Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase
- CDK
- Arrêt du cycle cellulaire
- Chk
- c-Myc
- Dynamine
- DYRK
- Ferroptose
- HSP
- Intégrine
- Kinésine
- KSP
- LIM Kinase
- Microtubules associés
- PKC
- PLK
- Rho
- ROCK
- Wee1
Affichez 11 plus de sous-catégories
Produits appartenant à la catégorie "Cycle cellulaire/point de contrôle"
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Anti-Mouse PD-1 Antibody (RMP1-14)
RMP1-14 is an IgG1-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.Degré de pureté :14.68mg/ml - >95%Couleur et forme :Odour LiquidTREX1-IN-3
CAS :TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898Lipustobart
CAS :Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplasticDegré de pureté :98%Couleur et forme :Liquid2',3'-Isopropylideneuridine
CAS :2',3'-Isopropylideneuridine is a nucleoside derivative that has shown antiviral activity in several studies, particularly against Flaviviruses, such as HCV.Formule :C12H16N2O6Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :284.27N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
CAS :N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity.Formule :C47H52N7O7PDegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :857.93Ref: TM-TNU1119
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€500mg3.734,00€DMT-2′Fluoro-dU Phosphoramidite
CAS :DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Formule :C39H46FN4O8PDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :748.78Azelaoyl PAF
CAS :Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Formule :C33H66NO9PCouleur et forme :SolidMasse moléculaire :651.85Polθ-IN-5
CAS :Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.Formule :C23H18ClF2N7O3SCouleur et forme :SolidMasse moléculaire :545.95CYC-116
CAS :CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormule :C18H20N6OSDegré de pureté :96.6% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46Ref: TM-T6458
2mg39,00€5mg56,00€10mg78,00€25mg135,00€50mg217,00€100mg358,00€500mg908,00€1mL*10mM (DMSO)49,00€BAY1217389
CAS :BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formule :C27H24F5N5O3Degré de pureté :95.71% - 98.78%Couleur et forme :SolidMasse moléculaire :561.5Paprotrain
CAS :Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formule :C16H11N3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :245.28Ref: TM-T12359
5mg48,00€10mg62,00€25mg97,00€50mg169,00€100mg250,00€200mg373,00€500mg612,00€1mL*10mM (DMSO)52,00€CDK4/6-IN-2
CAS :CDK4/6-IN-2 是一种CDK4和CDK6抑制剂,IC50分别为 2.7 和 16 nM。Formule :C27H32F2N8Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :506.59Cytidine
CAS :Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond.Formule :C9H13N3O5Degré de pureté :98.80% - 99.63%Couleur et forme :Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :243.22T2AA
CAS :T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-Formule :C15H15I2NO3Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :511.09QR-6401
CAS :QR-6401, a selective macrocyclic CDK2 inhibitor, is orally active with IC50 values of 0.37 nM for CDK2/E1, 10 nM for CDK9/T1, 22 nM for CDK1/A2, 34 nM for CDK6/Formule :C19H23N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.42N,N-Dimethyl-2'-O-methylcytidine
CAS :N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.Formule :C12H19N3O5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :285.32'-O-Methyl-5-iodouridine
CAS :2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses aFormule :C10H13IN2O6Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :384.12Deoxycytidine triphosphate
CAS :dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.Formule :C9H16N3O13P3Degré de pureté :95.19%Couleur et forme :SolidMasse moléculaire :467.16Kif15-IN-1
CAS :Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formule :C20H22N4O5SDegré de pureté :99.39% - 99.39%Couleur et forme :SolidMasse moléculaire :430.48TC-Mps1-12
CAS :TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Formule :C17H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38N2-Methylguanosine
CAS :N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA'sFormule :C11H15N5O5Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :297.27PNU112455A hydrochloride
CAS :PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.Formule :C10H12ClN5O2SDegré de pureté :98.58% - 99.22%Couleur et forme :SolidMasse moléculaire :301.75Ref: TM-T8230
2mg47,00€5mg74,00€10mg105,00€25mg182,00€50mg281,00€100mg459,00€500mg1.017,00€1mL*10mM (DMSO)84,00€L82-G17
CAS :L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.Formule :C11H9ClN4O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :264.67αVβ8-IN-1
