
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase
- CDK
- Arrêt du cycle cellulaire
- Chk
- c-Myc
- Dynamine
- DYRK
- Ferroptose
- HSP
- Intégrine
- Kinésine
- KSP
- LIM Kinase
- Microtubules associés
- PKC
- PLK
- Rho
- ROCK
- Wee1
Affichez 11 plus de sous-catégories
Produits appartenant à la catégorie "Cycle cellulaire/point de contrôle"
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TY-011
CAS :TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 μM. It is utilized in research focused on gastric cancer.Formule :C18H16ClN5Couleur et forme :SolidMasse moléculaire :337.81T025
CAS :T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Formule :C21H18N8Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :382.42Ref: TM-T13058
1mg143,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€500mg3.125,00€1mL*10mM (DMSO)378,00€Empesertib
CAS :Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formule :C29H26FN5O4SDegré de pureté :97.45% - 98.44%Couleur et forme :SolidMasse moléculaire :559.61Ref: TM-T8487
1mg90,00€5mg183,00€10mg275,00€25mg449,00€50mg615,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)245,00€CDK2 degrader 4
CAS :CDK2 degrader4 (compound 104) is a potent degrader of CDK2, showing promise for cancer research applications.Formule :C23H26ClN3O5Couleur et forme :SolidMasse moléculaire :459.923Adebrelimab
CAS :Adebrelimab (SHR-1316) is a humanized monoclonal antibody targeting PD-L1 with antitumor activity for the study of solid tumors.Degré de pureté :95% - 95%Couleur et forme :LiquidCHK1-IN-4 hydrochloride
CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1).Formule :C18H19BrClN7O2Degré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :480.75BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].Degré de pureté :98%Couleur et forme :Odour Solid2'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine
CAS :2'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine is a purine nucleoside analog with potential antitumor activity.Formule :C10H15N3O5Degré de pureté :96.76%Couleur et forme :SolidMasse moléculaire :257.24AT9283
CAS :AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Ref: TM-T3068
1mg47,00€2mg60,00€5mg95,00€10mg170,00€25mg299,00€50mg499,00€100mg723,00€1mL*10mM (DMSO)97,00€CCT241736
CAS :CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formule :C22H23Cl2N7Degré de pureté :96.2% - 99.88%Couleur et forme :SolidMasse moléculaire :456.37Cdk1/2 Inhibitor III
CAS :Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.Formule :C15H13F2N7O2S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :425.44Ref: TM-T14914
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€CRT-0105950
CAS :CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Formule :C21H16ClN3OSDegré de pureté :99.78% - 99.86%Couleur et forme :SolidMasse moléculaire :393.89Ref: TM-T23917
1mg65,00€5mg140,00€10mg216,00€25mg439,00€50mg707,00€100mg1.130,00€1mL*10mM (DMSO)156,00€IRE1α kinase-IN-9
CAS :IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.Formule :C24H24N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.46Isoguanine
CAS :Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis.Formule :C5H5N5ODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :151.13Vidarabine
CAS :Vidarabine is a nucleoside antibiotic from Streptomyces with antiviral properties, effective against herpes and other DNA viruses.Formule :C10H13N5O4Degré de pureté :100%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :267.24Rac1 Inhibitor F56, control peptide acetate
Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe.Formule :C74H120N18O25SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1692.94Lon-TK
Lon-TK is a glycolysis inhibitor of LTB, linked with a linker conjugate. LTB is an intelligent responsive prodrug, comprised of Lonidamine (Lon) and a PD-L1 inhibitor (BMS-1), which are connected through a thioketal linkage. It effectively inhibits glycolytic metabolism in tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK holds potential for use in photodynamic-enhanced immunotherapy research.Formule :C24H28Cl2N2O3S2Couleur et forme :SolidMasse moléculaire :527.53rel-(2S,3R)-Voruciclib hydrochloride
CAS :Rel-(2S,3R)-Voruciclib hydrochloride is an enantiomer of Voruciclib hydrochloride, an orally active cyclin-dependent kinase (CDK) inhibitor.Formule :C22H20Cl2F3NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.3CVT-313
CAS :CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.Formule :C20H28N6O3Degré de pureté :97.46% - 97.97%Couleur et forme :SolidMasse moléculaire :400.47Ref: TM-T3195
1mg44,00€2mg55,00€5mg88,00€10mg118,00€25mg208,00€50mg380,00€100mg565,00€1mL*10mM (DMSO)88,00€Prolgolimab
CAS :Prolgolimab (BCD-100) is an anti-PD-1 antibody used in melanoma research.Degré de pureté :>95%Couleur et forme :Liquid6-O-Methyl Guanosine
CAS :6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.Formule :C11H15N5O5Degré de pureté :97.50%Couleur et forme :SolidMasse moléculaire :297.27Lysidine
