Enzyme

Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during

PIK3CG Protein, Human, Recombinant (His & Myc) is expressed in E.

Butyrylcholinesterase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Mer Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.

HDAC4 (histone deacetylase 4), belongs to class II of the histone deacetylase/AcuC/APhA family.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors,

TIGAR Protein, Human, Recombinant (TAT) is expressed in E. coli with C-TAT. The accession number is Q9NQ88.

Lipase 17 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7-8. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 17 was shown to hydrolyze p-Nitrophenyl esters of butyrate (2 % activity compared to octanoate), octanoate (100 %), laurate (20 %), palmitate (3 %), stearate (1 %), arachidate (1 %) and behenate (1 %).

Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and

Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to

Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that

Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.

Phospholipase A2, liquid, food-grade, is an enzymatic product derived from natural sources, typically microbial or animal tissues, utilized in various lipid modification processes. This enzyme specifically targets phospholipids, catalyzing the hydrolysis of the sn-2 ester bond, which releases free fatty acids and lysophospholipids. Its precise and efficient mode of action allows for targeted alterations in the lipid structure, offering potential benefits in modifying texture, flavor, and stability of food products. In food technology and research, Phospholipase A2 is employed to enhance the processing and quality of a wide array of food items. Its applications include the modification of fats in dairy products, improvement of dough properties in baking, and the enhancement of oil extraction and refining processes. By breaking down specific phospholipids, this enzyme helps in reducing rancidity and improving the emulsification properties of food products, thereby extending shelf life and optimizing texture in end products. Its specificity and effectiveness make it a valuable tool for scientists exploring innovative solutions in food processing and quality improvement.

Granzyme K/GZMK Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

CYLD Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q80TQ2.

D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO) is expressed in E.

Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family.

Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate.

SUC2 Protein, Saccharomyces cerevisiae, Recombinant (His) is expressed in yeast with His tag.

PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

A trypsin product which can be used as a standard in proteomics procedures such as mass spectrometry. Trypsin (EC 3.4.21.4) is a protease that hydrolyses proteins by cleaving the peptide bond at the carboxyl side of the positively charged amino acid (Lysine or Arginine). Trypsin belongs to a family of serine proteases, as it has a serine in its active site. Trypsin can be inhibited by using trypsin inhibitor Alpha 1 Antitrypsin.

Participates in a DNA-damage check-point.

Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein

3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) is a metabolite that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid.

GPD1 Protein, Mouse, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is P13707.

Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

Pappalysin-2/PAPP-A2 is the second member of the pappalysin family of metzincin superfamily, of which PAPP-A is the first member.

IL-1RAPL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α

RAB10 Protein, Human, Recombinant (His) is expressed in E. coli.

TOP1 Protein, Mouse, Recombinant (aa 193-767, His) is expressed in Baculovirus-Insect Cells. The accession number is Q04750.

PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family.

Has DNA hydrolytic activity.

Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family.

Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal

Isoamylase (also known as debranching enzyme, systemic name glycogen α-1,6-glucanohydrolase; EC 3.2.1.68) is an enzyme from the family of carbohydrolases acting specifically on α-1,6-glucosidic branch linkages in polysaccharides such as amylopectin or glycogen, but rarely hydrolyzes such bonds in pullulan. Isoamylase has been obtained from P. amyloderamosa and has a temperature optimum in the 30 - 40 °C range and pH optimum between pH 3 and 4.

IL-1R1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.8 kDa and the accession number is P14778.

Proteinase K is used for the general digestion of proteins and removal of protein contamination in nucleic acids. Addition of Protease K also stabilizes nucleic acids by degrading any nucleases present. Proteinase K is active in wide range of pH range, in the presence of SDS, urea and Guanidinium chloride at low to moderate concentrations. Proteinase K is also known under names of protease K and endopeptidase K.

Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes,

Alpha Amylase is an enzyme that catalyses hydrolysis of large polysacharides into smaller fragments. Alpha amylase targets alpha bonds of 1→4 glycosidic linkages of poly- and oligosaccharides with three or more D-glucose units. Systematic name of alpha-amylase is 4-α-D-glucan glucanohydrolase, EC 3.2.1.1. One unit of Alpha Amylase will produce 1.0 mg of maltose from starch in 1 minute at pH 4.9 and 40 °C.

Cleaves the glycosidic bonds of gellan backbone and releases tetrasaccharide units of glucuronyl-glucosyl-rhamnosyl-glucose with unsaturated glucuronic acid at

FabB Protein, E.

Carboxypeptidase M Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,

D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT

Lipase 38 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at >50°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 38 was shown to hydrolyze p-Nitrophenyl esters of acetate (27 % activity compared to butyrate), butyrate (100 %), octanoate (9 %) and caprate (5 %).

Nitrilase (nitrile aminohydrolase; EC 3.5.5.1) in an enzyme that catalyzes hydrolysis of nitriles to carboxilic acids and ammonia:  R-CN + 2 H2O → R-COO- + NH4+  One unit of nitrilase will yield 1.0 μmol of ammonia per minute under optimal reaction conditions using acrylonitrile as a substrate.

Peroxiredoxin 5 Protein, Mouse, Recombinant (His) is expressed in E.

Pyridoxal kinase Protein, Human, Recombinant (GST) is expressed in E. coli with N-GST. The accession number is O00764.

Poly(ethylene terephthalate) hydrolase is an enzyme involved in the breakdown of Polyethylene terephthalate which is present in many plastics Polyethylene terephthalate hydrolytic enzymes may be useful in biotechnology, for use in waste treatment, biocatalysis and biorecycling

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative

Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).

ECM31 Protein, S.

Aspartic acid proteinase is a type of proteolytic enzyme, which originates from various biological sources including humans, fungi, and plants. It is characterized by its action via two critical aspartic acid residues in the active site, which facilitate the hydrolysis of peptide bonds in proteins. This enzyme operates optimally in acidic environments, making it crucial in processes like digestion and protein processing within cellular compartments such as lysosomes. In scientific research, aspartic acid proteinases are extensively studied for their role in physiological processes and their potential as therapeutic targets. For instance, they are involved in the maturation of viral proteins, hence playing a pivotal role in the life cycle of certain viruses. Additionally, they are implicated in disease states such as Alzheimer’s due to their involvement in amyloid precursor protein processing. Applications of aspartic acid proteinases extend to industrial processes like cheese production, where they assist in milk protein coagulation. Understanding their mechanism and specificity aids in the development of inhibitors that can regulate their activity, presenting significant implications in both therapeutic contexts and biotechnological innovations.

Aminopeptidase N/CD13 Protein, Pig, Recombinant (His & Myc) is expressed in E.

ACE2 Protein, Paguma larvata, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.

Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN.

BRCC3 Protein, Mouse, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P46737.

Lipase 16 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7-8 and temp. optimum at >40°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 16 was shown to hydrolyze p-Nitrophenyl esters of butyrate (58 % activity compared to octanoate), octanoate (100 %), laurate (40 %), palmitate (27 %), stearate (13 %), arachidate (2 %) and behenate (0.2 %).

IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene.

Cathepsin S Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of

Thrombopoietin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

N/A.

Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides.

Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans.

Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.

Urokinase (urokinase-type plasminogen activator, uPA; EC 3.4.21.73) is as serine protease. Its physiological substrate is plasminogen. Urokinase converts plasminogen into an active enzyme, plasmin, which is also a serine protease. In its active form plasmin plays an important role in dissolving blood clots. Despite its name, Urokinase is not a kinase.

Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density

The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic

Glutamine Synthetase reglutes intracellular concentration of glutamate.

NLRP1 Protein, Human, Recombinant (GST) is expressed in E.

MUSK Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli.