CAS :αVβ8-IN-1 is an inhibitor of the αVβ8 integrin. It exhibits growth-suppressive activity against tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 is suitable for research related to idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), and various cancers.Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.01Pritelivir
CAS :Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formule :C18H18N4O3S2Degré de pureté :97.96% - 99.42%Couleur et forme :SolidMasse moléculaire :402.49Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidTipiracil hydrochloride
CAS :Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Formule :C9H12Cl2N4O2Degré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :279.12Bimosiamose
CAS :Bimosiamose has anti-inflammatory effects[1].Formule :C46H54O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :862.91αvβ1 integrin-IN-1
CAS :αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Formule :C26H34N6O6SDegré de pureté :100% - 99.74%Couleur et forme :SolidMasse moléculaire :558.65Ref: TM-T13473
1mg115,00€5mg274,00€10mg432,00€25mg697,00€50mg938,00€100mg1.293,00€200mg1.738,00€1mL*10mM (DMSO)349,00€DHX9-IN-4
CAS :DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.Formule :C21H22ClN5O4S2Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :508.01PDL-1 cpd 10
CAS :PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.Formule :C21H23N5O2Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :377.44Ref: TM-T9359
1mg55,00€5mg117,00€10mg187,00€25mg393,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)134,00€K34c hydrochloride
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Formule :C38H50ClN5O2Degré de pureté :100% - 99.95%Couleur et forme :SoildMasse moléculaire :644.29Ref: TM-T41151L
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)887,00€LP23
LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration of immune cell function in HepG2/JurkatFormule :C27H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.59SCH900776
CAS :SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.Formule :C15H18BrN7Degré de pureté :96.69% - 99.6%Couleur et forme :SolidMasse moléculaire :376.25Ref: TM-T2517
1mg52,00€2mg78,00€5mg115,00€10mg168,00€25mg283,00€50mg462,00€100mg660,00€1mL*10mM (DMSO)124,00€Lifitegrast sodium
CAS :Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Formule :C29H23Cl2N2NaO7SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :637.46Pembrolizumab
CAS :Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.Degré de pureté :95% - 99.70%Couleur et forme :LiquidMasse moléculaire :149 kDaART812
CAS :ART812 is an orally active inhibitor of DNA polymerase Polθ, possessing an IC50 value of 7.6 nM.Formule :C19H16ClF4N3O4Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :461.79Ref: TM-T40236
1mg116,00€5mg283,00€10mg452,00€25mg747,00€50mg1.103,00€100mg1.539,00€1mL*10mM (DMSO)280,00€XU1
CAS :XU1(Benzo[c][1,8]naphthyridin-6(5h)-One) is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation orFormule :C12H8N2ODegré de pureté :100% - 98.97%Couleur et forme :SolidMasse moléculaire :196.2Atuveciclib
CAS :Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Formule :C18H18FN5O2SDegré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :387.43Ref: TM-T10464L
1mg88,00€2mg120,00€5mg202,00€10mg329,00€25mg612,00€50mg817,00€100mg1.121,00€1mL*10mM (DMSO)224,00€CDK7-IN-22
CAS :CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].Formule :C22H25F3N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.47CID44216842
CAS :CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formule :C22H20BrN3O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.38Ref: TM-T8930
2mg35,00€5mg52,00€10mg89,00€25mg167,00€50mg258,00€100mg379,00€200mg540,00€1mL*10mM (DMSO)58,00€Cidofovir
CAS :Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。Formule :C8H14N3O6PDegré de pureté :99.24% - 99.76%Couleur et forme :Fluffy White PowderMasse moléculaire :279.19Dyrk1A-IN-12
CAS :Dyrk1A-IN-12 (compound S43) is an inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1A). It has an IC50 of 95 nM for inhibiting Dyrk1A. The compound demonstrates antiviral activity against EV-A71 (Enterovirus A71) with an EC50 of 4.4 μM, a CC50 of 12.8 μM, and a selectivity index (SI) of 2.9. Additionally, Dyrk1A-IN-12 exhibits potent inhibitory effects on the herpes simplex virus (HSV).Formule :C22H16FN3O2SCouleur et forme :SolidMasse moléculaire :405.445Cytarabine hydrochloride
CAS :Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase.Formule :C9H14ClN3O5Degré de pureté :99.62%Couleur et forme :White PowderMasse moléculaire :279.68Dihydro-5-azacytidine acetate
CAS :Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1Formule :C10H18N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.27N6-Methyl-2'-O-methyladenosine
CAS :N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFormule :C12H17N5O4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :295.29Trovafloxacin mesylate
