CAS: 183721-13-3

MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).

N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)benzamide is a peptide that has been shown to bind to the antibody and receptor. It also inhibits ion channels and can be used as a research tool for studying cell biology and pharmacology. N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)benzamide binds to the ligand by competitive inhibition. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase or conjugation with glucuronic acid. N-(9-Chloro-2-furan