CAS 474-25-9: Acide chénodésoxycholique
Description :
Acide chénodésoxycholique (CDCA) est un acide biliaire qui joue un rôle crucial dans la digestion et l'absorption des graisses alimentaires et des vitamines liposolubles dans l'intestin. C'est une poudre cristalline blanche à blanc cassé, soluble dans l'eau et dans des solvants organiques comme l'éthanol et le méthanol. Le CDCA est synthétisé dans le foie à partir du cholestérol et est un acide biliaire primaire, ce qui signifie qu'il est produit directement à partir du cholestérol plutôt que dérivé d'autres acides biliaires. Sa structure chimique présente un noyau stéroïdien avec des groupes hydroxyles à des positions spécifiques, contribuant à sa nature amphipathique, qui lui permet d'émulsifier les graisses. Le CDCA est impliqué dans la régulation du métabolisme du cholestérol et a été étudié pour son potentiel thérapeutique dans des conditions telles que les calculs biliaires et certaines maladies du foie. De plus, il peut influencer le microbiome intestinal et a des implications pour la santé métabolique. En tant que substance d'origine naturelle, il est également utilisé dans diverses formulations pharmaceutiques et compléments alimentaires.
Formule :C24H40O4
InChI :InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1
Code InChI :InChIKey=RUDATBOHQWOJDD-BSWAIDMHSA-N
SMILES :C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Synonymes :- (3Alpha,5Beta,7Alpha,8Xi,9Xi,14Xi)-3,7-Dihydroxycholan-24-Oic Acid
- (3Alpha,5Beta,7Alpha,8Xi,9Xi,14Xi)-3,7-Dihydroxycholan-24-Oicacid
- (3α,5β,7α)-3,7 Dihydroxycholan-24-oic acid
- (5Beta)-3,7-Dihydroxycholan-24-Oic Acid
- (5Beta)-3,7-Dihydroxycholan-24-Oicacid
- 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol
- 3-Alpha,7-Alpha-Dihydroxy-5-Beta-Cholan-24-Oicacid
- 3alpha,7alpha-Dihydroxy-5beta-cholanic acid
- 3α,7α-Dihydroxy-5β-cholan-24-oic acid
- 3α,7α-Dihydroxy-5β-cholanic acid
- 3α,7α-Dihydroxy-5β-cholanoic acid
- Voir plus de synonymes
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Chenodeoxycholic acid for system suitability CRS
CAS :Chenodeoxycholic acid for system suitability CRSChenodeoxycholic acid for peak identification CRS
CAS :Chenodeoxycholic acid for peak identification CRSChenodeoxycholic acid
CAS :Formule :C24H40O4Degré de pureté :≥ 98.0%Couleur et forme :White to off-white powderMasse moléculaire :392.57Chenodeoxycholic acid, 97%, from chicken
CAS :Formule :C24H40O4Degré de pureté :≥ 97.0%Couleur et forme :White or off-white powderMasse moléculaire :392.57Chenodeoxycholic acid
CAS :Formule :C24H40O4Degré de pureté :95%~99%Couleur et forme :Cryst.Masse moléculaire :392.58Chenodeoxycholic Acid
CAS :Produit contrôléImpurity Ursodeoxycholic Acid EP Impurity A Applications Chenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A) is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol. References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),Formule :C24H40O4Couleur et forme :BeigeMasse moléculaire :392.57Chenodeoxycholic acid
CAS :Produit contrôléChenodeoxycholic acid is a human primary bile acid which is also found the bile of geese. Its C-7 epimer, Ursodeoxycholic acid is found in bearâs bile. Both bile acids are used for the treatment of gallstones, although Ursodeoxycholic acid has shown superior efficacy (bearâs bile extracts are also used in Chinese medicine).Formule :C24H40O4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :392.57 g/molChenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A)
CAS :Formule :C24H40O4Couleur et forme :White To Off-White SolidMasse moléculaire :392.58Chenodeoxycholic acid
CAS :Chenodeoxycholic acidFormule :C24H40O4Degré de pureté :Loss on drying: 0.3%. (Typical Value in Batch COA)Couleur et forme : off-white powderMasse moléculaire :392.57g/molChenodeoxycholic acid
CAS :Formule :C24H40O4Degré de pureté :>98%Couleur et forme :SolidMasse moléculaire :392.57Chenodeoxycholic Acid
CAS :Formule :C24H40O4Degré de pureté :>97.0%(GC)Couleur et forme :White to Light yellow powder to crystalineMasse moléculaire :392.58Chenodeoxycholic acid
CAS :Chenodeoxycholic acid (CDCA), a bile acid, usually conjugated with either glycine or taurine, acts as a detergent to solubilize fats for intestinal absorption.Formule :C24H40O4Degré de pureté :99.70% - 99.72%Couleur et forme :White - Almost White Solid PowderMasse moléculaire :392.57Chenodeoxycholic acid
CAS :Degré de pureté :95.0%Couleur et forme :Solid, Crystalline Powder or Needles or PowderMasse moléculaire :392.5799865722656(3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid
CAS :Formule :C24H40O4Degré de pureté :%Couleur et forme :SolidMasse moléculaire :392.572Ref: IN-DA0039AV
5g21,00€10g26,00€1kg521,00€25g36,00€3kg911,00€50g52,00€100g82,00€250g149,00€500g202,00€Chenodeoxycholic Acid-d7 (Major)
CAS :Produit contrôléApplications Chenodeoxycholic Acid-d7 is a labelled analogue of Chenodeoxycholic Acid (C291900), which is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Fcilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol. In addition, Chenodeoxycholic Acid-d7 is an intermediate in synthesizing Glycochenodeoxycholic Acid-d7 Sodium Salt (G641257), which is a labelled Glycochenodeoxycholic Acid (G641255). A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972); Iser, J.H., et al.: Drugs, 21, 90 (1981); Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986); Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005)Formule :C24H33D7O4Couleur et forme :NeatMasse moléculaire :399.62Chenodeoxycholic acid
CAS :Produit contrôléChenodeoxycholic acid is a human primary bile acid which is also found the bile of geese. Its C-7 epimer, Ursodeoxycholic acid is found in bears bile. Both bile acids are used for the treatment of gallstones, although Ursodeoxycholic acid has shown superior efficacy (bears bile extracts are also used in Chinese medicine).Formule :C24H40O4Degré de pureté :Min. 98 Area-%Masse moléculaire :392.58 g/mol
