Antimétabolite nucléosidique/analogue
Les antimétabolites et analogues des nucléosides sont des composés qui imitent les nucléosides naturels et sont incorporés dans l'ADN lors de la réplication, entraînant la terminaison de la chaîne ou l'inhibition de la synthèse de l'ADN. Ces composés sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des infections virales. En perturbant la synthèse de l'ADN, les analogues des nucléosides induisent l'arrêt du cycle cellulaire et l'apoptose. Chez CymitQuimica, nous offrons une large gamme d'antimétabolites et d'analogues de nucléosides de haute qualité pour soutenir vos recherches sur le traitement du cancer, la thérapie antivirale et la réplication de l'ADN.
Produits appartenant à la catégorie "Antimétabolite nucléosidique/analogue"
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SIBA
CAS :SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Formule :C14H21N5O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :339.41Ref: TM-T12908
1mg52,00€5mg94,00€10mg117,00€25mg220,00€50mg329,00€100mg469,00€200mg652,00€1mL*10mM (DMSO)104,00€2'-Deoxy-2'-fluorocytidine
CAS :2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Formule :C9H12FN3O4Degré de pureté :99.03%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :245.215-Bromo-2',3',5'-tri-O-acetyluridine
CAS :5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.21Ascamycin
CAS :Ascamycin: a Streptomyces-made antibiotic targeting Xanthomonas spp. MIC: 0.4-12.5 μg/mL for X. citri, oryzae, and phage.Formule :C13H18ClN7O7SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :451.84Ref: TM-T14329
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)747,00€Netivudine
CAS :Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.Formule :C12H14N2O6Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :282.255-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.79%Couleur et forme :Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :244.23'-Deoxy-3'-fluoroadenosine
CAS :3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFormule :C10H12FN5O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :269.23CNDAC hydrochloride
CAS :CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.Formule :C10H13ClN4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :288.69Ref: TM-T13621
1mg114,00€5mg274,00€10mg425,00€25mg702,00€50mg938,00€100mg1.311,00€1mL*10mM (DMSO)250,00€RX-3117
CAS :RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.Formule :C10H12FN3O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :257.22Ref: TM-T16813
1mg157,00€2mg212,00€5mg309,00€10mg444,00€25mg728,00€50mg1.017,00€100mg1.378,00€1mL*10mM (DMSO)319,00€N6-(p-Methoxybenzyl)adenosine
CAS :Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.39Uridine triphosphate 13C9,15N2 sodium
CAS :Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04Ganciclovir sodium
CAS :Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formule :C9H13N5NaO4Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :278.222'-Fluoro-2'-Deoxyadenosine
CAS :2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formule :C10H12FN5O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :269.232'-Deoxy-5,6-dihydrouridine
CAS :2'-Deoxy-5,6-dihydrouridine is a nucleoside analog that contains a dihydro group in its molecular structure,commonly used in base excision related studies.Formule :C9H14N2O5Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :230.229-(β-D-Xylofuranosyl)adenine
CAS :9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormule :C10H13N5O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :267.24DMT-dG(ib) Phosphoramidite
CAS :DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formule :C44H54N7O8PDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :839.92DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS :DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formule :C41H49N4O9PDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :772.822'-O-(2-Azidoethyl)adenosine
CAS :2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity.Formule :C12H16N8O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :336.31Dacarbazine
CAS :Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.Formule :C6H10N6ODegré de pureté :99.78%Couleur et forme :Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)Masse moléculaire :182.182'-O-Methyl-2-thiouridine
CAS :2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Formule :C10H14N2O5SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :274.292'-O-Methylinosine
CAS :2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally bioavailable purine nucleoside analog with antihypertensive activity.Formule :C11H14N4O5Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :282.256-AZATHYMINE
CAS :6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Formule :C4H5N3O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :127.1Sangivamycin
CAS :Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Formule :C12H15N5O5Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :309.28Ref: TM-T9605
1mg126,00€5mg274,00€10mg416,00€25mg677,00€50mg944,00€100mg1.264,00€1mL*10mM (DMSO)360,00€5,6-Dihydro-5-methyluracil
CAS :5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.Formule :C5H8N2O2Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :128.13Decitabine
