Fuente botánica

Deoxyshikonin and dodecyl gallate show significantly synergic antimicrobial activity with penicillin in vivo and in vitro, and can effectively reduce nasopharyngeal and lung colonization caused by different penicillin-resistant pneumococcal serotypes. Deoxyshikonin exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·, and shows cytotoxic activities. Deoxyshikonin may be a new drug candidate for wound healing and treatment of lymphatic diseases.

Pelargonidin-3-O-sophoroside is a specialized flavonoid glycoside, which is derived from certain plant sources. It is primarily isolated from various fruits and flowers where it contributes to pigmentation, specifically imparting hues such as red and pink. The compound functions through its role as a pigment by absorbing specific wavelengths of light, which can protect the plant tissues from excess UV radiation and attract pollinators. In addition to its role in pigmentation, pelargonidin-3-O-sophoroside exhibits antioxidant properties by scavenging free radicals. This can help in protecting cells from oxidative stress and potential damage. Its antioxidant activity makes it of interest in research related to oxidative stress-related conditions and in developing natural antioxidant therapies. Applications of pelargonidin-3-O-sophoroside are primarily focused on basic and applied plant research, particularly in understanding anthocyanin biosynthesis, plant breeding, and developing cultivars with desirable pigmentation traits. Additionally, due to its antioxidant properties, it is investigated in the context of dietary supplements and natural preservatives for food products, albeit primarily in research settings.

Tuberostemonine has antitussive activity, acts in part as an open-channel blocker at the crayfish neuromuscular junction; it also exhibits relatively higher intestinal permeabilities.

Wogonoside has anticoagulant, anti-inflammatory, anti-angiogenic and anticancer effects, it may exert its anti-inflammatory effect via dual inhibition of NF-κB and NLRP3 inflammasome. Wogonoside induced autophagy through the MAPK-mTOR pathway, it inhibited LTB 4 production at the concentration of 100 uM.

Tubuloside A has anti-inflammatory, antioxidative and hepatoprotective activities. Tubuloside A shows stronger free radical scavenging activities than alpha-tocopherol on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.).