16N2O2·2C2HF3O2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:436.31Alpha-Phenyllongifolol
CAS:Producto controladoApplications α-Phenyllongifolol is an impurity in the synthesis of Longifolene (L469455) which is a constituent of black cumin seed and may exhibit anticancer and antibacterial activities. References Hajhashemi, V., et al.: Phytother. Res 18, 195 (2004); Bourgou, S., et al.: S Afr J Bot 76, 210 (2010)Fórmula:C21H30OForma y color:NeatPeso molecular:298.46
![5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-o…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00I72E.webp&w=3840&q=75)
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