CAS :Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formule :C21H19F3N4O6SDegré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :512.46ML327
CAS :ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formule :C19H18N4O4Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :366.37Ap4dT
CAS :Ap4dT serves as an inhibitor of human adenylate kinase isozyme 1 (hAK1), effectively suppressing the synthesis of ATP and ADP, with IC50 values of 42 μM and 38 μM, respectively.Formule :C20H41N11O20P4Couleur et forme :SolidMasse moléculaire :879.5α7β1 integrin modulator-1
CAS :α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].Formule :C23H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.562'-Deoxyadenosine-5'-triphosphate trisodium
CAS :2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNAFormule :C10H13N5Na3O12P3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :557.13dUTP trisodium
CAS :dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.Formule :C9H12N2Na3O14P3Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :534.09Abituzumab
CAS :Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Degré de pureté :>95%Couleur et forme :Liquid5-Hydroxyuridine
CAS :5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.Formule :C9H12N2O7Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :260.2Votoplam
CAS :Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].Formule :C21H25N9ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.48Eciskafusp alfa
CAS :Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specificDegré de pureté :98%Couleur et forme :SolidAPE1-IN-3
CAS :APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.Formule :C17H16O4Couleur et forme :SolidMasse moléculaire :284.31Dehydroaltenusin
CAS :Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM).Formule :C15H12O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.255Anti-Mouse PD-L1 Antibody (10F.9G2)
Anti-Mouse PD-L1 Antibody (10F.9G2) is an IgG-class antibody against mouse PD-L1.Degré de pureté :98.92% - >95% Determined by SDS-PAGECouleur et forme :Odour LiquidEgaptivon pegol
CAS :Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thromboticDegré de pureté :98%Couleur et forme :Liquid2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc
2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker polymer of AUTACPD-L1degrader-3. It can be utilized in the synthesis of AUTAC.Formule :C35H45N5O6Couleur et forme :SolidMasse moléculaire :631.76Clofarabine-5'-triphosphate
CAS :Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.Formule :C10H14ClFN5O12P3Couleur et forme :SolidMasse moléculaire :543.62PD-1/PD-L1-IN-10
CAS :PD-1/PD-L1-IN-10 is an orally available PD-1/PD-L1 inhibitor (IC50 value of 2.7 nM) that shows anti-tumor activity.Cost-effective and quality-assured.Formule :C33H31N3O7Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :581.62CDK9-IN-26
CDK9-IN-26, also known as compound 1, is a potent inhibitor of Cyclin-Dependent Kinase 9 (CDK9) with an IC50 value of 0.18 μM.[1]Formule :C17H14N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.32Leukadherin-1
CAS :Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formule :C22H15NO4S2Degré de pureté :98% - 98.49%Couleur et forme :SolidMasse moléculaire :421.49Palbociclib orotate
CAS :Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively.Formule :C29H33N9O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.63Acelarin
CAS :Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.Formule :C25H27F2N4O8PDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :580.47Ref: TM-T4060
1mg46,00€2mg59,00€5mg87,00€10mg144,00€25mg274,00€50mg487,00€100mg708,00€1mL*10mM (DMSO)97,00€CM03
CAS :CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.Formule :C34H44N6O6Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :632.75S-trityl-L-Cysteine
CAS :S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formule :C22H21NO2SDegré de pureté :97.02%Couleur et forme :Almost White To Light Yellow Granular PowderMasse moléculaire :363.476-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS :6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).Formule :C8H7BrO3Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :231.04TH287
CAS :TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Formule :C11H10Cl2N4Degré de pureté :97.73% - 99%Couleur et forme :SolidMasse moléculaire :269.13Ref: TM-T2069
1mg37,00€2mg48,00€5mg72,00€10mg96,00€25mg188,00€50mg366,00€100mg545,00€1mL*10mM (DMSO)79,00€Litronesib
CAS :Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.Formule :C23H37N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.7Polθ-IN-6
