Enzyme

Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate

Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family.

E3 ubiquitin ligase.

AK3L1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

STEAP2 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is Q8NFT2.

ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E.

Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of

Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase

Catalyzes two steps in the degradation of uric acid, i.e.

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family.

Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.

Entorokinase (also known as enteropeptidase; EC 3.4.21.9) is a proteolytic enzyme (proteinase) that activates trypsinogen into its active form, trypsin. One unit of  Entorokinase will produce 1.0 nmole of trypsin from trypsinogen per min at pH 5.6 and 25 °C.

Phospholipases D belong to the family of esterases and act on phosphatidylcholine in the plasma membrane to release phosphatidic acid (PA) and choline. Phospholipases D can be used as versatile tools in hydrolysis and transphosphatidylation reactions for industrial, chemical and food applications.Spray dried version of EPLD840.6_R

ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family.

CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.

One unit of Aminopeptidase (3.4.11.10) will hydrolyze 1.0 μmole of L-leucine p-nitroanilide to p-nitroaniline and L-leucine per min at pH 8.0 and 25 °C.

METAP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

AADAC Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with C-10xHis. The accession number is P22760.

IL-1RAPL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Bromelain is a group of proteolytic enzymes found in the fruit and stem of pineapple plants. It is used in a topical drug product approved by the FDA to treat severe burns. However, its oral consumption to treat sinusitis, postoperative pain after the extraction of wisdom teeth, and osteoarthritis is still being researched.

LIPF Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.

Thiol protease which is believed to participate in intracellular degradation and turnover of proteins.

Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to

Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors.

PPIases accelerate the folding of proteins.

GDP-L-Fucose Synthase is a NADP(H)-binding protein.

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.

Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.

Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline.

GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) is expressed in E. coli.

Papain Protein, Carica papaya, Recombinant (His) is expressed in E.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The CalB02 ICE lipase has been immobilized on a hydrophobic carrier by a covalent linkage. The immobilized CalB02 lipase has a temperature optimum in the 40 - 50 °C range and pH optimum between pH 5 and 8.

Acts against tyrosine-phosphatases.

Stores iron in a soluble, non-toxic, readily available form.

PRKAA1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-6xHis tag.

PLA2G15 Protein, Canine, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

TLK2 Protein, Human, Recombinant (aa 397-772, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Toxic component of a type II toxin-antitoxin (TA) system.

Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec.

7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC

Pegloticase is a PEGylated urate oxidase enzyme used to treat chronic granulomatous disease. It is also a methyltransferase inhibitor that prevents the activation of bacterial enzymes, such as cytosine-guanine dinucleotide phosphate (CpG) methyltransferase. This enzyme catalyses the methylation of CpG sites on DNA, which are important for maintaining normal gene expression. Pegloticase has been shown to be effective in reducing the activity of inflammatory bowel disease and rheumatoid arthritis. It also has been shown to have pharmacological effects on congestive heart failure, hypersensitivity syndrome, and bowel diseases due to its anti-inflammatory properties. Pegloticase has not been studied in patients with hepatic impairment or taking nonsteroidal anti-inflammatory drugs.

ALDH1A3 Protein, Mouse, Recombinant (His) is expressed in E.

DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures.

Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms,

ENTPD3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins.

Enteropeptidase (historic name entorokinase; EC 3.4.21.9) is a proteolytic enzyme (proteinase) that activates trypsinogen into its active form, trypsin. One unit of enteropeptidase will produce 1.0 nmole of trypsin from trypsinogen per min at pH 5.6 and 25 °C.

HTRA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.50 kDa and the accession number is Q92743.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate

Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other

This protein functions as a defense against chitin-containing fungal pathogens.

GSK3B Protein, Human, Recombinant (E.

CES1D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His) is expressed in E.

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

DUSP3 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 20.6 kDa and the accession number is P51452.

P4HA1 Protein, Human, Recombinant (His) is expressed in E. coli.

Protease that has a low substrate specificity.

