Información del producto
Nombre:25-O-Deacetyl rifabutin
Sinónimos:
- 25-O-Deacetyl-1',4-didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxorifamycin XIV25-Hydroxy rifabutin25-O-Deacetylrifabutin
Marca:Biosynth
Descripción:25-O-Deacetyl rifabutin is an antibiotic derivative, which is sourced from the semi-synthetic modification of rifabutin, a compound originally derived from the fermentation of the bacterium Amycolatopsis mediterranei. This derivative works by inhibiting bacterial RNA synthesis. It achieves this by specifically targeting the DNA-dependent RNA polymerase enzyme, which is essential for bacterial transcription. The mechanism involves binding to the beta-subunit of the polymerase, thereby blocking the elongation of the RNA chain, which ultimately leads to the death of the bacterial cell.
The primary applications of 25-O-Deacetyl rifabutin lie in its potential use as an anti-tubercular agent. Given the increasing prevalence of resistant Mycobacterium tuberculosis strains, derivatives of rifabutin are being extensively researched for their potential to combat multi-drug resistant forms of tuberculosis. Moreover, its structure-activity relationship is also explored for optimizing efficacy and minimizing resistance development. Studies on 25-O-Deacetyl rifabutin are ongoing to ascertain its pharmacokinetic properties and to evaluate its viability as a therapeutic agent within the broader context of infectious disease control.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:804.97 g/mol
Fórmula:C44H60N4O10
Pureza:Min. 95%
Color/Forma:Purple Powder
Consulta técnica sobre: 25-O-Deacetyl rifabutin
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