Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Productos de "Sales y derivados de API"
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Stachydrine Hydrochloride
CAS:Fórmula:C7H13NO2·HClForma y color:White to Light yellow to Light orange powder to crystalPeso molecular:179.64Albendazole Impurity G
CAS:Impurity Albendazole EP Impurity G / Fenbendazole EP /Impurity B / USP Fenbendazole Related Compound B Applications Methyl [5(6)-chlorobenzimidazole-2-yl]carbamate is an impurity for Fenbendazole (F246750), an anthelmintic (Nematodes). (Albendazole Impurity H) Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),Fórmula:C9H8ClN3O2Forma y color:Off White SolidPeso molecular:225.63Tranylcypromine Related Compound A ((+/-)-cis-2-Phenylcyclopropanamine hydrochloride; cis-tranylcypromine hydrochloride)
CAS:Aromatic monoamines and their derivatives, salts thereof, nesoiFórmula:C9H11N·HClForma y color:White PowderPeso molecular:133.08915rac 3-Hydroxy-3-mercaptomethylquinuclidine
CAS:Producto controladoApplications Intermediate in the preparation of Cevimeline and respective derivatives. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFórmula:C8H15NOSForma y color:NeatPeso molecular:173.28rac-Norepinephrine-d6 HCl (rac-Noradrenaline-d6 HCl)
CAS:Fórmula:C8H5D6NO3·HClForma y color:White To Off-White SolidPeso molecular:175.22 36.465-Formyltetrahydropteroic Acid
CAS:Producto controladoImpurity Calcium Folinate Hydrate EP Impurity E Stability Unstable in Basic Solution Applications 5-Formyltetrahydropteroic Acid is an impurity of Folic Acid (F680300); a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. It also acts as a cofactor in biological reactions involving folate. References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)Fórmula:C15H16N6O4Forma y color:Light Yellow To Dark BrownPeso molecular:344.33L-689560
CAS:L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.Fórmula:C17H15Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:380.23Bis-anhydro-Daunomycinone Carboxylic Acid (~90%)
Producto controladoStability Acid Sensitive Applications Bis-anhydro-Daunomycinone Carboxylic Acid is a Daunomycinone (D193850) derivative.Fórmula:C20H12O7Pureza:~90%Forma y color:NeatPeso molecular:364.31Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide
CAS:Producto controladoImpurity Atorvastatin EP Impurity F Stability Hygroscopic Applications Atorvastatin (A791750) impurity. References Graul, A., et al.: Drugs Fut., 22, 956 (1997),Fórmula:C40H47FN3O8·CaForma y color:White To Light YellowPeso molecular:1473.71N-Nitroso-N,O-Didesmethyl Venlafaxine (Mixture of Diastereomers)
Fórmula:C15H22N2O3Peso molecular:278.35N-(Methylsulfonyl)-4-(desnitro) Nimesulide
CAS:Impurity Nimesulide EP Impurity E Applications N-(Methylsulfonyl)-4-(desnitro) Nimesulide is an impurity of Nimesulide (N477500). References Kulkarni, S., et al.: Curr. Sci., 83, 1442 (2002), Nguyen, D., et al.: J. Sep. Sci., 29, 1836 (2006), Zacharis, C., et al.: J. Pharm. Biomed. Anal., 49, 726 (2009),Fórmula:C14H15NO5S2Forma y color:NeatPeso molecular:341.403,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid
CAS:Fórmula:C10H14N2O4Pureza:99%Forma y color:SolidPeso molecular:226.2292(3RS)-3-(4-Chloro-phenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine Maleate
CAS:Fórmula:C15H17ClN2·C4H4O4Hydroxy Sulfentrazone
CAS:Fórmula:C11H10Cl2F2N4O4SForma y color:White To Off-White SolidPeso molecular:403.18Tropicamide Related Compound D (2-Phenylacetic acid)