CAS :Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.Formule :C25H23N3O3SCouleur et forme :SolidMasse moléculaire :445.53Aurora inhibitor 1
CAS :Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).Formule :C23H25N9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.57WRN inhibitor 17
CAS :WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.Formule :C33H34F4N4O6SCouleur et forme :SolidMasse moléculaire :690.71Palbociclib Isethionate
CAS :Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂,IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。Formule :C24H29N7O2·C2H6O4SDegré de pureté :99.01% - 99.27%Couleur et forme :SolidMasse moléculaire :573.66Mps1-IN-3
CAS :Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formule :C26H31N7O4SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :537.63Ref: TM-T16130
2mg42,00€5mg64,00€10mg92,00€25mg170,00€50mg311,00€100mg449,00€200mg630,00€1mL*10mM (DMSO)74,00€Danofloxacin
CAS :Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Formule :C19H20FN3O3Degré de pureté :99.77% - 99.80%Couleur et forme :SolidMasse moléculaire :357.38Moloney murine leukemia virus RT
Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to the retrovirus life cycle [1].Degré de pureté :98%Couleur et forme :Odour SolidIMP-1088
CAS :IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Formule :C25H29F2N5ODegré de pureté :98.26% - 99.08%Couleur et forme :SolidMasse moléculaire :453.53Ref: TM-T9350
1mg144,00€2mg188,00€5mg283,00€10mg469,00€25mg833,00€50mg1.121,00€1mL*10mM (DMSO)310,00€DNA Gyrase-IN-16
CAS :DNA Gyrase-IN-16 (Compound 9) is an inhibitor of DNA gyrase, with an IC50 of 1.609 μM. It exhibits antibacterial properties, effectively inhibiting S. aureus and MRSA, with a MIC of 3.125 μM for both.Formule :C17H15N3O3Couleur et forme :SolidMasse moléculaire :309.319LSN2839567
CAS :LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Formule :C25H28F2N8Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :478.54Palbociclib hydrochloride
CAS :Palbociclib hydrochloride is the salt form of Palbociclib, a selective and orally available CDK4 and CDK6 inhibitor for breast and hepatocellular carcinoma.Formule :C24H31Cl2N7O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :520.46BOS-172722
CAS :BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formule :C24H30N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :446.556-Thio-2'-Deoxyguanosine
CAS :6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formule :C10H13N5O3SDegré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :283.31Calcium N5-methyltetrahydrofolate
CAS :Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease andFormule :C20H23CaN7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.51Folinic acid calcium
CAS :Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.Formule :C20H21CaN7O7Degré de pureté :100% - 99.5%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :511.51Opugotamig
Opugotamig is a chimeric antibody of the half-IG G1 -κ/(scFv -κ-heavy) -h-CH2-CH3 type, specifically targeting FOLR1.Couleur et forme :Odour LiquidML-099
CAS :ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Formule :C14H13NO2SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :259.32Ref: TM-T22991
1mg48,00€2mg64,00€5mg96,00€10mg153,00€25mg305,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)94,00€15(S)-HpETE
CAS :15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47LNA-Adenosine
CAS :LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.Formule :C11H13N5O4Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :279.25Famciclovir
CAS :Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Formule :C14H19N5O4Degré de pureté :99.85%Couleur et forme :Off-White PowderMasse moléculaire :321.33SMN-C3
CAS :SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).Formule :C24H28N6ODegré de pureté :98.21% - 99.31%Couleur et forme :SolidMasse moléculaire :416.52Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 98.03%Couleur et forme :SolidMasse moléculaire :488.54DNA Gyrase-IN-12
DNA Gyrase-IN-12 (Compound 6d) is an inhibitor of DNA gyrase. It exhibits antibacterial activity with MIC values ranging from 0.031 to 0.0625 μg/mL against Vancomycin-Intermediate Staphylococcus aureus (VISA) and Enterococcus faecium.Couleur et forme :Odour SolidKIF18A-IN-16
CAS :KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Formule :C30H37N5O4SCouleur et forme :SolidMasse moléculaire :563.71DHX9-IN-6
CAS :DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.Formule :C23H18ClFN4O4S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :533Dencatistat
CAS :Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.Formule :C24H27N7O5SDegré de pureté :98.85%Couleur et forme :SolidMasse moléculaire :525.584-Oxofenretinide
