IAP
Les inhibiteurs de protéines inhibitrices de l'apoptose (IAP) sont des composés qui bloquent l'activité des IAP, une famille de protéines qui empêchent l'apoptose en inhibant les caspases et d'autres composants de la machinerie apoptotique. Les inhibiteurs d'IAP favorisent l'apoptose dans les cellules cancéreuses en neutralisant ces signaux de survie, ce qui en fait des outils importants dans la recherche sur le cancer et la thérapie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs d'IAP de haute qualité pour soutenir vos recherches en oncologie, apoptose et développement thérapeutique.
Produits appartenant à la catégorie "IAP"
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AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formule :C60H82N8O10Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :1075.36CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Couleur et forme :Lyophilized PowderMasse moléculaire :15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :48-65 KDa (reducing condition)Anti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Couleur et forme :Odour LiquidCUDC-427
CAS :CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formule :C29H36N6O4SDegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :564.7CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :40.7 kDa (predicted); 48-60 kDa (reducing condition, due to glycosylation)AZD5582
CAS :AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Formule :C58H78N8O8Degré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :1015.29CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :17.1 kDa (predicted); 38.8 kDa (reducing conditions)GDC-0152
CAS :GDC-0152 is a potent inhibitor of IAPs.Formule :C25H34N6O3SDegré de pureté :97.18% - 99.32%Couleur et forme :SolidMasse moléculaire :498.64BV6
CAS :BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formule :C70H96N10O8Degré de pureté :97.46% - 99.89%Couleur et forme :SolidMasse moléculaire :1205.57Ref: TM-T6428
1mg52,00€2mg67,00€5mg95,00€10mg153,00€25mg301,00€50mg567,00€100mg810,00€1mL*10mM (DMSO)188,00€ASTX660
CAS :Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formule :C30H42FN5O3Degré de pureté :97.81% - 98.33%Couleur et forme :SolidMasse moléculaire :539.68Ref: TM-TQ0029
1mg84,00€5mg144,00€10mg216,00€25mg432,00€50mg638,00€100mg908,00€1mL*10mM (DMSO)172,00€CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Couleur et forme :Lyophilized PowderMasse moléculaire :13.8 kDa (predicted)Anti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Couleur et forme :Odour LiquidSM-164
CAS :SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formule :C62H84N14O6Degré de pureté :97.25% - 99.92%Couleur et forme :SolidMasse moléculaire :1121.42Anticancer agent 128
CAS :Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Formule :C26H38N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.6LCL161
CAS :LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formule :C26H33FN4O3SDegré de pureté :99.13% - 99.72%Couleur et forme :SolidMasse moléculaire :500.63SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Formule :C62H85ClN14O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1157.88Anti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Couleur et forme :Odour LiquidXevinapant
CAS :Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formule :C32H43N5O4Degré de pureté :98% - 99.48%Couleur et forme :SolidMasse moléculaire :561.71Ref: TM-T6763
1mg43,00€2mg57,00€5mg93,00€10mg131,00€25mg279,00€50mg525,00€100mg745,00€200mg1.008,00€500mg1.320,00€1mL*10mM (DMSO)145,00€