Nitrile hydratase 20 recombinantly expressed in E. coli comes in a freeze-dried formulation. Nitrile hydratases can be utilized to convert nitriles into their corresponding amides, e.g. to produce acrylamide from acrylonitrile. Additional applications include the removal of nitriles from industrial wastewater. Our nitrile hydratases have been tested for hydrolysis of the following substrates:cyclohexanecarbonitrile, cinnamonitrile, benzonitrile, methacrylonitrile, pivalonitrile.

Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.

FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis.

PML Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease.

E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.

AtAER Protein, Arabidopsis thaliana, Recombinant is expressed in E.

Lipase 09 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7 and temp. optimum at 35-55°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 09 was shown to hydrolyze p-Nitrophenyl esters of acetate (18 % activity compared to octanoate), butyrate (80 %), octanoate (100 %) and capate (40 %).

TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes.

Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase.

Aldolase C Protein, Mouse, Recombinant (His) is expressed in Yeast.

The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma.

VEGFR3/FLT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Sialic acid aldolase - crystalline is a purified enzyme product, which is typically derived from microbial sources, such as certain bacteria, that have evolved to metabolize sialic acids. This enzyme catalyzes a reversible aldol reaction between sialic acid and pyruvate, facilitating the cleavage or formation of sialic acid from N-acetylmannosamine and pyruvate. By breaking the carbon-carbon bond in sialic acid, sialic acid aldolase plays a critical role in the degradation and biosynthesis pathways of sialic acid, which are key factors in numerous biological processes. The enzyme has significant applications in biochemical research, particularly in the study of metabolic pathways involving sialic acids, which are essential components of glycoproteins and glycolipids in animal tissues. It is also utilized in synthetic biology for the bioengineering of sialic acid-related compounds, enabling the design of novel biomolecules with potential therapeutic value. Understanding the functionality of sialic acid aldolase is crucial for scientists investigating cellular interactions, viral infections, and immune responses, given the prominence of sialic acids in cellular recognition processes.

Proteinase, Bacillus subtilis, sutilain is a proteolytic enzyme, which is derived from the bacterium Bacillus subtilis. This enzyme exhibits a serine-type mechanism of action, characterized by its ability to cleave peptide bonds in proteins efficiently. It catalyzes the hydrolysis of proteins into peptides and amino acids, facilitating the breakdown of complex proteins into simpler, soluble forms. The uses and applications of Proteinase, Bacillus subtilis, sutilain are diverse due to its robust proteolytic capabilities. It is widely employed in various industrial processes, including the food and detergent industries, where it aids in the breakdown of proteinaceous materials. In the pharmaceutical and research sectors, it is utilized for protein digestion in peptide mapping, protein sequencing, and in the preparation of protein hydrolysates for nutritional and therapeutic purposes. Its stability under a range of conditions makes it a versatile tool for laboratory and industrial settings, enabling advances in protein engineering and bioprocess optimization.

Please enquire for more information about Heat Labile Uracil-DNA Glycosylase, 500 units including the price, delivery time and more detailed product information at the technical inquiry form on this page

PCSK9 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The predicted molecular weight is 73.03 kDa and the accession number is Q8NBP7.

PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family.

PSMB8 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.

LARGE1 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is O95461.

Maltose phosphorylase (systematic name maltose:phosphate 1-beta-D-glucosyltransferase; EC 2.4.1.8) is an enzyme that catalyzes the following reaction:  maltose + Pi ⇌ D-glucose + beta-D-glucose 1-phosphate  One unit of maltose phosphorylase will produce 1.0 μmole of D-Glucose from maltose per minute at pH 7.0 and 30°C.

Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions,

FTCD Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas.

GBA Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.

PLK1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene.

Catalyzes the conversion of L-arabinose to L-ribulose.

CHIT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9D7Q1.

NADP-ME Protein, Human, Recombinant (His) is expressed in E.

Aconitase 2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

N/A.

Beta Amylase/AMY2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Kallikrein 11/KLK11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

N/A.

