
mAPK p38
Les p38 MAPK sont un sous-groupe de MAPK qui répondent aux signaux de stress et sont impliqués dans la régulation de l'inflammation, de la différenciation cellulaire, de l'apoptose et de l'autophagie. La signalisation p38 MAPK est cruciale dans les réponses immunitaires et est impliquée dans diverses maladies, y compris les affections inflammatoires chroniques, le cancer et les troubles neurodégénératifs. Chez CymitQuimica, nous proposons une gamme complète d'inhibiteurs et de modulateurs de p38 MAPK pour soutenir vos recherches sur l'inflammation, la réponse au stress et le développement thérapeutique.
Produits appartenant à la catégorie "mAPK p38"
Trier par
Paris saponin VII
CAS :Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formule :C51H82O21Degré de pureté :99.51% - 99.63%Couleur et forme :SolidMasse moléculaire :1031.18VX-702
CAS :VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formule :C19H12F4N4O2Degré de pureté :100% - 99%Couleur et forme :SolidMasse moléculaire :404.32Emprumapimod
CAS :Emprumapimod, an oral p38α MAPK inhibitor, targets RPMI-8226 cells, curbs LPS-induced IL-6; IC50: 100 pM; for cardiomyopathy, acute pain.Formule :C24H29F2N5O3Degré de pureté :100% - 99.21%Couleur et forme :SolidMasse moléculaire :473.52MAPK13-IN-1
CAS :MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).Formule :C20H23N5O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :365.43Ref: TM-T11943
1mg99,00€2mg144,00€5mg235,00€10mg354,00€25mg610,00€50mg885,00€100mg1.293,00€500mg2.585,00€1mL*10mM (DMSO)259,00€Afatinib Dimaleate
CAS :Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formule :C32H33ClFN5O11Degré de pureté :100% - 98.11%Couleur et forme :SolidMasse moléculaire :718.08Ref: TM-T1773
1g467,00€5mg40,00€10mg59,00€25mg87,00€50mg107,00€100mg140,00€200mg188,00€500mg313,00€1mL*10mM (DMSO)66,00€(S)-(-)-PH-797804
CAS :Produit contrôléFormule :C19H38N5O5Couleur et forme :NeatMasse moléculaire :416.536Afatinib
CAS :Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formule :C24H25ClFN5O3Degré de pureté :97.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Ref: TM-T21312
5mg35,00€10mg51,00€25mg86,00€50mg115,00€100mg144,00€200mg177,00€500mg300,00€1mL*10mM (DMSO)52,00€Nitidine chloride
CAS :1.Formule :C21H18ClNO4Degré de pureté :96.59% - 98.91%Couleur et forme :SolidMasse moléculaire :383.82BI-3406
CAS :BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Formule :C23H25F3N4O3Degré de pureté :99.20% - 99.66%Couleur et forme :SolidMasse moléculaire :462.46Ref: TM-T12979
1mg73,00€5mg160,00€10mg250,00€25mg464,00€50mg663,00€100mg919,00€500mg1.833,00€1mL*10mM (DMSO)170,00€AMG 900
CAS :AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formule :C28H21N7OSDegré de pureté :98.35% - 98.9%Couleur et forme :SolidMasse moléculaire :503.58Ref: TM-T6380
1mg52,00€5mg97,00€10mg166,00€25mg303,00€50mg467,00€100mg682,00€500mg1.415,00€1mL*10mM (DMSO)105,00€Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity.Formule :C38H56N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.86SB 202190 hydrochloride
CAS :SB 202190 hydrochloride is a p38 MAPK inhibitor that inhibits p38α and p38β2 with selective, cell-permeable, and antitumor ,differentiation to cardiomyocytes.Formule :C20H15ClFN3ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :367.8Ref: TM-T35592
2mg49,00€5mg66,00€10mg90,00€25mg145,00€50mg207,00€100mg309,00€200mg459,00€1mL*10mM (DMSO)71,00€Dehydrocorydaline chloride
CAS :Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formule :C22H24ClNO4Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :401.88Ref: TM-T10990
1mg58,00€5mg111,00€10mg160,00€25mg264,00€50mg396,00€100mg563,00€1mL*10mM (DMSO)124,00€PDE4-IN-26
PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.Formule :C22H18F2N4O3SCouleur et forme :SolidMasse moléculaire :456.47Wortmannin
CAS :Produit contrôléApplications Wortmannin is a phosphatidylinositol 3 kinase (PI3K) inhibitor. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Liberman R., et. al.: J. Biol. Chem., 289, 1355 (2014)Formule :C23H24O8Couleur et forme :White To Light YellowMasse moléculaire :428.43PS-166276
CAS :PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of 28 nM against p38 kinase and an IC50 of 170 nM in the THP-1 TNFα assay.Formule :C20H30N8OCouleur et forme :SolidMasse moléculaire :398.51p38α inhibitor 4
CAS :p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.Formule :C14H7F6N3ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :347.215AZD7624
CAS :AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formule :C27H30FN5O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :491.56Ref: TM-T14381
1mg73,00€5mg160,00€10mg250,00€25mg507,00€50mg737,00€100mg1.026,00€1mL*10mM (DMSO)170,00€OVA-E1 peptide TFA
CAS :OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.Formule :C49H77F3N10O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1119.19