CAS:Producto controladoPhenylacetic acid (alpha-toluic acid) and its saltsFórmula:C8H8O2Forma y color:Beige PowderPeso molecular:136.05243Oxociprofloxacin
CAS:Producto controladoApplications A metabolite of the fluorinated quinolone antibacterial Ciprofloxacin.Fórmula:C17H16FN3O4Forma y color:Beige To BrownPeso molecular:345.322-Thiouridine
CAS:Fórmula:C9H12N2O5SPureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:260.26Clarithromycin N-Oxide
CAS:Fórmula:C38H69NO14Forma y color:White To Off-White SolidPeso molecular:763.96(±)-Oxychlordane
CAS:Applications (±)-Oxychlordane is a persistent organic pollutant that has been found on plants and animals. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bachman, M.J., et. al.: Sci. Total Envir., 488, 115 (2014); Keller, J.M., et. al.: Environ. Sci. Tech., 48, 7807 (2014); Polder, A., et. al.: Sci. Total Environ., 488, 252 (2014)Fórmula:C10H4Cl8OForma y color:BeigePeso molecular:423.76Rabeprazole Related Compound C (1H-Benzimidazole-2-thiol)
CAS:Aromatic or modified aromatic heterocyclic compounds wiFórmula:C7H6N2SForma y color:White Light Yellow PowderPeso molecular:150.025171-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)
CAS:Producto controladoFórmula:C25H33N5O4S2Forma y color:NeatPeso molecular:531.69Doxapram-d5 HCl
CAS:Fórmula:C24H25D5N2O2·HClForma y color:White To Off-White SolidPeso molecular:383.55 36.46Tirofiban Impurity 50
CAS:Fórmula:C23H32N2O5SForma y color:White To Off-White SolidPeso molecular:448.58(5E)-5,6-Dideoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-1,2-O-(1-methylethylidene)-6-nitro-Alpha-D-xylo-hex-5-enofuranose
CAS:Producto controladoFórmula:C15H27NO6SiForma y color:NeatPeso molecular:345.46Tributyl(vinyl)tin
CAS:Producto controladoApplications Tributyl(vinyl)tin is used as a reagent in the palladium catalyzed synthesis of allyl and benzyl ethers. Tributyl(vinyl)tin is also a vinyl nucleophile for bromoacetylene and bromoaromatics. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Scott, W. et al.: J. Am. Chem. Soc., 108, 3033 (1986); Therrien, B. et al.: Angew. Chem. Int. Ed., 38, 405 (1999);Fórmula:C14H30SnForma y color:NeatPeso molecular:317.105-O-Trityl-2,3’-anhydrothymidine
CAS:Applications 5-O-Trityl-2,3’-anhydrothymidine (cas# 25442-42-6) is a compound useful in organic synthesis.Fórmula:C29H26N2O4Forma y color:NeatPeso molecular:466.531,4-Bis(3-chlorophenyl)-piperazine
CAS:Applications 1,4-Bis(3-chlorophenyl)-piperazine acts as a reagent in the preparation of diarylalkylene diamines and N, N’,N’’-triaryldialkylene triamines. References Mohr, R., et al.: From Eur. Pat. Appl. (1981), EP 31089 A1 19810701Fórmula:C16H16Cl2N2Forma y color:NeatPeso molecular:307.22Alprostadil (Prostaglandin E1)
CAS:Fórmula:C20H34O5Forma y color:White To Off-White SolidPeso molecular:354.49Modafinil Sulfone
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Fórmula:C15H15NO3SForma y color:White Off-White PowderPeso molecular:289.07726(Z)-7-(((R)-2-Amino-2-carboxyethyl)thio)-2-(2,3-dimethylbut-3-enamido)hept-2-enoic Acid
Producto controladoApplications (Z)-7-(((R)-2-Amino-2-carboxyethyl)thio)-2-(2,3-dimethylbut-3-enamido)hept-2-enoic Acid is an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct. References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),Fórmula:C16H26N2O5SForma y color:NeatPeso molecular:358.45(S)-4-Hydroxy Propranolol Hydrobromide
