Enzyme

ENPP7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

E3 ubiquitin-protein ligase that mediates the ubiquitination of phosphorylated BCL2L11.

Lck Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P06239-1.

Candidapepsin-2 Protein, Candida albicans (strain WO-1), Recombinant (His) is expressed in E.

TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway.

Acetazolamide (Diamox) is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of acetazolamide is Sulfonamides.

Glucosyltransferase205-freeze dried is an enzyme preparation that is commonly used in biochemical and molecular biology research. It is derived from microbial sources, often from bacteria or fungi that are known for producing extracellular enzymes. The primary mode of action of Glucosyltransferase205 involves catalyzing the transfer of glucose residues from donor molecules, such as UDP-glucose, to acceptor molecules, forming glycosidic bonds. This enzymatic activity is crucial in the biosynthesis of polysaccharides, which are essential components in various biological structures and processes. In scientific research, Glucosyltransferase205-freeze dried is utilized for its ability to facilitate the study of glycosylation processes, which play a vital role in cell signaling, protein stabilization, and metabolic regulation. It is also employed in the synthesis of glycoconjugates and in the exploration of carbohydrate-active enzymes. Researchers often use this enzyme to investigate the mechanisms of polysaccharide formation, understand glycan diversity, and develop novel biotechnological applications, such as the production of bioactive compounds with potential therapeutic benefits. The freeze-dried form ensures stability and ease of storage, making it a convenient choice for laboratory settings.

Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the

Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin

NirK Protein, Rhizobium sullae, Recombinant (His) is expressed in E.

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-

Carbonic Anhydrase 8 Protein, Human, Recombinant (His) is expressed in E.

Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

SLFN11 Protein, Human, Recombinant (His) is expressed in E.

Butyrylcholinesterase (BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase; EC 3.1.1.8, CAS No [9001-08-5]) is an enzyme that made in the liver and found mainly in blood plasma. It catalyzes the following reaction: Acylcholine + H2O → choline + carboxylic acidOne unit of Butyrylcholinesterase will change absorbance by 0.2 milliunits (mA) per minute at optimal buffer conditions and 37 ̊C. Equine serum butyrylcholinesterase is supplied as white to pale grey-green powder with activity of ≥50U/mg and specific activity of ≥300U/mg protein. It can be dissolved at 5 mg/mL concentration in 50 mM Tris-HCl pH 7.3 - 7.5, giving colorless to slightly green solution. Equine serum butyrylcholinesterase is activated by Ca2+, optimum pH 7-8, KM=18 µM (butyrylthiocholine at 25°C). Store at -20°C on arrival.

Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide

SARM1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens.

Temocapril is an inhibitor of tyrosine kinase.

LacBuster® Settle Plates contain a general purpose growth medium (tryptone soya agar) supplemented with LacBuster®, a high-performing beta-lactamase to effectively neutralize beta-lactam antibiotics. The media plates are suitable for the cultivation of a wide variety of microorganisms in environmental monitoring within the pharmaceutical industry.

Please enquire for more information about CalB 01 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes.

6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene.

DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins.

Involved in transport from the endoplasmic reticulum to the Golgi apparatus.

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family.

EIF3F Protein, Human, Recombinant (His) is expressed in E.

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

USP46 Protein, Human, Mouse, Recombinant is expressed in Baculovirus insect cells.

Dextranase (alternative names dextran hydrolase, endo-dextranase, endodextranase, dextranase DL 2, α-D-1,6-glucan-6-glucanohydrolase, 1,6-α-D-glucan 6-glucanohydrolase, EC 3.2.1.11) is dextran-degrading enzyme that hydrolyzes the α(1→6) glycosidic linkage of dextran, cutting it into progressively shorter fragments, ultimaly producing isomaltose (a disaccharide) and glucose. One unit of dextranase will cleave dextrane to yield 1.0 μmole of isomaltose per min at pH 6.0 and 37 °C.

Key component in the assembly and functioning of vertebrate striated muscles.

Possible role in sperm motility.

The ubiquitin-conjugating enzyme E2B (Ube2b) is a critical target gene of androgen receptor (AR), mediating the function of AR in spermatogenesis by promoting

ABHD14B belongs to the AB hydrolase superfamily, ABHD14 family.

TrkA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

RAF1 gene is the cellular homolog of viral raf gene (v-raf).

Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the

May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.

SIRT5 Protein, Human, Recombinant (His) is expressed in E.

Nitrile hydratase 05 recombinantly expressed in E. coli comes in a freeze-dried formulation. Nitrile hydratases can be utilized to convert nitriles into their corresponding amides, e.g. to produce acrylamide from acrylonitrile. Additional applications include the removal of nitriles from industrial wastewater. Our nitrile hydratases have been tested for hydrolysis of the following substrates:cyclohexanecarbonitrile, cinnamonitrile, benzonitrile, methacrylonitrile, pivalonitrile.

