APIs para investigación e impurezas

2S-OMPT is a protein that is expressed in the cell. It is involved in transcriptional regulation, and can be assayed using k562 cells. 2S-OMPT has been shown to be associated with cancer. It also increases resistance to chemotherapeutic agents by inhibiting cation channels or inducing apoptosis of leukemia cells. 2S-OMPT may also play an important role in intracellular calcium ion concentrations, as it binds to the extracellular domain of sphingosine kinase and inhibits its activity. This inhibition leads to decreased levels of intracellular calcium ions, which may modulate chemokine production by chemoresistant cancer cells.

Applications Diclofenac and its combination with Pitofenone and Fenpiverinium shows antispasmodic activity. References Lundstam, S., et al.: Lancet, 1, 1096 (1982), Thompson, J., et al.: Br. Med. J., 299, 1140 (1989), Marthak, K., et al.: Curr. Med. Res. Opi.,12, 366 (1991),

Ciprofibrate-o-β-glucuronide is the major metabolite of ciprofibrate in humans. It can be detected in urine by a variety of analytical methods, including magnetic resonance spectroscopy, voltammetry, and microscopy. Ciprofibrate-o-β-glucuronide is an enantiomer of ciprofibrate and has been shown to have an enzymatic hydrolysis rate of 0.07% per hour. This hydrolysis process is catalyzed by cytochrome P450 enzymes. Ciprofibrate-o-β-glucuronide is also found in pharmaceutical formulations and excreted from the body with a half life of 4 hours.

Desogestrel Related Compound A is a synthetic impurity standard. It is the metabolite of desogestrel, which belongs to the drug class progestins and is used for contraception. Desogestrel Related Compound A is used as a research and development or impurity standard for pharmacopoeia-grade drugs or custom synthesis with high purity. The CAS number for this product is 201360-82-9.

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

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5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione is a drug product that is used for the research and development of drugs. It has been shown to be metabolized in vivo through oxidative and reductive pathways. 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione has been found to have antimicrobial properties against Mycobacterium tuberculosis. This compound was also shown to inhibit the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes, which maintain the integrity of bacterial DNA.