PDE
Les phosphodiestérases (PDE) sont des enzymes qui hydrolysent les nucléotides cycliques, tels que l'AMPc et le GMPc, en leurs formes inactives, jouant un rôle clé dans la régulation des voies de signalisation intracellulaire. Les inhibiteurs de PDE sont utilisés dans le traitement de diverses affections, notamment les maladies cardiovasculaires, la dysfonction érectile et les troubles respiratoires, en raison de leur capacité à moduler les niveaux de nucléotides cycliques. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs de PDE pour soutenir vos recherches en signalisation cellulaire, pharmacologie et développement thérapeutique.
Produits appartenant à la catégorie "PDE"
Trier par
Propentofylline
CAS :Propentofylline (Hextol) has neuroprotective, antiproliferative and anti-inflammatory activities and can be used in the study of Alzheimer's disease.Formule :C15H22N4O3Degré de pureté :99.11% - 99.42%Couleur et forme :Off-White SolidMasse moléculaire :306.36Ref: TM-T19812
1mg69,00€5mg145,00€10mg212,00€25mg358,00€50mg527,00€100mg750,00€1mL*10mM (DMSO)157,00€cis-Tadalafil
CAS :Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.Formule :C22H19N3O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :389.4Anti-ALDH7A1 Antibody (3P955)
Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.Couleur et forme :Odour LiquidThioquinapiperifil dihydrochloride
CAS :Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.Formule :C24H29ClN6OSDegré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :485.05Ref: TM-T9773
1mg84,00€5mg178,00€10mg266,00€25mg434,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)205,00€Homo Sildenafil
CAS :Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.Formule :C23H32N6O4SDegré de pureté :99.88%Couleur et forme :White SolidMasse moléculaire :488.6Ref: TM-T8919
2mg42,00€5mg64,00€10mg92,00€25mg187,00€50mg281,00€100mg393,00€200mg552,00€1mL*10mM (DMSO)78,00€Ketotifen fumarate
CAS :Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.Formule :C23H23NO5SDegré de pureté :99.25% - 99.73%Couleur et forme :SolidMasse moléculaire :425.5Mardepodect
CAS :Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE.Formule :C25H20N4ODegré de pureté :98.82% - 99.81%Couleur et forme :SolidMasse moléculaire :392.45Ref: TM-T16499
1mg43,00€2mg55,00€5mg92,00€10mg150,00€25mg245,00€50mg365,00€100mg547,00€1mL*10mM (DMSO)92,00€Lirimilast
CAS :Lirimilast: oral PDE4 inhibitor (IC50: 49 nM), anti-inflammatory, treats asthma/COPD.Formule :C17H12Cl2N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.26PDE10-IN-1
CAS :PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.Formule :C21H19N7Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :369.42N-Methylbenzamide
CAS :N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.Formule :C8H9NODegré de pureté :99.83%Couleur et forme :Physical Description Off-White Crystalline Solid (Ntp 1992)Masse moléculaire :135.16Anti-ALDH7A1 Antibody (5P692)
Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.Couleur et forme :Odour LiquidBAY 73-6691
CAS :BAY 73-6691 is an inhibitor of brain penetrant PDE9A.Formule :C15H12ClF3N4OCouleur et forme :SolidMasse moléculaire :356.73Dasantafil
CAS :Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Formule :C22H28BrN5O5Degré de pureté :98.64% - 99.16%Couleur et forme :SolidMasse moléculaire :522.39Amino Tadalafil
CAS :Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.Formule :C21H18N4O4Degré de pureté :99.45%Couleur et forme :White PowderMasse moléculaire :390.39TyK2-IN-2
CAS :TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formule :C16H18N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.35ATX inhibitor 1
CAS :ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).Formule :C21H23Cl2N2O6PDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :501.3PF-8380
CAS :PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).Formule :C22H21Cl2N3O5Degré de pureté :98.70% - 99.25%Couleur et forme :SolidMasse moléculaire :478.33Vardenafil
CAS :Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction.Formule :C23H32N6O4SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :488.6Nauclefine
CAS :Nauclefine, a plant alkaloid, triggers cancer cell death through PDE3A-SLFN12, binding but not inhibiting PDE3A.Formule :C18H13N3ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :287.32BAY 73-6691 racemate
CAS :BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.Formule :C15H12ClF3N4OCouleur et forme :SolidMasse moléculaire :356.73Autotaxin-IN-1