4HbD Protein, Clostridium kluyveri, Recombinant (His & Myc) is expressed in E. coli.

Nuclease that resolves Holliday junction intermediates in genetic recombination.

Acetoacetyl-CoA Synthetase (AACS) is a novel cytosolic ketone body (acetoacetate)-specific ligase.

The lysozyme 2 gene is a member of a family of lysozyme-like genes.

PPT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells with C-10xHis. The accession number is O88531.

CES1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family.

Please enquire for more information about Glucosyltransferase201-freeze dried including the price, delivery time and more detailed product information at the technical inquiry form on this page

CYB5R1 Protein, Human, Recombinant (His) is expressed in E.

OXA-11 is a β-lactamase enzyme, which is a type of protein produced by certain bacteria. These enzymes are derived from the bacterial source and are responsible for antibiotic resistance. The primary mode of action of OXA-11 is the hydrolysis of the β-lactam ring found in various antibiotics, such as penicillins and cephalosporins, rendering them ineffective. This enzymatic activity allows bacteria to survive exposure to these antimicrobial agents, posing a significant challenge in clinical settings. The study of OXA-11 is crucial for understanding and counteracting antibiotic resistance. It provides insights into the mechanisms by which bacteria adapt to antibiotic pressure, informing the development of novel antimicrobial therapies and inhibitors that can circumvent the action of such enzymes. Research into OXA-11 and other related β-lactamases is a vital part of ongoing efforts to combat the growing problem of antibiotic-resistant bacterial infections, contributing to the development of more effective treatment strategies.

VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family.

B3GAT3, encoding beta-1,3-glucuronyltransferase 3, has an important role in proteoglycan biosynthesis.

Biotinidase, also known as biotinase and BTD, is a ubiquitous mammalian cell enzyme which expressed at high levels in the liver, serum, and kidney.

Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (

Putative phospholipase.

Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions.

Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for

PLA2G5 Protein, Mouse, Recombinant (His & SUMO) is expressed in E.

Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-

kynureninase/KYNU Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

RAC1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli with N-10xHis. The accession number is P63000.

UBE2D3 Protein, Human, Recombinant (His & SUMO) is expressed in E.

Collagenase is an enzymes that is responsible for breaking peptide bonds in collagen

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers.

Hydrolyzes sphingomyelin in addition to phosphatidylcholine.

ENPP7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Endopeptidase, liquid, food grade is an enzymatic product that functions as a crucial component in the hydrolysis of protein substrates. This enzyme is typically derived from microbial sources, such as bacteria or fungi, and is cultivated under controlled fermentation processes to ensure high purity and activity levels. The primary mode of action of endopeptidases involves the cleavage of peptide bonds within protein molecules, effectively breaking down long protein chains into smaller peptides and amino acids. In food processing, this enzyme is widely utilized for various applications, including tenderizing meat, enhancing flavors, and improving the digestibility of protein-rich products. Its use in dairy processing, for example, aids in the production of certain cheeses by accelerating protein breakdown, which is essential for texture and flavor development. In brewing, endopeptidases contribute to the clarity and stability of the final product by reducing protein haze. Due to its specificity and efficiency, Endopeptidase, liquid, food grade is integral in optimizing processes in the food industry, allowing for greater control over product characteristics and quality.

ENPP3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Aconitase 2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells.

Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family.

NAALADL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron

TrkB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

N/A.

RET Protein, Human, Recombinant (aa 658-1114, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Applications Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Necrostatin-1 is an inhibitor of RIP1 kinase that prevents the death of TNF-α-treated FADD-deficient Jurkat cells. Necrostatin-1 has been used to investigate the pathological importance of necroptosis in ischemic brain injury and myocardial infarction. References Foresti, R., et al: J. Biol. Chem., 272, 18411 (1997); Cardenas, A., et al.: J. Neurochem., 74, 2041 (2000); Degterev, et al.: Nat. Chem. Biol., 1, 112 (2005); Hitomi, J., et al.: Cell, 135, 1311 (2008);

Carboxypeptidase D Protein, Human, Recombinant (hFc & Myc) is expressed in HEK293 mammalian cells with C-hFC-Myc tag.

Adenylate Kinase 1 Protein, Human, Recombinant (His) is expressed in E.

CKMT1A belongs to the ATP:guanido phosphotransferase family.

N/A.

ACP5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Fructose-6-phosphate kinase (Phosphofructokinase, PFK, EC 2.7.1.11) is an enzyme that catalyzes the following reaction:  F6P + ATP ⇌ F1,6BP + ATP  One unit of PFK will convert 1.0 μmole of fructose 6-phosphate and ATP to fructose 1,6-diphosphate and ADP per minute at pH 9.0 at 30 °C.