CAS :Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.Formule :C4H8N2Degré de pureté :98%Couleur et forme :Light Yellow To Off-White CrystallineMasse moléculaire :84.12Trifluridine
CAS :Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.Formule :C10H11F3N2O5Degré de pureté :99.39% - 99.82%Couleur et forme :White Crystalline PowderMasse moléculaire :296.2Haspin-IN-3
CAS :Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.Formule :C16H10N2O3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :278.261-Methylcytosine
CAS :1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired withFormule :C5H7N3ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :125.13MM41
CAS :MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.Formule :C44H66N10O6Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :831.06Ref: TM-T60028
1mg52,00€5mg116,00€10mg178,00€25mg293,00€50mg393,00€100mg520,00€200mg712,00€1mL*10mM (DMSO)160,00€Kira8
CAS :Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).Formule :C31H29ClN6O3SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :601.12Ref: TM-T11762L
1mg87,00€5mg202,00€10mg305,00€25mg567,00€50mg810,00€100mg1.111,00€1mL*10mM (DMSO)269,00€SCH-1473759 hydrochloride
CAS :SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463Didox
CAS :Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Formule :C7H7NO4Degré de pureté :96.85%Couleur et forme :SolidMasse moléculaire :169.13DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS :DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formule :C41H49N4O9PDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :772.82HMN-214
CAS :HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Formule :C22H20N2O5SDegré de pureté :100% - 98.63%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T2438
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg219,00€50mg350,00€100mg505,00€500mg1.121,00€1mL*10mM (DMSO)92,00€Durvalumab
CAS :Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.Degré de pureté :SDS-PAGE:97.2%;SEC-HPLC:95.3%Couleur et forme :LiquidMasse moléculaire :146.03 kDaILK-IN-2
CAS :ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5488
1mg48,00€5mg97,00€10mg128,00€25mg162,00€50mg192,00€100mg281,00€200mg408,00€1mL*10mM (DMSO)137,00€Tibremciclib
CAS :Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].Formule :C28H32F2N8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.6MLS-573151
CAS :MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formule :C21H19N3O2SDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :377.46Ref: TM-T22106
2mg35,00€5mg52,00€10mg90,00€25mg170,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€DTP3
CAS :DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formule :C26H35N7O5Couleur et forme :SolidMasse moléculaire :525.6BI-847325
CAS :BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formule :C29H28N4O2Degré de pureté :97.13% - 97.54%Couleur et forme :SolidMasse moléculaire :464.56Ref: TM-T6785
1mg49,00€5mg97,00€10mg153,00€25mg296,00€50mg445,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)97,00€CASIN
CAS :CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formule :C20H22N2ODegré de pureté :100% - 99.86%Couleur et forme :SolidMasse moléculaire :306.4Ref: TM-T3971
1mg38,00€2mg49,00€5mg74,00€10mg120,00€25mg188,00€50mg283,00€100mg435,00€500mg938,00€1mL*10mM (DMSO)74,00€Kaempferitrin
CAS :Kaempferitrin has antidepressant effects via 5-HT1A, targets HeLa cells, promotes glucose control, and boosts immune function, including NK cells.Formule :C27H30O14Degré de pureté :98% - 99.59%Couleur et forme :SolidMasse moléculaire :578.52Ref: TM-T3386
1mg50,00€5mg123,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€500mg1.483,00€1mL*10mM (DMSO)156,00€Nolatrexed
CAS :Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formule :C14H12N4OSDegré de pureté :97.91%Couleur et forme :SolidMasse moléculaire :284.34Ref: TM-T4228
1mg42,00€2mg50,00€5mg90,00€10mg148,00€25mg240,00€50mg430,00€100mg633,00€1mL*10mM (DMSO)96,00€BMH-21
CAS :BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formule :C21H20N4O2Degré de pureté :98.87% - 99.53%Couleur et forme :SolidMasse moléculaire :360.41Reozalimab
CAS :Rezilimab is a bispecific antibody that targets PD-1/PD-L1 and mediates antibody-dependent cell cytotoxicity (ADCC) in cancer research [1] [2].Degré de pureté :98%Couleur et forme :LiquidN1-Methylpseudouridine-5'-triphosphate
CAS :N1-Methylpseudouridine-5'-triphosphate is a modified nucleotide and can replace UTP in synthesis thereby improving RNA stability and reducing immunogenicity.Formule :C10H17N2O15P3Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :498.17BMS-5
CAS :BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formule :C17H14Cl2F2N4OSDegré de pureté :95.83% - 99.88%Couleur et forme :SolidMasse moléculaire :431.29Ref: TM-T4598
1mg43,00€2mg55,00€5mg84,00€10mg123,00€25mg198,00€50mg298,00€100mg444,00€1mL*10mM (DMSO)92,00€Fialuridine
