CAS: 128420-71-3

Minocycline hydrochloride dihydrate is a broad-spectrum antibiotic, which is a synthetic derivative of tetracycline. It is sourced from chemical synthesis processes and possesses potent antimicrobial properties. The mode of action involves inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This mechanism effectively disrupts bacterial growth and replication. Minocycline hydrochloride dihydrate is widely used in the treatment of various bacterial infections, including acne, respiratory tract infections, skin infections, and certain sexually transmitted infections. Due to its high tissue penetration and lipid solubility, it is particularly effective against intracellular pathogens and has been researched for use in neuroprotective and anti-inflammatory applications. While it is generally well-tolerated, its use should be guided by susceptibility testing to ensure effectiveness against specific strains. Its robust action and broad applicability make it a valuable tool in clinical and research settings for targeting resistant bacterial strains.