CAS :Autotaxin-IN-1: strong inhibitor for osteoarthritis pain; IC50=2.2 nM; good PK and PK/PD.Formule :C21H23N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.45NSP-805
CAS :NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.Formule :C17H19N3O2Degré de pureté :99.10%Couleur et forme :SolidMasse moléculaire :297.35Ref: TM-T12267
1mg52,00€5mg116,00€10mg187,00€25mg325,00€50mg467,00€100mg645,00€200mg872,00€1mL*10mM (DMSO)128,00€MK-8189
CAS :MK-8189 is a potent and selective pyrimidine PDE10A inhibitor, with excellent PDE (phosphodiesterase) selectivity for the treatment of schizophrenia.Formule :C19H22N6OSDegré de pureté :100% - 99.67%Couleur et forme :SolidMasse moléculaire :382.48Tovinontrine
CAS :Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.Formule :C21H26N6O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :394.47FCPR03
CAS :FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.Formule :C15H19F2NO3Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :299.31Ref: TM-T39341
1mg52,00€2mg75,00€5mg116,00€10mg183,00€25mg311,00€50mg444,00€100mg605,00€200mg815,00€1mL*10mM (DMSO)128,00€T-0156
CAS :T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4.Formule :C31H29N5O7Degré de pureté :100% - 98.42%Couleur et forme :SoildMasse moléculaire :583.59Deltasonamide 2
CAS :Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.Formule :C30H39ClN6O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :647.25Imazodan
CAS :Imazodan is a compound with positive inotropic activity and is a type III phosphodiesterase inhibitor that can be used to study heart failure.Formule :C13H12N4ODegré de pureté :98.56% - 99.36%Couleur et forme :SolidMasse moléculaire :240.26Imazodan hydrochloride
CAS :Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure.Formule :C13H13ClN4ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :276.72Roflumilast
CAS :Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potentialFormule :C17H14Cl2F2N2O3Degré de pureté :100.00% - 99.76%Couleur et forme :SolidMasse moléculaire :403.21BRL-50481
CAS :BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.Formule :C9H12N2O4SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :244.27Autotaxin-IN-3
CAS :Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.Formule :C22H21N9O2Degré de pureté :98.49% - 99.21%Couleur et forme :SolidMasse moléculaire :443.46Ref: TM-T10415
2mg46,00€5mg70,00€10mg101,00€25mg183,00€50mg284,00€100mg455,00€200mg625,00€1mL*10mM (DMSO)78,00€GEBR-7b
CAS :GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.Formule :C13H16O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :220.26PDE5-IN-2
CAS :PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)Formule :C25H21N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :491.52Gisadenafil
CAS :Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.Formule :C23H33N7O5SDegré de pureté :98.25% - 99.06%Couleur et forme :SolidMasse moléculaire :519.62Ref: TM-T15381
1mg185,00€5mg415,00€10mg613,00€25mg938,00€50mg1.311,00€100mg1.768,00€1mL*10mM (DMSO)520,00€Pumafentrine
CAS :Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.Formule :C29H39N3O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :477.64PF-05085727
CAS :PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.Formule :C20H18F3N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.4OPC18750 HCl
CAS :OPC18750 HCl is a phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.Formule :C20H23ClN2O4Degré de pureté :98.92%Couleur et forme :SoildMasse moléculaire :390.86Ref: TM-T83974
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€1mL*10mM (DMSO)47,00€[11C]MP 10
CAS :[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.Formule :C25H20N4ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :391.45YM976
CAS :YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)Formule :C17H16ClN3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :313.78PF-00489791
CAS :PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.Formule :C20H28N8O4SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :476.55K134
CAS :K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.Formule :C22H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.48WAY127093B racemate
CAS :WAY127093B racemate is the racemate of WAY127093B. WAY127093B is a phosphodiesterase IV inhibitor with oral activity in rats and guinea pigs.Formule :C23H28N4O4Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :424.49Ref: TM-T13331