Oxalate Oxidase, freeze-dried, from Wheat is an enzyme preparation which is derived from wheat and functions through the oxidative degradation of oxalate. This enzyme catalyzes the conversion of oxalate into carbon dioxide and hydrogen peroxide, utilizing oxygen as a co-substrate in the process. The activity of Oxalate Oxidase is crucial in biological and biochemical applications where oxalate degradation is required. This enzyme is commonly applied in the analysis of oxalate levels in various biological specimens, facilitating research in fields such as plant pathology and clinical diagnostics. In plants, Oxalate Oxidase contributes to resistance against pathogens by generating hydrogen peroxide, a reactive oxygen species that plays a role in defense mechanisms. In clinical settings, it aids in the study of hyperoxaluria, a condition characterized by excessive oxalate excretion. The ability of Oxalate Oxidase to effectively break down oxalate without side reactions makes it valuable in these contexts, offering precise and reliable results for scientific investigations.

Glucosyltransferase (GTase) is the enzyme that transfers glucose to another organic molecule (aglycon), establishing glycosidic linkage. UDP-glucose dependent GTases are part of the enzyme family of glucosyltransferases, they are versatile tools in glucosylation reactions. Different GTases have different substrate specificities. For the specificity of GT206 Glucosyltransferase, please see Table 1 that lists the available GTases with GT206 highlighted.Color: beigeForm: lyophilisateProtein content: 0.5 mg/mgThe glucosyltransferase was tested in a glucosylation reaction of a preferred substrate. High conversion after up to 24 h reaction time was observed. Not sure which GTase to choose? Consider our Glucosyltransferase kit, which contains all 8 Glucosyltransferases.

Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide.

N/A.

Plays a key role in glycolysis and gluconeogenesis.

G3BP1 Protein, Human, Recombinant (His) is expressed in E. coli.

Ubiquitin-conjugating enzyme E2 A (also known as HHR6A or UBE2A), encoded by human DNA repair genes HHR6A, belongs to the ubiquitin-conjugating enzymes (E2

Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.

Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.

LacBuster™-S 1000 is an enzymatic product derived from microbial sources, specifically engineered for precision and efficiency. It is a beta-lactamase, which catalyzes the hydrolysis of the beta-lactam ring found in beta-lactam antibiotics such as penicillins and cephalosporins, rendering them inactive. The enzyme achieves this by breaking the amide bond within the beta-lactam ring, a critical structural component necessary for antibiotic activity. LacBuster™-S 1000 is utilized in various applications where neutralization of beta-lactam antibiotics is required. Its primary use is in the pharmaceutical industry for the detoxification of waste streams contaminated with beta-lactam substances, thereby preventing the potential impact on environmental microbiota. Additionally, in research settings, it is employed to study antibiotic resistance mechanisms and to control antibiotic effects in microbiological assays. This enzyme must be handled with precision to ensure effective application, given its specific activity and role in deactivating antibiotics.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

Alpha Amylase (Amylase, α-Amylase, 1,4-α-D-glucan glucanohydrolase, glycogenase, systematic name 4-α-D-glucan glucanohydrolase; EC 3.2.1.1, CAS Number [9000-90-2]) is an enzyme that catalyses hydrolysis of large polysacharides into smaller fragments. Alpha amylase targets alpha bonds of 1→4 glycosidic linkages of poly- and oligosaccharides with three or more D-glucose units. One unit of Alpha Amylase will catalyze the hydrolysis of 1.0 μmol of 2-chloro-4-nitrophenyl-α-D-maltotrioside to yield 2-chloro-4-nitrophenol per minute at 37°C. Human pancreatic Alpha Amylase is supplied as clear, colorless to light yellow liquid solution at ≥400U/mL, specific activity ≥100 U/mg protein.Store at 2-8 °C on arrival.

N/A.

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a

N/A.

Copper-containing enzyme that catalyzes the first step in the synthesis of melanin

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative

β-galactosidase is an exoglycosidase which hydrolyzes the β-glycosidic bond formed between a galactose and its organic moiety.

FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD).

PPP1CB Protein, Human, Recombinant (His) is expressed in E. coli.

Tyrosine Hydroxylase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Carboxypeptidase Y (EC 3.4.16.1) is an exopeptidase enzyme. It hydrolyzes peptide bonds of C-terminal residues and it remains active in the presence of urea at low to moderate concentrations. One unit of the Carboxypeptidase Y will hydrolyze 1.0 μmole of a chromogenic peptide substrate, releasing C-terminal alanine and generating a light-absorbing product. Carboxypeptidase Y has been obtained from yeast S. cerevisiae, has a broad substrate specificity and can therefore be used in sequence analysis of proteins. Carboxypeptidase Y has a temperature optimum in the 20 - 30 °C range and pH optimum between pH 6 and 7.

Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.

Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

MCAT Protein, S.

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell

ALAS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E.

β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate.

Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion

Protein arginine methyltransferase 3, also known as PRMT3, is one of four type I protein arginine methyltransferases (PRMT) that in humans is encoded by the

RET Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.