CAS :Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Formule :C9H10FIN2O5Degré de pureté :99.71% - 99.90%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :372.09Ref: TM-T7655
1mg35,00€5mg74,00€10mg116,00€25mg235,00€50mg373,00€100mg562,00€500mg1.216,00€1mL*10mM (DMSO)82,00€CDK4/6-IN-24
CAS :CDK4/6-IN-24 (Compound A) is an inhibitor of CDK4/6 with broad-spectrum antitumor activity. It can effectively inhibit various cancer cells, exhibiting an IC50 in the submicromolar range.Formule :C32H41N7O3Couleur et forme :SolidMasse moléculaire :571.713Carotegrast methyl
CAS :Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formule :C28H26Cl2N4O5Degré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :569.44Ref: TM-T30751
10g9.508,00€1mg74,00€5mg160,00€10mg264,00€25mg528,00€50mg785,00€100mg1.130,00€200mg1.549,00€1mL*10mM (DMSO)170,00€1ACTA
CAS :1ACTA (IRE1αS-nitrosylation inhibitor) is a compound that helps maintain the endoplasmic reticulum stress response under conditions of nitrosative stress.Formule :C14H16N2O2Couleur et forme :SolidMasse moléculaire :244.29NRTT-IN-1
CAS :NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.Formule :C28H24FN5O5Couleur et forme :SolidMasse moléculaire :529.519PND-1186
CAS :PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5Catumaxomab
CAS :Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Degré de pureté :95%Couleur et forme :LiquidPOL1-IN-1
CAS :POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂,IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。Formule :C21H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.42Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activationFormule :C76H121N19O25SDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :1732.95CAF-382
CAF-382 (compound B1), an analog of SNS-032, functions as a CDKL5 and pan-CDK inhibitor, exhibiting modest inhibitory activity against GSK3α/β with an affinityFormule :C16H22N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.5PD-L1-IN-3
CAS :PD-L1-IN-3 is a PD-1/PD-L1 inhibitor for the study of tumors and immune diseases.Formule :C19H15ClFN2OSDegré de pureté :99.47%Couleur et forme :SoildMasse moléculaire :373.85DHX9-IN-2
CAS :DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.Formule :C18H16ClN3O3S2Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :421.92β-glycosidase-IN-1
CAS :β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33Orotic acid
CAS :Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.Formule :C5H4N2O4Degré de pureté :99.42%Couleur et forme :Crystals Physical Description White Crystals Or Crystalline Powder (Ntp 1992)Masse moléculaire :156.1IDD388
CAS :IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formule :C16H12BrClFNO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :416.63BTYNB
CAS :BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formule :C12H9BrN2OSDegré de pureté :99.91% - ≥95%Couleur et forme :SolidMasse moléculaire :309.18Ref: TM-T9033
5mg48,00€10mg63,00€25mg93,00€50mg136,00€100mg198,00€200mg309,00€500mg563,00€1mL*10mM (DMSO)50,00€Orbofiban TFA
CAS :Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormule :C19H24F3N5O6Degré de pureté :97.45% - 98.43%Couleur et forme :SolidMasse moléculaire :475.42PLN-1474
CAS :PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formule :C24H37N3O4Degré de pureté :99.25%Couleur et forme :SoildMasse moléculaire :431.57Ref: TM-T60101
1mg52,00€5mg111,00€10mg180,00€25mg305,00€50mg439,00€100mg612,00€1mL*10mM (DMSO)124,00€RdRP-IN-6
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM.Formule :C41H67N8O7PSi2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :871.16Firategrast
CAS :Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5Ref: TM-TQ0291
1mg47,00€5mg87,00€10mg140,00€25mg283,00€50mg464,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€Pacmilimab
CAS :Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.Degré de pureté :95% - 95%Couleur et forme :LiquidNUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formule :C25H30N6OCouleur et forme :SolidMasse moléculaire :430.545MLN8054
CAS :MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86Ref: TM-T6315
1mg52,00€2mg71,00€5mg88,00€10mg127,00€25mg233,00€50mg376,00€100mg567,00€1mL*10mM (DMSO)93,00€2,5-Di-tert-butyl-1,4-benzoquinone
CAS :2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31AS-0141
CAS :AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM),具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶,在细胞周期中对 DNA 复制的启动至关重要。Formule :C21H22F3N5O4Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :465.43DI-87
CAS :DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Formule :C23H30N6O3S2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :502.65Levoleucovorin Calcium
CAS :Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formule :C20H21N7O7·CaDegré de pureté :98.46% - ≥98%Couleur et forme :White Crystalline PowderMasse moléculaire :511.5PROTAC CDK9 degrader-6