CAS :4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.Formule :C26H31NO3Degré de pureté :96.89%Couleur et forme :SolidMasse moléculaire :405.53Ref: TM-T4189
1mg44,00€2mg55,00€5mg79,00€10mg113,00€25mg195,00€50mg293,00€100mg528,00€1mL*10mM (DMSO)96,00€Tacaciclib
CAS :Tacaciclib is a cyclin-dependent kinase (CDK) inhibitor with observed antineoplastic activity [1].Formule :C30H36N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.65HNC-1664
CAS :HNC-1664 is an orally active inhibitor of RNA-dependent RNA polymerase (RdRP). It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 wild type and its variants (XBB.1.18, HK.3.1, BF.7.14, BA.1, HCoV-229E, HCoV-OC43), as well as arenaviruses. HNC-1664 also demonstrates anti-infective efficacy in a mouse model infected with the SARS-CoV-2 Delta variant.Formule :C12H13FIN3O3Couleur et forme :SolidMasse moléculaire :393.153AZD-7762
CAS :AZD-7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Formule :C17H19FN4O2SDegré de pureté :98.96% - 99.19%Couleur et forme :SolidMasse moléculaire :362.42Ref: TM-T6093
1mg38,00€2mg49,00€5mg81,00€10mg96,00€25mg177,00€50mg280,00€100mg449,00€1mL*10mM (DMSO)88,00€WBC100
CAS :WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathwayFormule :C25H33NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.53SB-218078
CAS :SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).Formule :C24H15N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.39Lusianthridin
CAS :Lusianthridin is a natural product from Dendrobium venustum.Formule :C15H14O3Degré de pureté :99.11% - 99.11%Couleur et forme :SolidMasse moléculaire :242.27ddTTP trisodium
Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNAFormule :C10H14N2Na3O13P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.11Danofloxacin mesylate
CAS :Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.Formule :C19H20FN3O3·CH4O3SDegré de pureté :99.73%Couleur et forme :Crystalline SolidMasse moléculaire :453.48SMN-C2
CAS :SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Formule :C24H27N5O2Degré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :417.5NSC 23766
CAS :NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Formule :C24H35N7Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :421.58Gentisin
CAS :Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.Formule :C14H10O5Degré de pureté :95.34%Couleur et forme :SolidMasse moléculaire :258.23GFB-12811
CAS :GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.Formule :C22H23F4N5ODegré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :449.44L-Uridine
CAS :L-Uridine, an RNA component from Poria cocos fungus, is a D-uridine enantiomer with antiviral potential and a phosphate acceptor.Formule :C9H12N2O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :244.2LFM-A13
CAS :LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR,Formule :C11H8Br2N2O2Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :360qsl-304
QSL-304 is a DNA gyrase B inhibitor that serves as an antibacterial agent, exhibiting an IC50 of 31.23 mg/mL against Staphylococcus aureus SA-P2003 [1].Formule :C11H9NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :283.32Tetrapeptide
CAS :Tetrapeptide, an α-MSH analogue, stimulates melanin production and mitigates DNA damage by attenuating reactive oxidative species generation and augmenting DNAFormule :C32H40N10O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :644.72CDK9-IN-10
CAS :CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.Formule :C22H16O5Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :360.36Methotrexate metabolite
CAS :DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.Formule :C15H15N7O2Degré de pureté :95.28% - 99.7%Couleur et forme :SolidMasse moléculaire :325.33XMD-17-51
CAS :XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Formule :C21H24N8ODegré de pureté :99.39%Couleur et forme :SoildMasse moléculaire :404.47Pidilizumab
CAS :Pidilizumab (CT-011), a humanized IgG1κ anti-PD-1 monoclonal antibody, serves as a DLL1 antagonist with potential applications in researching hematologicDegré de pureté :98%Couleur et forme :LiquidLZ9
CAS :LZ9 is an ATP-competitive inhibitor of CDK1 and CDK2, with potential applications in colorectal cancer (CRC) research.Formule :C17H11F3N4O2Couleur et forme :SolidMasse moléculaire :360.29Carmofur
CAS :Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Formule :C11H16FN3O3Degré de pureté :98.59% - 99.48%Couleur et forme :SolidMasse moléculaire :257.265-Ethynyluridine
CAS :5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formule :C11H12N2O6Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :268.22Ref: TM-T36971
5mg51,00€10mg88,00€25mg145,00€50mg250,00€100mg363,00€200mg545,00€1mL*10mM (DMSO)57,00€CDK2/4-IN-2