CAS :Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.Formule :C8H12N4O4Degré de pureté :98.06% - 99.87%Couleur et forme :Physical Description Fine White Crystalline Powder Used As A DrugMasse moléculaire :228.212',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS :2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication,AIDS and herpes.Formule :C21H40N2O6Si2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :472.72Ref: TM-TNU1182
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€3-Deazauridine
CAS :3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Formule :C10H13NO6Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :243.21GS-443902
CAS :Remdesivir triphosphate (GS-443902) inhibits RSV/HCV RdRp with IC50s: 1.1/5 µM.Formule :C12H16N5O13P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.25-BrdU
CAS :5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.Formule :C9H11BrN2O5Degré de pureté :99.54% - 99.87%Couleur et forme :Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :307.1Lobucavir
CAS :Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).Formule :C11H15N5O3Couleur et forme :SolidMasse moléculaire :265.275-OHdU
CAS :5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.Formule :C9H12N2O6Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :244.2Ref: TM-T19152
1mg47,00€2mg60,00€5mg89,00€10mg131,00€25mg212,00€50mg316,00€100mg474,00€1mL*10mM (DMSO)90,00€Adenosine
CAS :Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.Formule :C10H13N5O4Degré de pureté :98.76% - 99.86%Couleur et forme :Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Masse moléculaire :267.24Deoxycytidine triphosphate trisodium salt
CAS :Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.Formule :C9H13N3Na3O13P3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :533.1Trifluridine/tipiracil hydrochloride mixture
CAS :Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in aFormule :C29H34Cl2F6N8O12Degré de pureté :99.37% - ≥98%Couleur et forme :SolidMasse moléculaire :871.53Ref: TM-T3658
2mg39,00€5mg57,00€10mg87,00€25mg157,00€50mg250,00€100mg378,00€200mg568,00€500mg889,00€1mL*10mM (DMSO)78,00€Ac-rC Phosphoramidite
CAS :Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.Formule :C47H64N5O9PSiDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :902.18-Azahypoxanthine
CAS :8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.Formule :C4H3N5ODegré de pureté :≥98%Couleur et forme :Light Yellow To Light Beige Fine CrystallineMasse moléculaire :137.1Ref: TM-T20102
5mg48,00€10mg66,00€25mg104,00€50mg154,00€100mg216,00€200mg324,00€1mL*10mM (DMSO)48,00€Rabacfosadine
CAS :Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Formule :C21H35N8O6PDegré de pureté :98.75% - 99.43%Couleur et forme :SolidMasse moléculaire :526.535-Methylcytidine
CAS :5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.Formule :C10H15N3O5Degré de pureté :99.02% - 99.88%Couleur et forme :SolidMasse moléculaire :257.242'-OMe-Guanosine
CAS :2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.Formule :C11H15N5O5Degré de pureté :98.92%Couleur et forme :White SolidMasse moléculaire :297.278-Chloroinosine
CAS :8-Chloroinosine is a purine nucleoside analog and a metabolite of the anticancer compound 8-chloro-adenosine.Formule :C10H11ClN4O5Degré de pureté :99.37% - 99.56%Couleur et forme :SolidMasse moléculaire :302.671-Methylinosine
CAS :1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.Formule :C11H14N4O5Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :282.25DL-Alanosine
CAS :DL-Alanosine is an amino acid analog with antitumor activity.Formule :C3H7N3O4Couleur et forme :SolidMasse moléculaire :149.105N1-Methylpseudouridine
CAS :N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms byFormule :C10H14N2O6Degré de pureté :100% - 99.14%Couleur et forme :SolidMasse moléculaire :258.23Bredinin aglycone
CAS :Bredinin aglycone (SM-108) is a purine nucleotide analog.Formule :C4H5N3O2Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :127.15-Aminouridine
CAS :5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.Formule :C9H13N3O6Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :259.222'-Deoxy-2'-fluoroarabinoadenosine
CAS :2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.Formule :C10H12FN5O3Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :269.232',5-Difluoro-2'-deoxy-1-arabinosyluracil
CAS :2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepilepticFormule :C9H10F2N2O5Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :264.185'-O-DMT-N2-ibu-dG
CAS :5'-O-DMT-N2-ibu-dG is a deoxynucleoside served as a building block in oligonucleotide synthesis, with protecting groups to prevent unwanted reactions.Formule :C35H37N5O7Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :639.7N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
CAS :N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity.Formule :C47H52N7O7PDegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :857.93Ref: TM-TNU1119
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€500mg3.734,00€DMT-2′Fluoro-dU Phosphoramidite
CAS :DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Formule :C39H46FN4O8PDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :748.78