CAS :PROTAC CDK9 degrader-6 targets and degrades CDK9 isoforms via proteasome, with DC50 of 0.10μM and 0.14μM.Formule :C42H49Cl2N9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :878.8THZ1-R
CAS :THZ1-R displays diminished activity for CDK7 inhibition(Kd:142 nM).Formule :C31H30ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.07CLK1-IN-1
CAS :CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).Formule :C24H16FN5OCouleur et forme :SolidMasse moléculaire :409.42Teclistamab
CAS :Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Degré de pureté :95%Couleur et forme :LiquidCDK-TCIP2
DK-TCIP2 is an anticancer agent formed by linking the CDK9 inhibitor SNS-032 and the BCL6 inhibitor BI-3812. This compound exhibits anticancer activity both in vivo and in vitro, making it suitable for research in lymphoma.Formule :C52H67ClN12O8S2Couleur et forme :SolidMasse moléculaire :1087.75SIBA
CAS :SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Formule :C14H21N5O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :339.41Ref: TM-T12908
1mg52,00€5mg94,00€10mg117,00€25mg220,00€50mg329,00€100mg469,00€200mg652,00€1mL*10mM (DMSO)104,00€(R)-Simurosertib
CAS :(R)-Simurosertib ((R)-TAK-931) is an inhibitor of the ATP-competitive cell division cycle 7 (CDC7) kinase.Formule :C17H19N5OSDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :341.43JNJ-7706621
CAS :JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.66%Couleur et forme :SolidMasse moléculaire :394.36Ref: TM-T6126
1mg50,00€2mg66,00€5mg105,00€10mg180,00€25mg284,00€50mg520,00€100mg728,00€500mg1.473,00€1mL*10mM (DMSO)88,00€2'-Deoxy-2'-fluorocytidine
CAS :2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Formule :C9H12FN3O4Degré de pureté :99.03%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :245.21Bleomycin hydrochloride
CAS :Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.Formule :C55H84ClN17O21S3Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :1451.01(Average)Mithramycin A
CAS :Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of variousFormule :C52H76O24Degré de pureté :99.28%Couleur et forme :Yellow PowderMasse moléculaire :1085.15CCT245737
CAS :CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Formule :C16H16F3N7ODegré de pureté :97.06% - 99.69%Couleur et forme :SolidMasse moléculaire :379.34Ref: TM-T7080
1mg39,00€2mg51,00€5mg84,00€10mg119,00€25mg225,00€50mg369,00€100mg552,00€1mL*10mM (DMSO)92,00€DNA gyrase B-IN-3
CAS :DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against GramFormule :C14H9Cl2N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.21IRES-C11
CAS :IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Formule :C13H11Cl2NO4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :316.14Ref: TM-T40419
1mg103,00€5mg246,00€10mg395,00€25mg785,00€50mg1.198,00€100mg1.853,00€200mg2.498,00€1mL*10mM (DMSO)271,00€STF-083010
CAS :STF-083010 is a selective inhibitor of the IRE1α endonuclease.Formule :C15H11NO3S2Degré de pureté :97.53% - 98.85%Couleur et forme :SolidMasse moléculaire :317.38Ref: TM-T6681
5mg51,00€10mg80,00€25mg120,00€50mg205,00€100mg368,00€200mg555,00€500mg810,00€1mL*10mM (DMSO)58,00€ARB-272572
CAS :ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.Formule :C32H36N6O4Degré de pureté :97.36% - 98.07%Couleur et forme :SolidMasse moléculaire :568.675-Bromo-2',3',5'-tri-O-acetyluridine
CAS :5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.21(E/Z)-THZ1 2HCl
CAS :THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.Formule :C31H30Cl3N7O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :638.98TASIN-1
CAS :TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).Formule :C18H28N2O3SDegré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :352.49Ref: TM-T22632
1mg39,00€5mg84,00€10mg131,00€25mg269,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)92,00€GSK2850163
CAS :GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).Formule :C24H29Cl2N3ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :446.41Phthalazinone pyrazole
CAS :Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formule :C18H15N5ODegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T21981
1mg64,00€2mg96,00€5mg145,00€10mg212,00€25mg353,00€50mg532,00€100mg792,00€200mg1.064,00€EHT 1864 2HCl
CAS :EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formule :C25H29Cl2F3N2O4SDegré de pureté :98.39% - 99.42%Couleur et forme :SolidMasse moléculaire :581.47Ref: TM-T6483
1mg47,00€5mg92,00€10mg136,00€25mg259,00€50mg472,00€100mg677,00€200mg934,00€1mL*10mM (DMSO)107,00€(D)-PPA 1 TFA
(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an affinity for PD-1 of 0.51 μM and demonstratingFormule :C72H99F3N20O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1669.67H1k
H1k is an eudistomin Y fluorescent derivative and lysosome-targeted antiproliferative agent that downregulates the expression of cell cycle protein B1.Formule :C27H22N2ODegré de pureté :98.38%Couleur et forme :SoildMasse moléculaire :390.48Nocarnickelamides B
Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.Formule :C29H42N6O9Couleur et forme :SolidMasse moléculaire :618.68LXW7
CAS :LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formule :C29H48N12O12S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :820.89HALOFUGINONE LACTATE
CAS :HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Formule :C19H23BrClN3O6Degré de pureté :99.02% - 99.96%Couleur et forme :SolidMasse moléculaire :504.8Ref: TM-T8785
2mg42,00€5mg59,00€10mg94,00€25mg130,00€50mg207,00€100mg309,00€200mg462,00€1mL*10mM (DMSO)66,00€Amsilarotene
CAS :Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.Formule :C20H27NO3Si2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :385.6Ref: TM-T21314
1mg43,00€2mg57,00€5mg96,00€10mg140,00€25mg273,00€50mg393,00€100mg560,00€200mg757,00€1mL*10mM (DMSO)96,00€ARRY 520 hydrochloride
CAS :'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'Formule :C20H23ClF2N4O2SDegré de pureté :98.06% - 99.26%Couleur et forme :SolidMasse moléculaire :456.94Ref: TM-TQ0318L
1mg59,00€5mg116,00€10mg170,00€25mg304,00€50mg437,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)149,00€L 888607 Racemate
CAS :L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formule :C19H15ClFNO2SCouleur et forme :SolidMasse moléculaire :375.84Arginine-glycine-aspartic acid
CAS :RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formule :C12H22N6O6Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.34Valategrast hydrochloride
CAS :Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41Ascamycin
CAS :Ascamycin: a Streptomyces-made antibiotic targeting Xanthomonas spp. MIC: 0.4-12.5 μg/mL for X. citri, oryzae, and phage.Formule :C13H18ClN7O7SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :451.84Ref: TM-T14329
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)747,00€(E/Z)-ZINC09659342
CAS :(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Formule :C23H15F3N2O4Degré de pureté :95.83%Couleur et forme :SolidMasse moléculaire :440.37Ref: TM-T9986
1mg66,00€5mg145,00€10mg221,00€25mg378,00€50mg533,00€100mg718,00€200mg938,00€1mL*10mM (DMSO)160,00€Irigenin
CAS :Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.315-BrdU
CAS :5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.Formule :C9H11BrN2O5Degré de pureté :99.54% - 99.87%Couleur et forme :Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :307.1Bersanlimab
CAS :Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.22 kDa5-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.79%Couleur et forme :Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :244.2(R)-Atuveciclib
CAS :Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].Formule :C18H18FN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.43αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67VER-00158411
CAS :VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).Formule :C31H34N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.64NSC 617145
CAS :NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormule :C13H10Cl4N2O4Degré de pureté :98.31% - 99.72%Couleur et forme :SolidMasse moléculaire :400.04Ref: TM-T9168
1mg37,00€2mg52,00€5mg77,00€10mg96,00€25mg167,00€50mg240,00€100mg378,00€500mg889,00€1mL*10mM (DMSO)85,00€WRN inhibitor 15
WRN inhibitor 15 (Compound 9) is a WRN inhibitor with antitumor properties, displaying IC50 values of 37.9, 40.2, and 46.6 μM in PC3, LNCaP, and HeLa cells, respectively, making it suitable for prostate cancer research.Formule :C16H13F2N3OCouleur et forme :SolidMasse moléculaire :301.29αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Formule :C25H32F2N4O3Couleur et forme :SolidMasse moléculaire :474.543'-Deoxy-3'-fluoroadenosine
CAS :3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFormule :C10H12FN5O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :269.23Synucleozid hydrochloride
CAS :Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Formule :C22H21ClN6Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :404.9CNDAC hydrochloride
CAS :CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.Formule :C10H13ClN4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :288.69Ref: TM-T13621
1mg114,00€5mg274,00€10mg425,00€25mg702,00€50mg938,00€100mg1.311,00€1mL*10mM (DMSO)250,00€K858 (Racemic)
CAS :K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formule :C13H15N3O2SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :277.34RX-3117
CAS :RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.Formule :C10H12FN3O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :257.22Ref: TM-T16813
1mg157,00€2mg212,00€5mg309,00€10mg444,00€25mg728,00€50mg1.017,00€100mg1.378,00€1mL*10mM (DMSO)319,00€CDK7-IN-25
CAS :CDK7-IN-25 (CY-16-1) is a potent CDK7 inhibitor with an IC50 value of less than 1nM, utilized in cancer research [1].Formule :C33H32N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :560.65Betamethasone 17-benzoate
