Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Productos de "Sulfonamidas y derivados"
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Triflumuron
CAS:Triflumuron: an insect growth regulator insecticide that blocks larvae chitin synthesis, leading to death.Fórmula:C15H10ClF3N2O3Pureza:99.92%Forma y color:SolidPeso molecular:358.7Ibuprofen Impurity 27
CAS:Fórmula:C13H16O2Forma y color:White To Off-White SolidPeso molecular:204.272-Hydroxy-5-[2-[4-(2-imino-1(2H)-pyridinyl)phenyl]diazenyl]-benzoic acid
CAS:2-Hydroxy-5-[2-[4-(2-imino-1(2H)-pyridinyl)phenyl]diazenyl]-benzoic acid (DPC) is a drug product that is used in pharmaceutical research and development. It is an impurity standard for HPLC analysis. DPC has been shown to be a metabolite of the drug product 2,6-dimethoxy-N-(3-methylphenyl)pyrimidine-4,6-diamine (DMX), which is used in the treatment of cancer. Impurities standards are important for ensuring the quality of drugs and ensuring that they are safe for human use. This product can also be synthesized from commercially available amino acids.Fórmula:C18H14N4O3Pureza:85%MinPeso molecular:334.33 g/molAceclofenac EP Impurity D
CAS:Producto controladoFórmula:C17H15Cl2NO4Forma y color:NeatPeso molecular:368.21Moexipril hydrochloride
CAS:Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment ofFórmula:C27H34N2O7·HClPureza:89.27%Forma y color:A Fine White To Off-White PowderPeso molecular:535.03rac-trans Dorzolamide Hydrochloride
CAS:Producto controladoApplications rac-trans Dorzolamide is an impurity of Dorzolamide (D535100). References Casini, A., et al.: Bioorg. Med. Chem. Lett., 13, 841 (2003), Clare, B., et al.: Bioorg. Med. Chem., 13, 2197 (2005),Fórmula:C10H17ClN2O4S3Forma y color:NeatPeso molecular:360.9Bromfenac sodium imp-B
CAS:Bromfenac sodium imp-B is an analytical standard that is used in drug development and research to measure the concentration of bromfenac in pharmaceutical products. Bromfenac sodium imp-B is a white to off-white crystalline powder with a melting point of about 230°C. It is soluble in methanol, ethanol, and acetone, but insoluble in water. Bromfenac sodium imp-B can be synthesized from the corresponding bromo acid chloride.Fórmula:C16H12BrNO2SPureza:Min. 95%Peso molecular:362.24 g/molLicogliflozin
CAS:Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).Fórmula:C23H28O7Pureza:98%Forma y color:SolidPeso molecular:416.46Brinzolamide Impurity 28 HBr
CAS:Fórmula:C11H19N3O5S3·HBrForma y color:White To Off-White SolidPeso molecular:369.47 80.91Glipizide Impurity 2
Fórmula:C24H22Cl2N2O6SForma y color:White To Off-White SolidPeso molecular:537.41Gliclazide Impurity D
CAS:Applications Gliclazide Impurity D is a manufacturing impurity of the drug Gliclazide (G409875) which is a sulfonylurea hypoglycemic agent and is used as an antidiabetic. References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),Fórmula:C15H20N2O3SForma y color:Off WhitePeso molecular:308.3959Etodolac
CAS:Etodolac (AY-24236), a pyranocarboxylic NSAID, blocks COX-1/2, reducing pain, fever, inflammation, and inhibits platelet aggregation.Fórmula:C17H21NO3Pureza:99.78% - 99.92%Forma y color:Crystalline SolidPeso molecular:287.35Aceclofenac EP Impurity H
CAS:Fórmula:C20H17Cl2NO8Forma y color:White To Off-White SolidPeso molecular:470.26Dorzolamide Impurity 7
Fórmula:C10H14N2O5S3Forma y color:White To Off-White SolidPeso molecular:338.41Nimesulide EP Impurity E
CAS:Fórmula:C14H15NO5S2Forma y color:White To Off-White SolidPeso molecular:341.41N-Nitroso Torasemide (Torsemide) EP Impurity C (N-Nitroso Torasemide (Torsemide) USP Related Compound C)
