CAS 114-49-8: Bromhydrate de scopolamine
Description :
Bromhydrate de scopolamine est un alcaloïde tropane dérivé de plantes de la famille des Solanacées, en particulier de la plante de belladone. C'est une poudre cristalline blanche à blanc cassé qui est soluble dans l'eau et l'alcool, ce qui la rend adaptée à diverses formulations pharmaceutiques. La substance agit principalement comme un agent anticholinergique, bloquant l'action de l'acétylcholine dans le système nerveux, ce qui la rend efficace pour traiter le mal des transports, les nausées et les vomissements. Bromhydrate de scopolamine est également utilisé dans des contextes préopératoires pour réduire la salivation et les sécrétions. Ses effets pharmacologiques incluent la sédation, l'amnésie et la relaxation musculaire, mais il peut également provoquer des effets secondaires tels que la sécheresse buccale, la vision floue et la somnolence. En raison de son potentiel d'abus et du risque d'effets secondaires graves, son utilisation est soigneusement surveillée dans les milieux cliniques. Comme pour tout médicament, il est essentiel d'utiliser Bromhydrate de scopolamine sous la direction d'un professionnel de la santé pour garantir sécurité et efficacité.
Formule :C17H21NO4·BrH
InChI :InChI=1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
Code InChI :InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N
SMILES :CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br
Synonymes :- (-)-Scopolamine bromide
- (-)-Scopolamine, HBr
- (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
- 3-Oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]nonane, benzeneacetic acid deriv.
- 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
- 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
- Beldavrin
- Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide (1:1), (αS)-
- Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, (αS)-
- Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
- Voir plus de synonymes
Trier par
8 produits concernés.
Scopolamine HBr (Hyoscine HBr)
CAS :Formule :C17H21NO4·HBrCouleur et forme :White To Off-White SolidMasse moléculaire :303.36 80.91Scopolamine-13C, D3 Hydrobromide
CAS :Produit contrôléApplications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),Formule :C1613CH19D3BrNO4Couleur et forme :Off-WhiteMasse moléculaire :388.28Scopolamine Hydrobromide Trihydrate
CAS :Formule :C17H21NO4·HBr·3H2ODegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :438.32Scopolamine Hydrobromide Hydrate
CAS :Produit contrôléApplications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective & Neuroresearch Product. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);Formule :C17H21NO4·HBr·xH2OCouleur et forme :White SolidMasse moléculaire :384.26(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide
CAS :(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromideMasse moléculaire :438.31g/molScopolamine hydrobromide
CAS :Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions. This compound is extensively used in clinical settings for the prevention and treatment of motion sickness and postoperative nausea and vomiting. Its ability to cross the blood-brain barrier makes it effective in influencing central nervous system activities, particularly within the vestibular pathways. Additionally, it has applications in ophthalmology for pupil dilation due to its mydriatic effect. The understanding of its molecular interactions and effects on neurotransmitter pathways is crucial for advancing therapeutic uses, as well as minimizing potential side effects such as dry mouth and blurred vision.Formule :C17H21NO4·HBrDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :384.26 g/molScopolamine hydrobromide
CAS :Natural alkaloidFormule :C17H21NO4HBrDegré de pureté :≥ 95.0 % (HPLC)Couleur et forme :PowderMasse moléculaire :384.27
![(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trih…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR310495.jpg&w=3840&q=75)