CAS :Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Formule :C29H33FO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :496.57CDK4-IN-2
CAS :CDK4-IN-2 (A17) is a potent inhibitor of CDK4, exhibiting K i and IC 50 values of less than 10 nM and is utilized in cancer research [1].Formule :C22H26F2N6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.54CDK2-IN-20
CDK2-IN-20 (compound 3b), a CDK2 inhibitor, exhibits cytotoxic effects on tumor cells with an IC50 ranging from 5.52-17.09 µM.Degré de pureté :98%Couleur et forme :Odour SolidCDK4/9-IN-1
CAS :CDK4/9-IN-1 (Compound 29) is a selective dual inhibitor of CDK4 and CDK9, exhibiting IC50 values of 23 nM and 12 nM, respectively. It holds potential for use in cancer research.Formule :C22H34N6O2Couleur et forme :SolidMasse moléculaire :414.544Spartalizumab
CAS :"Spartalizumab (PDR001), a humanized IgG4 monoclonal antibody, targets PD-1 to inhibit PD-L1/L2 interactions, useful in ATC research."Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:96.3%Couleur et forme :LiquidMasse moléculaire :145.74 kDaPurvalanol B
CAS :Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formule :C20H25ClN6O3Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :432.9Ref: TM-T7167
1mg38,00€5mg73,00€10mg95,00€25mg148,00€50mg215,00€100mg323,00€200mg487,00€1mL*10mM (DMSO)81,00€Visugromab
CAS :Visugromab, a GDF-15 neutralizing IgG4 monoclonal antibody (mAb), demonstrates potent efficacy in treating PD-1/PD-L1 relapsed/refractory metastatic solidDegré de pureté :98%Couleur et forme :LiquidN6-(p-Methoxybenzyl)adenosine
CAS :Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.39L-Methioninamide hydrochloride
CAS :L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.Formule :C5H13ClN2OSDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :184.692'-O-(2-Methoxyethyl)adenosine
CAS :2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.32Uridine triphosphate 13C9,15N2 sodium
CAS :Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04BI-1347
CAS :BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formule :C22H20N4ODegré de pureté :96.7% - 99.43%Couleur et forme :SolidMasse moléculaire :356.42Ref: TM-T5405
1mg40,00€5mg88,00€10mg126,00€25mg240,00€50mg439,00€100mg647,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Nofazinlimab
CAS :Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody for the study of unresectable hepatocellular carcinoma (uHCC).Couleur et forme :LiquidCDK9-IN-8
CAS :CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).Formule :C31H32FN7O3Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :569.63RI-1
CAS :RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formule :C14H11Cl3N2O3Degré de pureté :99.3% - 99.62%Couleur et forme :SolidMasse moléculaire :361.61Ganciclovir sodium
CAS :Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formule :C9H13N5NaO4Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :278.226-Hydroxy-DOPA
CAS :6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.Formule :C9H11NO5Degré de pureté :96.59% - 97.23%Couleur et forme :SolidMasse moléculaire :213.19Adavosertib
CAS :Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formule :C27H32N8O2Degré de pureté :100% - 99.82%Couleur et forme :SolidMasse moléculaire :500.6Ref: TM-T2077
5mg48,00€10mg70,00€25mg86,00€50mg92,00€100mg116,00€200mg170,00€500mg274,00€1mL*10mM (DMSO)52,00€Camrelizumab
CAS :Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of upDegré de pureté :98.6%Couleur et forme :LiquidMasse moléculaire :143.7 kDaGSK2850163 (S enantiomer)
CAS :GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a).Formule :C24H29Cl2N3ODegré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :446.41Cyclo(RADfK)
CAS :Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formule :C28H43N9O7Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :617.7LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.Formule :C23H29ClN8ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :469.02Ref: TM-T4417
1mg59,00€2mg85,00€5mg97,00€10mg172,00€25mg339,00€50mg502,00€100mg728,00€1mL*10mM (DMSO)97,00€GRGDSPK
CAS :GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.Formule :C28H49N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.76ZNL-05-044
ZNL-05-044, a CDK11 inhibitor, exhibits IC50 values of 0.23 μM for CDK11A and 0.27 μM for CDK11B, as determined by NanoBRET assay.Formule :C21H22Cl2N6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.41MDEG-541
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].Formule :C35H38N4O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.76TAK-960
CAS :TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Formule :C27H34F3N7O3Degré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :561.6Ref: TM-T7200
1mg64,00€2mg89,00€5mg120,00€10mg170,00€25mg294,00€50mg490,00€100mg710,00€1mL*10mM (DMSO)170,00€BRD32048
CAS :BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.Formule :C16H22N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :314.39Ref: TM-T23820
