4-Cyano-3-fluorophenylboronic acid (contains varying amounts of Anhydride)
CAS:
Ref. 3D-FC46550
Información del producto
Nombre:4-Cyano-3-fluorophenylboronic acid (contains varying amounts of Anhydride)
Marca:Biosynth
Descripción:4-Cyano-3-fluorophenylboronic acid is a boronic acid that is used in the treatment of primary aldosteronism. This drug inhibits the activity of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1), which converts cortisol to cortisone. It also blocks mineralocorticoid receptors, leading to decreased levels of aldosterone and increased levels of renin. 4-Cyano-3-fluorophenylboronic acid is metabolized by cytochrome P450 enzymes, with the formation of anhydride as one of its metabolites. The pharmacological effects of 4-cyano-3-fluorophenylboronic acid are due to its ability to inhibit 11βHSD1, inhibiting renal reabsorption of sodium and water.
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Propiedades químicas
Peso molecular:164.93 g/mol
Fórmula:C7H5BFNO2
Pureza:Min. 95%
InChI:InChI=1S/H3N/h1H3
Clave InChI:InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
SMILES:N#Cc1ccc(B(O)O)cc1F