Fórmula:C15H17N5O4SPeso molecular:363.39Acetazolamide Related Compound E (5-Acetamido-1,3,4-thiadiazole-2-sulfonic acid potassium salt)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C4H4KN3O4S2Forma y color:PowderPeso molecular:260.92803N-(Prop-2-yn-1-yl)piperazine-1-sulfonamide hydrochloride
CAS:Pureza:97%Peso molecular:239.720001220703124'-Hydroxy aceclofenac
CAS:Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are produced by inflammatory cells in response to tissue injury. It is used to treat pain and inflammation. Aceclofenac is absorbed quickly from the gastrointestinal tract and has a high bioavailability. The maximum plasma concentration is reached within 1 hour after oral administration. Aceclofenac has a short half-life of about 2 hours. This drug binds to fatty acids and hepatoprotective substances, such as polymers, pyruvic transaminase, acetate extract, and humans. It also inhibits the transcription of cyclooxygenase-2 (COX-2), which produces prostaglandins that are involved in various aspects of inflammation.Fórmula:C16H13Cl2NO5Pureza:Min. 95%Peso molecular:370.18 g/molProthionamide
CAS:Prothionamide (1321-TH)is a thioamide derivative with antitubercular activity.Fórmula:C9H12N2SPureza:99.34%Forma y color:SolidPeso molecular:180.27Furosemide Acyl-β -D-glucuronide
CAS:Producto controladoApplications A metabolite of Furosemide (F865000).Fórmula:C18H19ClN2O11SForma y color:NeatPeso molecular:506.87N-(2,2,2-trifluoroethyl)piperazine-1-sulfonamide hydrochloride
CAS:Pureza:95.0%Peso molecular:283.69000244140625Aceclofenac EP Impurity B
CAS:Fórmula:C15H13Cl2NO2Forma y color:White To Off-White SolidPeso molecular:310.17Indomethacin Impurity 13
Fórmula:C22H22ClNO5Forma y color:White To Off-White SolidPeso molecular:415.872,3-Dihydroxypropyl 2-(4-Isobutylphenyl)propanoate
CAS:Producto controladoFórmula:C16H24O4Forma y color:NeatPeso molecular:280.36Ozagrel
CAS:Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement ofFórmula:C13H12N2O2Pureza:97.90% - 99.38%Forma y color:White PowderPeso molecular:228.25Flufenamic Acid Methyl Ester
CAS:Producto controladoFórmula:C15H12F3NO2Forma y color:NeatPeso molecular:295.26Torasemide EP Impurity D
CAS:Torasemide EP Impurity D is a drug product or impurity. It is an analytical standard for purity testing of torasemide. Torasemide EP Impurity D is also a metabolite of torasemide and can be found in urine as well as other tissues. It is natural, but not naturally occurring. Research and Development studies of this impurity are ongoing to determine its pharmacological activity and niche applications. Torasemide EP Impurity D has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.Fórmula:C17H22N4O3SPureza:Min. 95%Peso molecular:362.45 g/molO-Desmethyl Quinine ((R,S)-Isomer)
CAS:Fórmula:C19H22N2O2Forma y color:White To Off-White SolidPeso molecular:310.40Metribuzin
CAS:Metribuzin is a triazine herbicide.Fórmula:C8H14N4OSForma y color:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecular:214.29Brinzolamide USP Related Compound A ((S)-Brinzolamide)
CAS:Fórmula:C12H21N3O5S3Forma y color:White To Off-White SolidPeso molecular:383.50Saccharin
CAS:Applications It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing. References Taylor, J.D., et al.: Food Cosmet. Toxicol., 6, 313 (1968), Arnold, D.L., et al.: Fundam. Appl. Toxicol., 4, 674 (1984),Fórmula:C7H5NO3SForma y color:ColourlessPeso molecular:183.18Gliclazide EP Impurity D
