NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
Produits appartenant à la catégorie "NF-κB"
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Tyrosol
CAS :Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present mostFormule :C8H10O2Degré de pureté :100% - 99.28%Couleur et forme :SolidMasse moléculaire :138.16Astaxanthin
CAS :Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Formule :C40H52O4Degré de pureté :95.1% - 99.79%Couleur et forme :Needles From Acetone/Light Petroleum SolidMasse moléculaire :596.84TRAF-STOP inhibitor 6877002
CAS :TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.Formule :C17H17NODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :251.32Handelin
CAS :Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.Formule :C32H40O8Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :552.66RIPK2-IN-3
CAS :RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.Formule :C25H22N4O2Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :410.47GSK2983559 free acid
CAS :GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.Formule :C21H23N4O7PS2Degré de pureté :97.87% - 98.61%Couleur et forme :SolidMasse moléculaire :538.53Narasin (sodium salt)
CAS :Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells andFormule :C43H71NaO11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :787.01Oditrasertib
CAS :Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.Formule :C14H15F2N3O2Degré de pureté :98.65% - 99.65%Couleur et forme :SolidMasse moléculaire :295.28Naringin dihydrochalcone
CAS :Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.Formule :C27H34O14Degré de pureté :99.07% - 99.16%Couleur et forme :Solid PowderMasse moléculaire :582.55Isodeoxyelephantopin
CAS :Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formule :C19H20O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :344.36NIK SMI1
CAS :NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).Formule :C20H19N3O4Degré de pureté :99.04% - 99.99%Couleur et forme :SolidMasse moléculaire :365.38Ref: TM-T16290
1mg87,00€5mg183,00€10mg296,00€25mg593,00€50mg932,00€100mg1.501,00€200mg2.052,00€1mL*10mM (DMSO)432,00€NDMC101
CAS :NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.Formule :C13H9ClFNO2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :265.67MRT67307
CAS :Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formule :C26H36N6O2Degré de pureté :99.25% - 99.79%Couleur et forme :SolidMasse moléculaire :464.6GSK481
CAS :GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.Formule :C21H19N3O4Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :377.39COX-2-IN-48
COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.Couleur et forme :Odour SolidCOX-2-IN-32
CAS :COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.Formule :C25H24O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.45Methylthiouracil
CAS :Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.Formule :C5H6N2OSDegré de pureté :100% - 99.89%Couleur et forme :Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Masse moléculaire :142.18α-Lipoic Acid
CAS :α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in dietary supplements.Formule :C8H14O2S2Degré de pureté :98.39% - 99.73%Couleur et forme :Forms Yellowish Flakes Light Yellow To Yellow PowderMasse moléculaire :206.33Shikonin
CAS :Shikonin: TMEM16A inhibitor (IC50: 6.5μM), targets PKM2, suppresses NF-κB, inhibits TNF-α, and reduces exosome secretion.Formule :C16H16O5Degré de pureté :98.13% - 99.9%Couleur et forme :SolidMasse moléculaire :288.3Ref: TM-T1125
5mg34,00€10mg52,00€25mg87,00€50mg140,00€100mg215,00€200mg319,00€500mg533,00€1mL*10mM (DMSO)52,00€20(S)-Ginsenoside Rg3
CAS :20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formule :C42H72O13Degré de pureté :100% - 99.93%Couleur et forme :SolidMasse moléculaire :785.01