CAS :CDK2/4-IN-2 (compound 56) serves as a dual inhibitor for CDK2 and CDK4, exhibiting an IC50 of less than 100 nM. It is applicable in cancer research.Formule :C18H20F3N7O3S2Couleur et forme :SolidMasse moléculaire :503.52Abemaciclib
CAS :Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Formule :C27H32F2N8Degré de pureté :99.39% - 99.87%Couleur et forme :SolidMasse moléculaire :506.595-(Methoxycarbonyl)methyluridine
CAS :5-(Methoxycarbonyl)methyluridine is an important modifying nucleotide in tRNAs, and the lack of the mcm5U modification leads to increased protein aggregation.Formule :C12H16N2O8Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :316.26GSK-1520489A
CAS :GSK-1520489A is an active PKMYT1 inhibitor.Formule :C21H23N5O3SDegré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :425.5D5B
D5B is an effective and selective PD-L1 inhibitor that has been modified with DBCO. It degrades PD-L1 in 4T1 and B16-F10 tumor cells with EC50 values of 5.4 μM and 6.2 μM, respectively. D5B can block the PD-L1/PD-1 interaction and exhibits antitumor activity.Formule :C58H66N2O12Couleur et forme :SolidMasse moléculaire :983.15TH287 hydrochloride
CAS :TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.Formule :C11H11Cl3N4Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :305.59ANI-7
CAS :ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).Formule :C13H8Cl2N2Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :263.12CDK4/6-IN-3
CAS :CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.Formule :C25H31FN8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.57Danusertib
CAS :Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formule :C26H30N6O3Degré de pureté :97.88% - 98.44%Couleur et forme :White PowderMasse moléculaire :474.55Ref: TM-T2094
1mg59,00€2mg85,00€5mg116,00€10mg188,00€25mg365,00€50mg555,00€100mg795,00€500mg1.605,00€1mL*10mM (DMSO)120,00€DNA polymerase-IN-2
DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, demonstrates inhibitory activity towards Taq DNA polymerase, with an IC50 value of 48.25 μM, and holdsFormule :C14H12O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.31TAS-119
CAS :TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95Formule :C23H22Cl2FN5O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :506.36Ref: TM-T34787
1mg97,00€5mg235,00€10mg378,00€25mg748,00€50mg1.169,00€100mg1.644,00€1mL*10mM (DMSO)261,00€ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47Ref: TM-T2358
1mg51,00€2mg72,00€5mg105,00€10mg159,00€25mg279,00€50mg462,00€100mg648,00€1mL*10mM (DMSO)116,00€Mefenidil
CAS :Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.Formule :C12H11N3Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :197.24Volociximab
CAS :Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.Degré de pureté :95%Couleur et forme :LiquidPKMYT1-IN-3
PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 nM and exhibiting antitumor activity.Formule :C24H26FN5O2Couleur et forme :SolidMasse moléculaire :435.49MKC3946
CAS :MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.Formule :C21H20N2O3SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :380.46Ref: TM-TQ0101
1mg66,00€5mg170,00€10mg265,00€25mg444,00€50mg653,00€100mg929,00€1mL*10mM (DMSO)157,00€ML216
CAS :ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formule :C15H9F4N5OSDegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :383.323'-Deoxy-3'-fluoroguanosine
CAS :3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons.Formule :C10H12FN5O4Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :285.23CHK1-IN-4
CAS :CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.Formule :C18H18BrN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.29Butylparaben sodium
CAS :Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1Formule :C11H13NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.21MSC2530818
CAS :MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Formule :C18H17ClN4ODegré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :340.81Ref: TM-TQ0266
1mg66,00€5mg144,00€10mg230,00€25mg509,00€50mg735,00€100mg1.026,00€1mL*10mM (DMSO)159,00€Lucanthone
CAS :Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formule :C20H24N2OSDegré de pureté :99.92%Couleur et forme :Yellow Crystals From Alcohol SolidMasse moléculaire :340.48Ref: TM-T4569
1mg56,00€2mg80,00€5mg126,00€10mg188,00€25mg400,00€50mg592,00€100mg837,00€1mL*10mM (DMSO)140,00€BIO-1211
CAS :BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8Mps1-IN-2
CAS :Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formule :C26H36N6O3Degré de pureté :96.24% - 99.75%Couleur et forme :SolidMasse moléculaire :480.6CDK12-IN-5
CAS :CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formule :C18H15F5N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :454.36Ref: TM-T40290