CAS:Producto controladoApplications (S)-4-Hydroxy Propranolol is the main metabolite of (S)-Propranolol (P831795). References Shwed, J., et al.: Xenobiotica, 22, 973 (1992), Fujita, K., et al.: Biol. Pharm. Bull., 22, 446 (1999), Walle, U., et al.: Drug Metab. Dispos., 30, 564 (2002),Fórmula:C16H21NO3·ClHForma y color:NeatPeso molecular:311.80N-Acetal Bromopride
CAS:Producto controladoApplications N-Acetal Bromopride is an impurity of bromopride, which is an antiemetic. References Fontaine, J., et al.: Arch. Int. Pharmacodyn. Ther., 213, 322 (1975), Lucker, P.W., et al.: Arzneim.-Forsch., 33, 453 (1983)Fórmula:C16H24BrN3O3Forma y color:Off-WhitePeso molecular:386.28Fosinopril sodium salt
CAS:Fórmula:C30H45NO7P·NaForma y color:White To Off-White SolidPeso molecular:585.661-(2-Bromoisovaleryl)urea
CAS:Fórmula:C6H11BrN2O2Pureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:223.07Kaempferide
CAS:Applications Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumour possibilities. Impurity of Icaritin (I163700). References Basabe, P. et al.: Eur. J. Med. Chem., 45, 4258 (2010); Ray, S.: Cent. Eur. J. Chem., 5, 1094 (2007);Fórmula:C16H12O6Forma y color:Light Yellow SolidPeso molecular:300.26Syrosingopine
CAS:Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.Fórmula:C35H42N2O11Pureza:99.25% - 99.78%Forma y color:SolidPeso molecular:666.71Ref: TM-TN2252
1mg66,00€5mg142,00€10mg212,00€25mg361,00€50mg543,00€100mg750,00€1mL*10mM (DMSO)202,00€CP 1282
CAS:Producto controladoApplications CP 1282 is the tautomer of the antibiotic Cefotetan (C242970) with similar degradation rates. References Koshiro, A. et al.: Chem. Pharm. Bull., 37, 1864 (1989); Naber, K. et al.: Zeitsch. Antmickrob. Antineoplast. Chemother., 2, 161 (1984);Fórmula:C17H17N7O8S4Pureza:>85%Forma y color:NeatPeso molecular:575.62L-Serine, methyl ester, hydrochloride
CAS:Fórmula:C4H9NO3Pureza:97%Forma y color:SolidPeso molecular:119.1192Ref: IN-DA00IA16
10g25,00€1kg160,00€25g25,00€5kg586,00€100g49,00€10kgA consultar25kgA consultar500g117,00€Desisobutyl Febuxostat
CAS:Producto controladoFórmula:C12H8N2O3SForma y color:Light Yellow SolidPeso molecular:260.27L-Arginine, N2-(2,4-dinitrophenyl)-
CAS:Fórmula:C12H16N6O6Pureza:95%Forma y color:SolidPeso molecular:340.292Sodium 4-Aminobenzenesulfonate Dihydrate (Sulfanilic Acid Sodium Salt Dihydrate)
CAS:Fórmula:C6H6NO3S·Na·2H2ON-(Pyrazinylcarbonyl)-L-phenylalanine
CAS:Fórmula:C14H13N3O3Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:271.28Carbofuran N,N-Dibutyl-3λ1-trisulfan-1-amine
CAS:Producto controladoFórmula:C20H32N2O3S3Forma y color:NeatPeso molecular:444.6752-Phenoxybenzeneboronic acid
CAS:Fórmula:C12H11BO3Pureza:98%Forma y color:SolidPeso molecular:214.0249Naltrexone-O-ethyl Carbonate
CAS:Producto controladoFórmula:C23H27NO6Forma y color:NeatPeso molecular:413.4642-(3-Ethoxy-4-ethoxycarbonylphenyl)acetic Acid
CAS:Fórmula:C13H16O5Pureza:>98.0%(GC)(T)Forma y color:White to Almost white powder to crystalPeso molecular:252.27Terazosin Related Compound B (1-(4-Hydroxy-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C19H24N4O5Forma y color:White PowderPeso molecular:388.17467Cytidine 5'-(trihydrogen diphosphate), P'-[2-(trimethylammonio)ethyl]ester, inner salt
CAS:Fórmula:C14H26N4O12P2Pureza:95%Forma y color:SolidPeso molecular:504.3234Ref: 4Z-E-4887
Producto descatalogadoTriethylene Glycol 2-Bromoethyl Methyl Ether
CAS:Fórmula:C9H19BrO4Pureza:>95.0%(GC)Forma y color:White to Yellow to Green clear liquidPeso molecular:271.15Maprotiline-d3 HCl