2mg52,00€5mg111,00€10mg175,00€25mg321,00€50mg512,00€100mg825,00€200mg1.111,00€1mL*10mM (DMSO)47,00€UNC9512
UNC9512 is a potent antagonist of the methyl-lysine reader protein 53BP1, which can be utilized to investigate the function of 53BP1 in DNA repair, gene editingFormule :C31H34N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.64(E/Z)-Rigosertib sodium
CAS :ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay).Formule :C21H24NNaO8SDegré de pureté :97.16% - 99.82%Couleur et forme :SolidMasse moléculaire :473.47CCT129202
CAS :CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively.Formule :C23H25ClN8OSDegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :497.02Elarofiban
CAS :Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formule :C22H32N4O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :416.51p21PBP
p21PBP, a peptide composed of 20 amino acids, serves as an inhibitor of DNA replication. It specifically binds to the purified proliferating cell nuclear antigen (PCNA) found in extracts from tumor cells. p21PBP holds potential for use in cancer research.Formule :C112H181N37O30SCouleur et forme :SolidMasse moléculaire :2557.93Cdk2 Inhibitor II
CAS :Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formule :C14H11BrN4O3SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :395.23Ref: TM-T36933
1mg103,00€2mg140,00€5mg202,00€10mg305,00€25mg512,00€50mg730,00€100mg998,00€500mg1.977,00€IXA4
CAS :IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.Formule :C24H28N4O4Degré de pureté :97.59% - 98.69%Couleur et forme :SolidMasse moléculaire :436.5YK-2168
CAS :YK-2168 is a differentiated selective inhibitor of CDK9.Formule :C16H18ClN5Couleur et forme :SolidMasse moléculaire :315.80PF07104091
CAS :PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation. Cost-effective and quality-assured.Formule :C19H28N6O4Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :404.46Ref: TM-T9712
1mg354,00€2mg518,00€5mg823,00€10mg1.206,00€25mg1.795,00€50mg2.422,00€100mg3.258,00€1mL*10mM (DMSO)914,00€2'-Fluoro-2'-Deoxyadenosine
CAS :2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formule :C10H12FN5O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :269.23BMS-265246
CAS :BMS-265246 is a potent and selective CDK1/2 inhibitor.Formule :C18H17F2N3O2Degré de pureté :98.77% - 99.55%Couleur et forme :SolidMasse moléculaire :345.34Ref: TM-T2679
1mg35,00€5mg74,00€10mg116,00€25mg221,00€50mg335,00€100mg480,00€200mg652,00€1mL*10mM (DMSO)82,00€2'-Deoxy-5,6-dihydrouridine
CAS :2'-Deoxy-5,6-dihydrouridine is a nucleoside analog that contains a dihydro group in its molecular structure,commonly used in base excision related studies.Formule :C9H14N2O5Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :230.229-(β-D-Xylofuranosyl)adenine
CAS :9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormule :C10H13N5O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :267.24PVZB1194
CAS :PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFormule :C13H9F4NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.28(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).Formule :C24H25Cl2F3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.38(±)-Enitociclib
CAS :(±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is highly selective inhibitor of PTEF/CDK9.Formule :C19H18F2N4O2SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :404.43Ref: TM-T13467
1mg37,00€5mg88,00€10mg120,00€25mg216,00€50mg354,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)87,00€CDK9 inhibitor HH1
CAS :CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.Formule :C13H15N3OSDegré de pureté :97.97%Couleur et forme :SolidMasse moléculaire :261.34RP-6306
CAS :Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.Formule :C18H20N4O2Degré de pureté :98.41% - 99.28%Couleur et forme :SolidMasse moléculaire :324.38CDK2 degrader 3
CAS :CDK2 degrader3 selectively degrades CDK2 and exhibits antitumor activity.Formule :C44H53ClN10O6SCouleur et forme :SolidMasse moléculaire :885.47Lerociclib
CAS :Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.Formule :C26H34N8ODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :474.6360A
CAS :360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).Formule :C27H23N5O2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.5Apcin
CAS :Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.Formule :C13H14Cl3N7O4Degré de pureté :96.74%Couleur et forme :SolidMasse moléculaire :438.65Ref: TM-T8561
1mg48,00€2mg63,00€5mg87,00€10mg140,00€25mg274,00€50mg472,00€100mg710,00€1mL*10mM (DMSO)97,00€Rosnilimab
CAS :Rosnilimab is a humanized IgG1-κ antibody that targets PD-1 [1] [2].Degré de pureté :98%Couleur et forme :LiquidEHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :100% - 99.86%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg48,00€10mg73,00€25mg127,00€50mg213,00€100mg334,00€200mg492,00€500mg787,00€1mL*10mM (DMSO)52,00€YJ1206