1mg165,00€5mg399,00€10mg645,00€25mg1.320,00€50mg2.080,00€100mg2.822,00€1mL*10mM (DMSO)439,00€Cdc7-IN-5
CAS :Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.Formule :C25H23N3O5Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :445.47Ref: TM-T10727
1mg96,00€5mg227,00€10mg376,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)250,00€COH1
CAS :COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].Formule :C11H10N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :250.27Bexotegrast
CAS :Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formule :C27H36N6O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :492.61Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Couleur et forme :LiquidMasse moléculaire :145.5 kDaHPH-15
CAS :HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.Formule :C19H31N3S4Couleur et forme :SolidMasse moléculaire :429.735-Fluorouridine
CAS :5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.Formule :C9H11FN2O6Degré de pureté :99.53% - 99.76%Couleur et forme :White PowderMasse moléculaire :262.19ML264
CAS :ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Formule :C17H21ClN2O4SDegré de pureté :99.33% - 99.45%Couleur et forme :SolidMasse moléculaire :384.88CDK2-IN-30
CAS :CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.Formule :C18H25N7O3SCouleur et forme :SolidMasse moléculaire :419.502-Fluoroadenine
CAS :2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Formule :C5H4FN5Degré de pureté :99.49%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :153.12BS194
CAS :BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Formule :C20H27N5O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :385.463,4-Dihydroxybenzylamine hydrobromide
CAS :3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formule :C7H10BrNO2Degré de pureté :97.28%Couleur et forme :Light Beige Crystalline PowderMasse moléculaire :220.06BMS-688521
CAS :BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formule :C26H19Cl2N5O4Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :536.37Ref: TM-T14676
1mg183,00€5mg464,00€10mg655,00€25mg1.169,00€50mg1.539,00€100mg1.882,00€1mL*10mM (DMSO)547,00€LY3405105
CAS :LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Formule :C26H39N7O3Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :497.63IMT1
CAS :IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formule :C21H21NO4Degré de pureté :98.07% - 98.14%Couleur et forme :SolidMasse moléculaire :351.4Ref: TM-T8841
1mg81,00€5mg170,00€10mg301,00€25mg563,00€50mg805,00€100mg1.111,00€1mL*10mM (DMSO)188,00€PHI-101
CAS :PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.Formule :C19H19FN4O2SDegré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :386.44Ref: TM-T81490
1mg173,00€5mg437,00€10mg702,00€25mg1.406,00€50mg2.262,00€100mg3.600,00€1mL*10mM (DMSO)469,00€SEL120-34A HCl
CAS :SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormule :C15H19Br2ClN4Degré de pureté :98.13% - 99.75%Couleur et forme :SolidMasse moléculaire :450.6(S)-GNA-T-phosphoramidite
CAS :(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Formule :C38H47N4O7PDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :702.78AZD-5438
CAS :AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Formule :C18H21N5O2SDegré de pureté :99.73% - 99.87%Couleur et forme :SolidMasse moléculaire :371.46BUR1
CAS :BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formule :C16H17N5Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :279.34Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFormule :C184H284N52O57S8·3C2H4O2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :4573.21MYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tetheredFormule :C55H58N10O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1067.17Lerociclib dihydrochloride
CAS :Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Formule :C26H36Cl2N8ODegré de pureté :97.40%Couleur et forme :SolidMasse moléculaire :547.52CCT241533 hydrochloride
CAS :CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).Formule :C23H28ClFN4O4Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :478.95Ref: TM-T10718L
1mg73,00€2mg96,00€5mg159,00€10mg240,00€25mg515,00€50mg852,00€100mg1.264,00€500mg2.547,00€1mL*10mM (DMSO)170,00€DMT-dU-CE Phosphoramidite
CAS :DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.Formule :C39H47N4O8PDegré de pureté :97.58%Couleur et forme :SolidMasse moléculaire :730.79BMS-1001
CAS :BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formule :C35H34N2O7Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :594.7Abciximab
CAS :Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaVotoplam HCl
CAS :Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).Formule :C21H26ClN9ODegré de pureté :99.49%Couleur et forme :SoildMasse moléculaire :455.94