CAS:Fórmula:C15H20N2O3SForma y color:White To Off-White SolidPeso molecular:308.40Mefenamic Acid 1,3-Butylene Glycol Esters (Mixture of Isomers)
Producto controladoFórmula:C19H23NO3Forma y color:MixturePeso molecular:626.78Bromfenac Impurity 25 DiSodium Salt
Fórmula:C15H11NO42·2NaForma y color:Yellow SolidPeso molecular:269.26 2 22.991-[[3-[2-[[(3-Ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulphonyl]-3-(trans-4-methylcyclohexyl)urea
CAS:Fórmula:C24H34N4O5SForma y color:NeatPeso molecular:490.62Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Fórmula:C14H10F3NO2Pureza:98.68%Forma y color:White To Light Yellow Crystalline PowderPeso molecular:281.23Foramsulfuron
CAS:Foramsulfuron, a postemergence sulfonylurea herbicide, selectively controls grass and certain broadleaved weeds in maize (Zea mays L.).Fórmula:C17H20N6O7SForma y color:SolidPeso molecular:452.44Acetaminophen Impurity 15
Fórmula:C16H16N2O4Forma y color:White To Off-White SolidPeso molecular:300.31Ibuprofen EP Impurity N
CAS:Fórmula:C11H14O2Forma y color:Pale Yellow Semi-Solid (Low M P )Peso molecular:178.23Acetazolamide EP Impurity C
CAS:Fórmula:C4H5N3OS2Forma y color:White To Off-White SolidPeso molecular:175.22Nimesulide EP Impurity A
CAS:Producto controladoFórmula:C13H11N3O7SForma y color:NeatPeso molecular:353.31Ibuprofen EP Impurity O
CAS:Fórmula:C13H18O2Forma y color:White To Off-White SolidPeso molecular:206.29Glibornuride (Mixture of Diastereomers)
CAS:Fórmula:C18H26N2O4SForma y color:White To Off-White SolidPeso molecular:366.48Isopropyl 2-(4-Isobutylphenyl)propanoate
CAS:Producto controladoFórmula:C16H24O2Forma y color:NeatPeso molecular:248.36Glibenclamide (Glyburide) EP Impurity A (Glibenclamide (Glyburide) USP Related Compound A)
CAS:Fórmula:C16H17ClN2O4SForma y color:White To Off-White SolidPeso molecular:368.83Tolnaftate EP Impurity D (Tolnaftate USP Related Compound D)
CAS:Fórmula:C8H11NForma y color:Brown LiquidPeso molecular:121.18Aceclofenac tert-Butyl Ester
CAS:Fórmula:C20H21Cl2NO4Forma y color:White To Off-White SolidPeso molecular:410.29Hydroflumethiazide
CAS:Producto controladoApplications Antihypertensive; diuretic. References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),Fórmula:C8H8F3N3O4S2Forma y color:NeatPeso molecular:331.29Etodolac EP Impurity C (Etodolac USP Related Compound A)
CAS:Fórmula:C16H19NO3Forma y color:Off-White SolidPeso molecular:273.33Chlortalidone (Chlorthalidone) EP Impurity C
Fórmula:C16H14ClNO5SForma y color:White To Off-White SolidPeso molecular:367.80Sulfamethoxazole Related Compound C (5-methylisoxazol-3-amine)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C4H6N2OForma y color:Light Yellow PowderPeso molecular:98.04801Dorzolamide Impurity 15 Disodium Salt (Mixture of Diastereomers)
Fórmula:C14H18N2O8S3·2NaForma y color:White To Off-White SolidPeso molecular:438.49 2*22.99Hydroflumethiazide
CAS:Fórmula:C8H8F3N3O4S2Forma y color:White To Off-White SolidPeso molecular:331.28Phenacetin Impurity 25 (Mixture of Isomers)
CAS:Fórmula:C12H9ClN2O2Forma y color:Yellow SolidPeso molecular:248.67Saccharin N-(2-acetic acid isopropyl ester)
CAS:Saccharin is a drug product that consists of saccharin N-isopropyl ester and an impurity standard. Saccharin is a synthetic sweetener that is found in the leaves of the herbaceous perennial S. dulcis, which has been used as a natural sweetener for centuries. Saccharin can be metabolized by humans to form 2-acetic acid and 4-methyl-1,2,3-thiadiazole (MTT) as a byproduct. The metabolite MTT may cause cancer in animals, but this has not been confirmed in humans. The pharmacopoeia specifies the purity of saccharin as 98% or greater. Metabolite standards are also provided for research purposes.Fórmula:C12H13NO5SPureza:Min. 95%Peso molecular:283.3 g/molHydrochlorothiazide Impurity 4