CAS:Fórmula:C20H20D3N·HClForma y color:White To Off-White SolidPeso molecular:280.43 36.463-Aminobenzoic Acid
CAS:Producto controladoImpurity Mesalazine EP Impurity D Applications 3-Aminobenzoic Acid, is a chemoattractants against Pseudomonas strains. A reactant used in the preparation of influenza neuraminidase inhibitors, inhibitors of transthyretin amyloid fibril formation and inhibitors of the protein chaperone Hsp90. References Menzella, H. et al.: J. Med. Chem., 52, 1518 (2009); Johnson, S. et al.: J. Med. Chem., 48, 1576 (2005); Parales, R.: App. Environ. Microbiol., 70, 285 (2004);Fórmula:C7H7NO2Forma y color:White To BeigePeso molecular:137.141,1'-Sulfonylbis[2-(methylthio)ethane]
CAS:Producto controladoFórmula:C6H14O2S3Forma y color:Off-White To Light YellowPeso molecular:214.377-Hydroxybenzo[a]pyrene
CAS:Producto controladoApplications 7-Hydroxybenzo[a]pyrene is a metabolite of Benzopyrene (BaP), a carcinogenic component of tobacco smoke implicated in lung cancer. References Li, F.,et al.: Environ. Toxicol. Pharmacol., 32, 373 (2011); Hayakawa, K., et al.: Polycyclic. Aromatic. Compound., 28, 382 (2008); Webb, L., et al.: Environ. Toxicol. Pharmacol., 21, 224 (2006);Fórmula:C20H12OForma y color:YellowPeso molecular:268.31Deoxy Venlafaxine
CAS:Impurity Venlafaxine EP Impurity G Applications Deoxy Venlafaxine (Venlafaxine EP Impurity G) is a Venlafaxine impurity.Fórmula:C17H27NOForma y color:Colourless To YellowPeso molecular:261.40O-Desmethyl Midostaurin
CAS:Stability Hygroscopic Applications O-Desmethyl Midostaurin is a metabolite of Midostaurin (M343760), a compound shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit. References Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Pedeboscq, S., et al.: PLoS. One., 7, 36811 (2012);Fórmula:C34H28N4O4Forma y color:NeatPeso molecular:556.61(+)-(2R,8aR)-[(8,8-Dimethoxycamphoryl)sulfonyl]oxaziridine
CAS:Fórmula:C12H19NO5SPeso molecular:289.352-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
CAS:Fórmula:C16H13N5O2Pureza:>98.0%(T)(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:307.31(4-(3-5,5-Dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzoyl)(methyl)carbamate Bicalutamide
CAS:Producto controladoApplications (4-(3-5,5-Dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzoyl)(methyl)carbamate Bicalutamide is an impurity of Bicalutamide(B382000) which is a non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal); Non-steroidal androgen receptor antagonist that binds the androgen receptor and prevents its activation. References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),Fórmula:C26H24F4N4O4SForma y color:NeatPeso molecular:564.55rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:Applications A metabolite of Tramadol. References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)Fórmula:C14H22ClNO2Forma y color:NeatPeso molecular:271.78Sodium (S)-2-amino-4-carboxybutanoate hydrate
CAS:Fórmula:C5H10NNaO5Pureza:97%Forma y color:SolidPeso molecular:187.1264
![3,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00I5DW.webp&w=3840&q=75)
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![Cytidine 5'-(trihydrogen diphosphate), P'-[2-(trimethylammonio)ethyl]ester, inner salt](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00IK5R.webp&w=3840&q=75)
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![(+)-(2R,8aR)-[(8,8-Dimethoxycamphoryl)sulfonyl]oxaziridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F4Z%2Fthumb-webp%2FC-211016.webp&w=3840&q=75)
