Nrf2
Nrf2 est un facteur de transcription qui régule l'expression des protéines antioxydantes et des enzymes de détoxification, jouant un rôle crucial dans la défense cellulaire contre le stress oxydatif et l'inflammation. L'activation de la signalisation Nrf2 offre une protection contre diverses maladies, notamment le cancer, la neurodégénérescence et les troubles cardiovasculaires. Les modulateurs de Nrf2 sont explorés pour leurs potentielles applications thérapeutiques dans la réduction des dommages oxydatifs et de l'inflammation. Chez CymitQuimica, nous offrons une gamme de modulateurs de la voie Nrf2 de haute qualité pour soutenir vos recherches sur le stress oxydatif, l'inflammation et la prévention des maladies.
Produits appartenant à la catégorie "Nrf2"
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35 produits dans cette catégorie.
NK-252
CAS :NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential.Formule :C13H11N5O3Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :285.26KI696
CAS :KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Formule :C28H30N4O6SDegré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :550.63Ref: TM-T11758L
1mg144,00€5mg350,00€10mg558,00€25mg1.026,00€50mg1.406,00€100mg1.872,00€1mL*10mM (DMSO)449,00€Anti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Degré de pureté :>95%Couleur et forme :Odour LiquidML162
CAS :ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formule :C23H22Cl2N2O3SDegré de pureté :98.42% - 99.78%Couleur et forme :SolidMasse moléculaire :477.4NSC23925
CAS :NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Formule :C22H26Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.36Rehmapicrogenin
CAS :Rehmapicrogenin regulates the Nrf2/ARE signaling pathway. Nrf2/ARE signaling pathway is the most important pathway of oxidative stress.Formule :C10H16O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :184.23Kinsenoside
CAS :Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formule :C10H16O8Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :264.23VVD-130037
CAS :VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Formule :C17H17ClN4O2Degré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :344.8CDDO-EA
CAS :CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.Formule :C33H46N2O3Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :518.73Ref: TM-T10733
1mg85,00€5mg169,00€10mg298,00€25mg512,00€50mg732,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)187,00€Ezetimibe
CAS :Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formule :C24H21F2NO3Degré de pureté :97.28% - 99.97%Couleur et forme :SolidMasse moléculaire :409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€(E/Z)-BCI
CAS :(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFormule :C22H23NODegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :317.42Ref: TM-T11139
1mg80,00€5mg155,00€10mg283,00€25mg452,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)170,00€4-Octyl itaconate
CAS :4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.Formule :C13H22O4Degré de pureté :99.3% - 99.94%Couleur et forme :SolidMasse moléculaire :242.31CPUY192018
CAS :CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions, and can be used to study mitochondrial autophagy.Formule :C28H26N2O10S2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :614.64TAT 14
CAS :TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Formule :C137H230N48O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3173.59ML334
CAS :ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Formule :C26H26N2O5Degré de pureté :98.06% - 98.06%Couleur et forme :SolidMasse moléculaire :446.49CBR-470-1
CAS :CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.Formule :C14H20ClNO4S2Degré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :365.9RA-839
CAS :RA-839 is a Keap1 conjugate and Nrf2 signaling activator, and an inhibitor of Keap1/Nrf2 interaction with anticancer activity.Formule :C25H28N2O4SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :452.57Gingerenone A
CAS :Gingerenone A, an Nrf2-Gpx4 activator isolated from ginger, has anticancer activity and inhibits iron death in mice with colitis secondary to liver injury (SLI)Formule :C21H24O5Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :356.41Nrf2 activator-1
CAS :Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Formule :C30H34N4O6SDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :578.68KI696 isomer
CAS :KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Formule :C28H30N4O6SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :550.63Ref: TM-T11758
1mg154,00€5mg464,00€10mg777,00€25mg1.568,00€50mg2.110,00€100mg2.783,00€1mL*10mM (DMSO)510,00€Brusatol
CAS :Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Formule :C26H32O11Degré de pureté :99.35% - 99.82%Couleur et forme :SolidMasse moléculaire :520.53Ref: TM-TQ0211
1mg39,00€5mg94,00€10mg160,00€25mg311,00€50mg502,00€100mg715,00€200mg938,00€1mL*10mM (DMSO)107,00€DDO-7263
CAS :DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.Formule :C14H9F2N3ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :273.24Nrf2-IN-3
CAS :Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.Formule :C22H26N4O4SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :442.53Ref: TM-T78841
1mg65,00€5mg139,00€10mg217,00€25mg411,00€50mg658,00€100mg1.035,00€200mg1.396,00€1mL*10mM (DMSO)154,00€4-P-PDOT
CAS :4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Formule :C19H21NODegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :279.38Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Couleur et forme :Odour Liquid(E)-[6]-Dehydroparadol
CAS :(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.Formule :C17H24O3Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :276.37Ref: TM-T13436
1mg44,00€5mg93,00€10mg116,00€25mg207,00€50mg283,00€100mg406,00€500mg919,00€1mL*10mM (DMSO)93,00€AEM1
CAS :AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.Formule :C20H14FN3O2SDegré de pureté :98.37%Couleur et forme :SolidMasse moléculaire :379.41Ref: TM-T8979
2mg38,00€5mg51,00€10mg92,00€25mg170,00€50mg298,00€100mg510,00€200mg737,00€1mL*10mM (DMSO)60,00€Nrf2-IN-1
CAS :Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).Formule :C21H22ClN3O2Degré de pureté :95.00% - 99.68%Couleur et forme :SolidMasse moléculaire :383.87Ref: TM-T12253
1mg78,00€5mg169,00€10mg230,00€25mg383,00€50mg537,00€100mg748,00€200mg1.035,00€1mL*10mM (DMSO)301,00€AA147
CAS :AA147 is an ER proteostasis regulator that selectively activates the ATF6 arm of UPR as a prodrug.Formule :C16H17NO2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :255.31Ref: TM-T14080
5mg63,00€10mg96,00€25mg178,00€50mg265,00€100mg395,00€500mg894,00€1mL*10mM (DMSO)69,00€Anti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Couleur et forme :Odour LiquidK67
CAS :K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.Formule :C29H30N2O7S2Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :582.69Eriodictyol-7-O-glucoside
CAS :Eriodictyol-7-O-glucoside, a flavonoid in pistachio skin, activates Nrf2 and protects against Cisplatin toxicity.Formule :C21H22O11Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :450.39Trilobatin
CAS :Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormule :C21H24O10Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :436.41Ref: TM-T2S0731
1mg64,00€5mg124,00€10mg165,00€25mg323,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)137,00€Artemisitene
CAS :Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Formule :C15H20O5Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :280.32Ref: TM-T21065
1mg95,00€5mg187,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)281,00€I-152
CAS :Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Formule :C9H16N2O3S2Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :264.37
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