Histone-lysine N-methyltransferase, H3 lysine-79 specific, also known as Histone H3-K79 methyltransferase, DOT1-like protein, Lysine N-methyltransferase 4 and

TrkB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation.

Porcine liver esterase (EC 3.1.1.1) is an enzyme that catalyses ester hydrolysis, producing a fatty acid and an alcohol. One unit of esterase will hydrolyze 1.0 μmole of ethyl butyrate to butyric acid and ethanol per min at pH 8.0 and 25 °C. Ethyl butyrate is available here.

Active on 2-DOG-6P, also very active on fructose-1P.

SUCLA2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q9P2R7.

ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Glutaminyl cyclase, also known as QPCT, can promote the N-terminal cyclization reaction of N-terminal pyroglutamate(pGlu).

D-Ribulose 1,5-diphosphate carboxylase, commonly known as RuBisCO, is an essential enzyme that catalyzes the first major step of carbon fixation, a process by which inorganic carbon from the atmosphere is converted into organic molecules. This enzyme is derived from spinach, a common model organism used in plant biology research due to its accessibility and well-characterized photosynthetic pathways. RuBisCO operates by catalyzing the reaction of carbon dioxide with ribulose-1,5-bisphosphate (RuBP) to form two molecules of 3-phosphoglycerate. This reaction constitutes a crucial part of the Calvin cycle, which takes place in the chloroplasts of plant cells. As the most abundant protein on Earth, RuBisCO plays a critical role in the conversion of carbon dioxide into organic compounds, ultimately supporting the food chain through its foundational role in photosynthesis. Given its pivotal role, RuBisCO is of great interest in studies involving photosynthetic efficiency, plant biochemistry, and strategies to enhance crop yield. Researchers often explore its structural properties, kinetics, and potential for genetic engineering to improve its catalytic efficiency to meet global food demands and address climate change challenges.

TrkA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Muscle, skeletal receptor tyrosine-protein kinase, also known as Muscle-specific tyrosine-protein kinase receptor, Muscle-specific kinase receptor, and MUSK, is

GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.

Protocatechuate 3,4-dioxygenase is a bacterial enzyme, which is sourced from Pseudomonas sp. This enzyme operates by catalyzing the cleavage of aromatic rings in protocatechuate, a derivative of catechol. Its mode of action involves the incorporation of oxygen into protocatechuate, resulting in the formation of beta-carboxy-cis,cis-muconate. This reaction is crucial for the microbial degradation of aromatic compounds, thereby playing a significant role in the biodegradation pathways of lignin-derived aromatic pollutants. Widely studied for its significance in environmental bioremediation, protocatechuate 3,4-dioxygenase is key to breaking down complex organic materials in soil and water ecosystems. Its applications extend to industrial processes where the enzymatic transformation of aromatic compounds is required, such as in the synthesis of bio-based chemicals. Researchers also investigate its potential in metabolic engineering to enhance microbial strains for efficient degradation of environmental pollutants. Understanding and utilizing this enzyme can significantly contribute to advances in biotechnology and ecological sustainability.

PLA2G1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.

Cell wall formation.

Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity.

Neuraminidase (Exo-α-sialidase, sialidase, systematic name acetylneuraminyl hydrolase; EC 3.2.1.18) is an enzyme that catalyzes hydrolysis of glycosidic linkages of neuraminic acids. As it is exo-hydrolase, it hydrolyzes terminal N- or O- acylneuramic acid units, that are linked by α2,3-, α2,6-, and α2,8- glycosidic bonds. One unit of neuraminidase will hydrolyze 1 μmol N-acetyl-neuraminosyl-D-lactose under optimal conditions.

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

Lipase 65 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7-8 and temp. optimum at 30-40°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 65 was shown to hydrolyze p-Nitrophenyl esters of butyrate (100 % activity), octanoate (87 %), laurate (5 %), palmitate (0.2 %) and stearate (0.1 %).