Antimétabolite nucléosidique/analogue
Les antimétabolites et analogues des nucléosides sont des composés qui imitent les nucléosides naturels et sont incorporés dans l'ADN lors de la réplication, entraînant la terminaison de la chaîne ou l'inhibition de la synthèse de l'ADN. Ces composés sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des infections virales. En perturbant la synthèse de l'ADN, les analogues des nucléosides induisent l'arrêt du cycle cellulaire et l'apoptose. Chez CymitQuimica, nous offrons une large gamme d'antimétabolites et d'analogues de nucléosides de haute qualité pour soutenir vos recherches sur le traitement du cancer, la thérapie antivirale et la réplication de l'ADN.
Produits appartenant à la catégorie "Antimétabolite nucléosidique/analogue"
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Cytidine
CAS :Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond.Formule :C9H13N3O5Degré de pureté :98.80% - 99.63%Couleur et forme :Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :243.22N,N-Dimethyl-2'-O-methylcytidine
CAS :N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.Formule :C12H19N3O5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :285.32'-O-Methyl-5-iodouridine
CAS :2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses aFormule :C10H13IN2O6Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :384.12Deoxycytidine triphosphate
CAS :dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.Formule :C9H16N3O13P3Degré de pureté :95.19%Couleur et forme :SolidMasse moléculaire :467.16N2-Methylguanosine
CAS :N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA'sFormule :C11H15N5O5Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :297.27Gemcitabine hydrochloride
CAS :Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66Tipiracil hydrochloride
CAS :Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Formule :C9H12Cl2N4O2Degré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :279.12Tiazofurin
CAS :Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formule :C9H12N2O5SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :260.27Ref: TM-T40686
1mg150,00€5mg304,00€10mg437,00€25mg677,00€50mg900,00€100mg1.225,00€200mg1.644,00€1mL*10mM (DMSO)284,00€Cytarabine
CAS :Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Dihydro-5-azacytidine acetate
CAS :Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1Formule :C10H18N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.275-Hydroxyuridine
CAS :5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.Formule :C9H12N2O7Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :260.2Gemcitabine
CAS :Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4Degré de pureté :100% - 99.67%Couleur et forme :SolidMasse moléculaire :263.2LNA-Adenosine
CAS :LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.Formule :C11H13N5O4Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :279.25Pseudouridine
CAS :Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.Formule :C9H12N2O6Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :244.2Enocitabine
CAS :Enocitabine is a nucleoside analog.Formule :C31H55N3O6Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :565.78L-Uridine
CAS :L-Uridine, an RNA component from Poria cocos fungus, is a D-uridine enantiomer with antiviral potential and a phosphate acceptor.Formule :C9H12N2O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :244.2Carmofur
CAS :Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Formule :C11H16FN3O3Degré de pureté :98.59% - 99.48%Couleur et forme :SolidMasse moléculaire :257.265-Ethynyluridine
CAS :5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formule :C11H12N2O6Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :268.22Ref: TM-T36971
5mg51,00€10mg88,00€25mg145,00€50mg250,00€100mg363,00€200mg545,00€1mL*10mM (DMSO)57,00€Orotic acid zinc
CAS :Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.Formule :C10H6N4O8ZnDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :188.795-(Methoxycarbonyl)methyluridine
CAS :5-(Methoxycarbonyl)methyluridine is an important modifying nucleotide in tRNAs, and the lack of the mcm5U modification leads to increased protein aggregation.Formule :C12H16N2O8Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :316.263'-Deoxy-3'-fluoroguanosine
CAS :3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons.Formule :C10H12FN5O4Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :285.23Gemcitabine elaidate
CAS :Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, withFormule :C27H43F2N3O5Couleur et forme :SolidMasse moléculaire :527.642',3'-Isopropylideneuridine
CAS :2',3'-Isopropylideneuridine is a nucleoside derivative that has shown antiviral activity in several studies, particularly against Flaviviruses, such as HCV.Formule :C12H16N2O6Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :284.27(S)-GNA-T-phosphoramidite
CAS :(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Formule :C38H47N4O7PDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :702.785'-Azido-5'-deoxythymidine
