APIs para investigación e impurezas

Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity>. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.

Applications A metabolite of Androstenedione (A637550). References Gazdar, A., et al.: Cancer Res., 50, 5488 (1990), Levesque, J., et al.: Steroids, 70, 305 (2005), Lootens, L., et al.: Drug Metab. Dispos., 37, 2367 (2009),

Impentamine dihydrobromide (IMB) is a research and development drug product that has been synthesized for the treatment of epilepsy. IMB is an impurity standard for impentamine, a synthetic drug that inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide is a metabolite of impentamine, which inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide binds to acetylcholinesterase by competitive inhibition and causes an accumulation of acetylcholine in the synaptic cleft. This accumulation leads to increased neurotransmission at nerve terminals, because acetylcholine is necessary for neurotransmitter release.

7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-(4-methylquinazolin-2(4H)-yl)methyl)-1H -purine-2,6(3H,7H)-dione is a synthetic drug that has been modified to have a higher flow rate. It is used in the synthesis of other drugs. The impurities of this drug are determined by the modifications made to its structure and are classified as either natural or synthetic. Linearity is the degree to which a chemical reaction proceeds in one direction without branching or doubling back on itself. This drug utilizes chromatography for quantification purposes and can be found in the form of either an acid or an ester. Formic acid and acetonitrile are two solvents that can be utilized for this drug's elution from

4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-pentan-3 -yl-1,2,4-triazol-3-one is a synthetic drug product. It has not been evaluated in humans or animals. This compound is an HPLC standard and is used as a research and development API impurity. The CAS number for this drug is 161532-65-6. The molecular weight of the drug substance is 681.3 g/mol with a purity of 99%.

(Alphas)-N,N,alpha-trimethyl-3-(4-nitrophenoxy)benzenemethanamine is a drug product that has been synthesized for research and development purposes. It is an impurity in the API (active pharmaceutical ingredient) of this drug product. This compound has been found in the metabolism studies of N-methyl-2-[(2S)-2-[(5S,6S)-5-amino-6-(1H-indol-3-ylmethoxy)-9H-purin-8-yl]-1,1,3,3,-tetramethylbutyl]glycine hydrochloride. The CAS number for this compound is 1346242-32-7.

Stability Hygroscopic Applications A partially reversible gastric proton pump inhibitor. References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993), Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994), Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

Acetamido-5-benzylthio-1,3,4-thiadiazole is an impurity that is found in the drug product acetamido-5-(2,6-dichlorobenzyl)thio-1,3,4-thiadiazole. It has been used as an analytical standard for HPLC and as a pharmacopoeia impurity standard. Acetamido-5-benzylthio-1,3,4-thiadiazole is also a metabolite of acetamido-5-(2,6 dichlorobenzyl)thio-1,3,4 thiadiazole. This compound has been detected in natural sources such as plants and animals. Acetamido-5-(2,6 dichlorobenzyl)thio 1,3,4 thiadiazole can be synthesized by reacting 2 chloroacet

3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol is a synthetic intermediate. It is metabolized from the drug product 3-[4-(2-Methoxyethyl)phenoxy]propionic acid and may be used as an impurity standard for this compound. This chemical is a high purity, pharmacopoeia grade material that is suitable for use in drug development and pharmaceutical research. 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol has a natural origin and can be produced synthetically or through biotransformation of other compounds.

Nascopine is an analog of nifedipine that acts as a potent inhibitor of protein kinases. It has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in Chinese hamsters. Nascopine is an anticancer drug that works by blocking the activity of kinases, which play a crucial role in cancer cell proliferation and survival. This drug has been found to be effective against a wide range of cancers, including breast, prostate, and lung cancer. In addition, Nascopine has been found in urine samples from cancer patients undergoing treatment with this drug. Its unique mechanism of action makes it a promising candidate for further development as an anticancer therapy.