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt

Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-

Carboxypeptidase B is an enzyme responsible for the cleavage of arginine and lysine from a peptide's C-terminus

p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

CCR5 Protein, Mouse, Recombinant (His) is expressed in P. pastoris (Yeast) with N-6xHis. The accession number is P51682.

Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family.

CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants.

Cleaves peptides in various proteins in a process that requires ATP hydrolysis.

Alkaline phosphatase that can hydrolyze various phosphate compounds.

N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene.

GAPDH Protein, Chicken, Recombinant (His) is expressed in E.

Ectonucleotide pyrophosphatase-phosphodiesterase 3 (ENPP3), a protein detected in the human uterus, has been found to play an important role in the development

Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids.

Adenosine deaminase catalyzes deamination of adenosine, converting it to inosine. It happens by the substituting of the amino group by a keto group. One Unit of the enzyme converts one micromole of adenosine to inosine per minute at 25°C, pH 7.4. Adenosine deaminase is also known by names of adenosine aminohydrolase, and ADA, EC 3.5.4.4.

Responsible for the proteolytic maturation of the alpha-factor precursor.

Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E.

ALDH1A1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli with N-6xHis. The accession number is P24549.

HDAC3 Protein, Human, Recombinant (His & SUMO) is expressed in E.

Phosphoglucomutase-2 (PGM2) is a member of PGM family, which catalyzes the inter-conversion of sugar phosphates and participates in anabolic and catabolic

DNA helicase which plays a role in chromatin-remodeling following DNA damage.

cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to

Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes.

Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein.

G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr

Carbonic Anhydrase 14 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 Cells. The accession number is Q9ULX7.

N/A.

Pyroglutamate aminopeptidase from Pyrococcus furiosus, recombinant from E. coli, is an enzymatic product that specifically targets N-terminal pyroglutamyl residues in peptide chains. This enzyme is derived from the hyperthermophilic archaeon Pyrococcus furiosus, which allows it to exhibit high thermal stability and activity across a broad range of temperatures. Being produced recombinantly in E. coli ensures consistent availability and purity suitable for scientific applications. The mode of action of this aminopeptidase involves the cleavage of pyroglutamyl residues from the N-terminus of peptides, facilitating subsequent analyses and modifications. This enzymatic activity is crucial because pyroglutamate formation can inhibit peptide processing and sequencing reactions, posing challenges in proteomics and protein characterization. Applications of Pyroglutamate aminopeptidase include its use in peptide sequencing workflows, where it enables or enhances the identification of protein and peptide structures by removing blocking pyroglutamyl groups. Its stability at high temperatures also makes it valuable in applications where heat-resistant enzymes are required, allowing for effective peptide modification under various experimental conditions.

FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.

SUMO protease, also known as Ulp, is a highly specific enzyme that removes small ubiquitin-like modifier (SUMO) from recombinant SUMO fusion proteins. Unlike proteases such as enterokinase or TEV, which recognize linear amino acid sequences, SUMO protease recognizes the native tertiary structure of SUMO, allowing precise cleavage without leaving extra residues at the cleavage site. This recombinant SUMO protease is derived from Saccharomyces cerevisiae, expressed in E. coli, and purified to obtain high yields of active enzyme under animal-free conditions. It is well suited for applications in drug and vaccine development, protein manufacturing, and other research uses. A C-terminal 6×His tag is included to enable easy removal of the protease following cleavage via Ni²⁺ affinity purification.

tPA Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 28 kDa and the accession number is P00750-1.

Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose.

Angiogenin belongs to the pancreatic ribonuclease family.

Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and

NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene.

AKR1C3, is an enzyme which belongs to the aldo/keto reductase family.

Genetic engineers have used glutathione S-transferase to create the GST gene fusion system.

Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial

The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric

Kallikrein 14 Protein, Mouse, Recombinant (His) is expressed in E. coli.

GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.