CAS :5'-Azido-5'-deoxythymidine is a nucleoside analog with potential anti-tuberculosis activity and an inhibitor of TMPKmt in Mycobacterium tuberculosis.Formule :C10H13N5O4Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :267.24Ethynylcytidine
CAS :Ethynylcytidine is a nucleoside antimetabolite.Formule :C11H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.24N6-Methyl-2'-O-methyladenosine
CAS :N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFormule :C12H17N5O4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :295.29N6-Methyladenine
CAS :N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.Formule :C6H7N5Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :149.152′-C-Methyl-6-O-methylinosine
CAS :6-MeO-9-(2-C-methyl-β-D-ribofuranosyl)purine is a hypoxanthine analog used in tumor disease research.Formule :C12H16N4O5Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :296.28Peldesine
CAS :Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Formule :C12H11N5ODegré de pureté :99.27% - 99.95%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T12399
1mg114,00€5mg274,00€10mg439,00€25mg727,00€50mg1.017,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)303,00€8-Azaguanine
CAS :8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.Formule :C4H4N6ODegré de pureté :100% - 99.89%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :152.112'-Deoxycytidine hydrochloride
CAS :2'-Deoxycytidine hydrochloride is an important deoxyribonucleoside analog and protects mice from the lethal toxicity of cytosine arabinoside(araC).Formule :C9H14ClN3O4Degré de pureté :98.96%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :263.68LY2334737
CAS :LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formule :C17H25F2N3O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :389.39Ref: TM-T4061
1mg62,00€5mg131,00€10mg205,00€25mg378,00€50mg562,00€100mg777,00€200mg1.074,00€1mL*10mM (DMSO)166,00€dGTP
CAS :dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormule :C10H16N5O13P3Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :507.18Triazavirin
CAS :Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formule :C5H7N6NaO5SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :286.22',3'-Dideoxyuridine
CAS :2',3'-Dideoxyuridine is a purine nucleoside analog with potential antitumor activity.Formule :C9H12N2O4Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :212.2Nelarabine
CAS :Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Formule :C11H15N5O5Degré de pureté :97.90% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Ref: TM-T6603
1mg43,00€2mg57,00€5mg88,00€10mg140,00€25mg246,00€50mg437,00€100mg550,00€500mg1.159,00€1mL*10mM (DMSO)88,00€5-Aza-7-deazaguanine
CAS :5-Aza-7-deazaguanine is a non-natural substituted nucleobase with potential antiviral activity, used in cancer and bacterial infection research.Formule :C5H5N5ODegré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :151.135'-O-DMT-N4-Bz-5-Me-dC
CAS :5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formule :C38H37N3O7Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :647.72N-6-Furfurylguanosine
CAS :N-6-Furfurylguanosine (kinetin riboside) is a purine nucleoside analog with cytotoxicity, inhibiting the growth of cancer cells.Formule :C15H18N6O5Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :362.34Uridine-5-acetic acid
CAS :Uridine-5-acetic acid (5-Carboxymethyluridine) is a nucleoside formed during RNA transfer processes in yeast and wheat embryos.Formule :C11H14N2O8Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :302.248-Bromoadenosine
CAS :8-Bromoadenosine is an adenosine derivative. 8-Br-Adenosine inhibitis mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.Formule :C10H12BrN5O4Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.14Capecitabine
CAS :Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.Formule :C15H22FN3O6Degré de pureté :100% - 99.89%Couleur et forme :Less Solid Colourless SolidMasse moléculaire :359.35Ganciclovir
CAS :Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.Formule :C9H13N5O4Degré de pureté :99.4% - 99.55%Couleur et forme :White PowderMasse moléculaire :255.23Deoxyguanosine triphosphate trisodium salt
CAS :Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can beFormule :C10H13N5Na3O13P3Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :573.137-Methylxanthine
CAS :7-Methylxanthine, a xanthine methyl derivative, prevents FDM by altering the sclera in rabbits. It's a purine in kidney stones.Formule :C6H6N4O2Degré de pureté :97.66% - 98.58%Couleur et forme :SolidMasse moléculaire :166.146-Mercaptopurine hydrate
CAS :6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.Formule :C5H6N4OSDegré de pureté :97.54% - 99.14%Couleur et forme :Light Yellow Crystalline PowderMasse moléculaire :170.19Stavudine
CAS :Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.Formule :C10H12N2O4Degré de pureté :100% - 99.74%Couleur et forme :White PowderMasse moléculaire :224.21S-Gem
CAS :S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.Formule :C13H15F2N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.42'-Deoxy-N4-methylcytidine
CAS :2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Formule :C10H15N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :241.24
