R-(-)-Manidipine
CAS:
Ref. 3D-FM25012
Información del producto
Nombre:R-(-)-Manidipine
Sinónimos:
- (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester (-)-Manidipine
Marca:Biosynth
Descripción:R-(-)-Manidipine is a chiral compound that is metabolized in the body to form two enantiomers, (+)- and (-)-manidipine. The pharmacokinetic study of R-(-)-Manidipine was conducted by comparing the plasma concentrations of the racemic mixture with those of the individual enantiomers. The diastereomeric ratios were determined by analyzing plasma samples using a mass spectrometer and reaction monitoring. The pharmacokinetic study showed that both enantiomers have antihypertensive activity, but (-)-manidipine has higher potency than (+)-manidipine.
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Propiedades químicas
Peso molecular:610.7 g/mol
Fórmula:C35H38N4O6
Pureza:Min. 95%