CAS:Fórmula:C7H9N3O4S2Forma y color:White To Off-White SolidPeso molecular:263.293-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine
CAS:3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is an analytical standard and a metabolite of sulfasalazine. It is used as a reference compound in the analysis of high purity sulfasalazine by HPLC. 3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is also used as an impurity in the drug product, API, and drug development. The CAS number for 3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is 1391062-34-2.Fórmula:C29H22N6O7S2Pureza:Min. 95%Peso molecular:630.65 g/molDorzolamide Impurity 4
CAS:Fórmula:C10H16N2O4S3Forma y color:White To Off-White SolidPeso molecular:324.43Acetaminophen acetate
CAS:Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.Fórmula:C10H11NO3Pureza:Min. 95%Forma y color:White PowderPeso molecular:193.2 g/molGlimepiride Impurity 11 (trans-4-Methylcyclohexyl Isocyanate)
CAS:Fórmula:C8H13NOForma y color:Colourless LiquidPeso molecular:139.20Torasemide (Torsemide) EP Impurity C (Torasemide (Torsemide) USP Related Compound C)
CAS:Fórmula:C15H18N4O3SForma y color:White To Off-White SolidPeso molecular:334.39a-Hydroxy Trimethoprim (Impurity)
CAS:Producto controladoApplications α-Hydroxy Trimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. References Dauber-Osguthorpe, P., et al.: Proteins, 4, 31, (1988); Darrell, J., et al.: J. Clin. Pathol., 21, 202 (1968); Zhanel, G., et al.: Antimicrob. Agents Ch., 44, 1089 (2000)Fórmula:C14H18N4O4Forma y color:Off White SolidPeso molecular:306.32Ibuprofen Ester Impurity (PEG400)
CAS:Fórmula:C34H50O7Forma y color:Colorless LiquidPeso molecular:570.772-(4-Ethylphenyl)-propanoic acid - Racemic
CAS:2-(4-Ethylphenyl)-propanoic acid is a supplement that is used to relieve pain and inflammation. It belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). This drug has been shown to be efficacious in the treatment of osteoarthritis, rheumatoid arthritis, and bronchitis. 2-(4-Ethylphenyl)-propanoic acid inhibits both prostaglandin synthesis and leukotriene synthesis by inhibiting cyclooxygenase 1, which converts arachidonic acid into prostaglandins, and 5-lipoxygenase, which converts arachidonic acid into leukotrienes. This drug has also been shown to inhibit COX-2 production in human monocytes. The active form of this drug is metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes,Fórmula:C11H14O2Pureza:Min. 95%Peso molecular:178.23 g/molDorzolamide Impurity 25
Fórmula:C10H13NO3S2Forma y color:White To Off-White SolidPeso molecular:259.34Brinzolamide Impurity 3
Fórmula:C13H23N3O7S4Forma y color:White To Off-White SolidPeso molecular:461.58trans-Hydroxy Glimepiride-d4
Fórmula:C24H30N4O6SD4Forma y color:White To Off-White SolidPeso molecular:510.65Nimesulide EP Impurity B
CAS:Fórmula:C13H13NO3SForma y color:White To Off-White SolidPeso molecular:263.31Ibuprofen 1,3-Butylene Glycol Esters (Mixture of Regio- and Stereoisomers)
Producto controladoFórmula:C17H26O3Forma y color:MixturePeso molecular:556.77Oxyclozanide
CAS:Oxyclozanide (Oxyclozanid) is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.Fórmula:C13H6Cl5NO3Pureza:99.28%Forma y color:White To Yellowish PowderPeso molecular:401.46
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