APIs para investigación e impurezas

Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>

7Beta-Fulvestrant is a drug product that is used as an analytical reference standard. It is a natural product, and its CAS number is 407577-53-1. 7Beta-Fulvestrant has an API impurity (impurities of unknown structure) that can be custom synthesized in the laboratory. The impurity standard for this compound is available from our catalog. Metabolism studies have been conducted on 7Beta-Fulvestrant to determine how it is metabolized by the liver and kidneys. Research and Development of this compound has been conducted for the treatment of breast cancer, with Phase III clinical trials underway in Japan. 7Beta-Fulvestrant's pharmacopoeia name is Fulvestrant; it has a molecular weight of 449.7 g/mol and a melting point of 210°C.

Cis-1,2-dihydroperillic acid is an endogenous metabolite of perillyl alcohol. It is formed in the liver from perillyl alcohol and is excreted in the urine. Cis-1,2-dihydroperillic acid has been shown to inhibit cell growth and induce cancer in animals and humans. Its mechanism of action may be due to its ability to inhibit the production of a growth factor called growth factor β (GFβ). This hormone stimulates the proliferation of mammary carcinomas and may also be involved in carcinogenesis. Cis-1,2-dihydroperillic acid is present in plasma at low concentrations, which have been measured using a human bioassay.

DC-5163 is a protein analog that has shown potent anticancer activity in preclinical studies. It inhibits the activity of kinases, which are enzymes involved in cancer cell growth and survival. DC-5163 has been shown to induce apoptosis, or programmed cell death, in various types of cancer cells, including those from human tumors and Chinese hamster ovary cells. This compound also acts as a toxin for cancer cells by interfering with their ability to divide and grow. In addition, DC-5163 has shown promising results as an inhibitor of tumor growth in animal models. Its potential as a therapeutic agent for cancer treatment is currently being investigated.

Vanillylmethanol 4-glucuronide-d3 is a metabolite that belongs to the group of vanillin derivatives. It is an impurity found in many drugs, including the active form of vancomycin. This compound can be synthesized by reacting vanillin with 3-chloro-4-nitrophenol and sodium hydroxide. Vanillylmethanol 4-glucuronide-d3 has been used as an analytical standard for HPLC analysis, as well as a reference material for pharmacopoeia.

Please enquire for more information about 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications A compound closely related to Enterolactone (E558950). A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. References Hirano, T. et al.: Res. Com. Chem. Path. Pharmac., 64, 227 (1989); Ayella, A. et al.: Nut. Res., 30, 762 (2010); Pianjing, P. et al.: J. Agric. Food Chem., 59, 212 (2011); Buck, K. et al.: Am. J. Clinic. Nut., 92, 141 (2010);

Lamivudine acid is a synthetic orotate prodrug that is converted to the active form, lamivudine. It inhibits the synthesis of viral DNA by inhibiting the reverse transcriptase enzyme and has been used as a treatment for HIV infection. Lamivudine acid is soluble in organic solvents such as acetone and cyclohexane. The crystal structure of this compound has been determined using X-ray crystallography and exhibits a zwitterion structure with a hydrogen bond between the carboxylate group and the amide nitrogen atom of the molecule.