APIs para investigación e impurezas

Applications BMS 833923 is an antagonist of smoothened, a key hedgehog (Hh) pathway regulator. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brechbiel, J., et. al.: Cancer Treat. Rev., 40, 750 (2014); Cortes, J., et. al.: J. Natl. Compr. Cancer Netw., 11, 10 (2013)

2,6-Dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid monomethyl ester is a metabolite of the drug 2,6-dimethyl-4-(3-nitrophenyl)pyridine. It has been shown to have an analytical purity greater than 98%. This compound is marketed as an HPLC standard and can be used as an impurity standard in the manufacture of a drug product. The CAS number for this compound is 64603-72-1.

4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carbox ylic acid sodium salt is a research and development compound that is synthesized using the drug product synthesis method. This compound belongs to the class of Impurity standards, which are used for quality control in analytical chemistry. The CAS number for this compound is 879097-59-3, and the molecular formula is C26H34N6O4S. The molecular weight of this compound is 564.49 g/mol. 4-(1-Hydroxy-1-methylethyl)-2-propyl-[1-[2'-[(1,3,5 -tris(triphenylmethyl

Trans-4-(6,8-Dibromo-3(4H)-quinazolinyl)cyclohexanol hydrochloride is a potent kinase inhibitor that has shown promising results in anticancer research. It specifically targets human kinases and induces apoptosis in cancer cells. This compound has been identified as a potential therapeutic agent for the treatment of various types of tumors, including those found in breast, lung, and prostate cancers. In addition to its medicinal properties, trans-4-(6,8-Dibromo-3(4H)-quinazolinyl)cyclohexanol hydrochloride can be detected in urine samples and serves as an important tool for researchers studying protein kinases and their inhibitors. This analog of Chinese medicine is a valuable addition to any laboratory seeking to advance cancer research through the development of new therapies.

5-Methyl Zolpidem is a zolpidem tartrate that is used for the treatment of insomnia and as a sedative. It is an intermediate in the synthesis of zolpidem tartrate, which is synthesized from 5-methyl-1-(4-methoxybenzoyl)-1H-benzo[d]imidazole with potassium t-butoxide. The synthesis starts with the conversion of 5-methyl-1-(4-methoxybenzoyl)-1H-benzo[d]imidazole to 1-(4'-methylphenyl) benzene by reaction with methyl iodide followed by hydrolysis of the ester group to form 1-(4'-methylphenyl) benzene. The next step involves a nucleophilic substitution reaction using potassium t-butoxide to produce 1-(4'-methylphenyl) benzene t-butoxide, followed by reaction with methanol

Applications An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.Environmental contaminants; Food contaminants Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),