CAS :YJ1206 is a highly potent and selective CDK12/13 PROTAC degrader oral, DNA damage and cell-cycle arrest,and inhibits the proliferation of prostate cancer cells.Formule :C49H52FN11O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :894.01MBM-17S
CAS :MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormule :C36H40N6O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :716.74WRN inhibitor 2
CAS :WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].Formule :C15H11F3N2O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38DMT-dG(ib) Phosphoramidite
CAS :DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formule :C44H54N7O8PDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :839.92SU-9516
CAS :SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.Formule :C13H11N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T8819
1mg90,00€5mg131,00€10mg170,00€25mg248,00€50mg321,00€100mg419,00€500mg938,00€1mL*10mM (DMSO)117,00€Aaptamine
CAS :Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.Formule :C13H12N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :228.25c-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in ratFormule :C20H22N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.43AI-10-49
CAS :AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formule :C30H22F6N6O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :660.52Ref: TM-T6753
2mg40,00€5mg60,00€10mg96,00€25mg169,00€50mg245,00€100mg361,00€200mg512,00€1mL*10mM (DMSO)88,00€SR15006
CAS :SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Formule :C16H20ClN3O4SDegré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :385.87Ref: TM-T60037
5mg39,00€10mg64,00€25mg117,00€50mg212,00€100mg316,00€200mg454,00€1mL*10mM (DMSO)62,00€SB-743921 hydrochloride
CAS :SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formule :C31H34Cl2N2O3Degré de pureté :95.58% - 99.70%Couleur et forme :SolidMasse moléculaire :553.52Ref: TM-T2255
1mg42,00€5mg106,00€10mg163,00€25mg278,00€50mg429,00€100mg657,00€500mg1.501,00€1mL*10mM (DMSO)130,00€13-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23DL-Alanosine
CAS :DL-Alanosine is an amino acid analog with antitumor activity.Formule :C3H7N3O4Couleur et forme :SolidMasse moléculaire :149.105Caracemide
CAS :Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formule :C6H11N3O4Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :189.17AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.Formule :C28H32FN9O2Couleur et forme :SolidMasse moléculaire :545.61PD-1-IN-17
CAS :PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.Formule :C13H22N6O7Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :374.35PD-L1-IN-2
CAS :PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.Formule :C33H38N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.68Laromustine
CAS :Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Formule :C6H14ClN3O5S2Couleur et forme :SolidMasse moléculaire :307.785-Fluorouridine 5'-phosphate
CAS :5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.Formule :C9H12FN2O9PCouleur et forme :SolidMasse moléculaire :342.172AS2863619 free base
CAS :AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.Formule :C16H12N8OCouleur et forme :SolidMasse moléculaire :332.32KB-0742 dihydrochloride
CAS :KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.Formule :C16H27Cl2N5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :360.33Ref: TM-T9446
1mg96,00€2mg143,00€5mg235,00€10mg378,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)249,00€2-Keto-D-galactose
CAS :2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formule :C6H10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :178.14Zn(BQTC)
CAS :Zn(BQTC) inhibits mtDNA and nDNA, damages mitochondria/nuclei, triggers apoptosis, and targets A549R cancer cells.Formule :C30H36Cl2N5O3ZnDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :650.92Ocifisertib(CFI-400945 free base)
CAS :Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.Formule :C33H34N4O3Degré de pureté :97.56% - 98.53%Couleur et forme :SolidMasse moléculaire :534.65ATN-161 trifluoroacetate salt
CAS :ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Eciruciclib
CAS :Eciruciclib is an inhibitor of CDK with antitumor properties.Formule :C27H33FN8Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :488.6IBR2
CAS :IBR2 is a potent RAD51 inhibitor that disrupts DNA repair, inhibits cancer cell growth, and induces apoptosis.Formule :C24H20N2O2SDegré de pureté :96.15%Couleur et forme :SolidMasse moléculaire :400.49Ref: TM-T11600
1mg35,00€5mg70,00€10mg111,00€25mg183,00€50mg259,00€100mg359,00€200mg532,00€1mL*10mM (DMSO)77,00€Tirofiban
CAS :Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formule :C22H36N2O5SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :440.6Enoxacin
CAS :Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formule :C15H17FN4O3Degré de pureté :98.68% - 99.89%Couleur et forme :Off-White To Yellow CrystalsMasse moléculaire :320.32