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg475,00€100mg638,00€200mg845,00€1mL*10mM (DMSO)170,00€Avanafil
CAS :Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.Formule :C23H26ClN7O3Degré de pureté :98% - 99.03%Couleur et forme :White SolidMasse moléculaire :483.95Cilomilast
CAS :Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.Formule :C20H25NO4Degré de pureté :97.37% - 99.43%Couleur et forme :White SolidMasse moléculaire :343.42PF-04957325
CAS :PF-04957325 is an inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A.PF-04957325 can be used for the study of autoimmune encephalomyelitis.Formule :C14H15F3N8OSDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :400.38Ref: TM-T12422
1mg137,00€5mg235,00€10mg354,00€25mg610,00€50mg885,00€100mg1.320,00€1mL*10mM (DMSO)207,00€MR-L2
CAS :MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Formule :C19H16Cl3FN4ODegré de pureté :98.09% - 98.94%Couleur et forme :SolidMasse moléculaire :441.71Ref: TM-T12103
1mg145,00€2mg207,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€500mg3.125,00€1mL*10mM (DMSO)378,00€AMG 579
CAS :AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).Formule :C25H23N5O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :441.48Ref: TM-T14217
1mg35,00€2mg47,00€5mg73,00€10mg105,00€25mgÀ demander50mgÀ demander1mL*10mM (DMSO)82,00€Vardenafil hydrochloride trihydrate
CAS :Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.Formule :C23H32N6O4S·HCl·3H2ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :579.11Ref: TM-T4097
5mg47,00€10mg70,00€25mg125,00€50mg187,00€100mg298,00€200mg444,00€500mg715,00€1mL*10mM (DMSO)63,00€Enpp-1-IN-1
CAS :Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)Formule :C17H17N3O3SDegré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :343.4Ref: TM-T7888
1mg133,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€1mL*10mM (DMSO)303,00€N-Ethyl tadalafil
CAS :N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.Formule :C23H21N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :403.43BI 1015550
CAS :Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM.Cost-effective and quality-assured.Formule :C20H25ClN6O2SDegré de pureté :100% - 99.71%Couleur et forme :SoildMasse moléculaire :448.97Deltasonamide 2 (TFA)
CAS :Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.Formule :C32H40ClF3N6O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :761.28Carbodenafil
CAS :Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).Formule :C24H32N6O3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :452.55Autotaxin-IN-5
CAS :Autotaxin-IN-5 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.Formule :C30H29N9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.61Enpp/Carbonic anhydrase-IN-1
CAS :Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase.Formule :C23H25NO4SDegré de pureté :100%Couleur et forme :SoildMasse moléculaire :411.51GSK356278
CAS :GSK356278: selective PDE4A/B/D inhibitor, pIC50~8.7, anti-inflammatory, anxiolytic, cognition-enhancing.Formule :C21H25N7O2SDegré de pureté :99.43% - 99.79%Couleur et forme :SolidMasse moléculaire :439.53CP671305
CAS :CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.Formule :C23H19FN2O7Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :454.42,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide
CAS :2,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide is a PDE inhibitor.Formule :C9H9Cl2F2NO3SDegré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :320.14Ref: TM-T50062
1mg84,00€2mg111,00€5mg172,00€10mg249,00€25mg426,00€50mg627,00€100mg893,00€1mL*10mM (DMSO)172,00€ent-Tadalafil
CAS :ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).Formule :C22H19N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.4Ro 20-1724
CAS :Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1Formule :C15H22N2O3Degré de pureté :98% - 99.14%Couleur et forme :SolidMasse moléculaire :278.35Deltarasin
CAS :Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formule :C40H37N5ODegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :603.75SEP-0372814
CAS :SEP-0372814 is a potent inhibitor of PDE10.Formule :C21H19N7Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :369.42BC 11-38
CAS :BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).Formule :C15H16N2OS2Degré de pureté :97.71% - 98.72%Couleur et forme :SolidMasse moléculaire :304.43Ref: TM-T21865
1mg35,00€5mg70,00€10mg97,00€25mg202,00€50mg329,00€100mg527,00€200mg747,00€1mL*10mM (DMSO)81,00€Zardaverine
CAS :Zardaverine (BY 290) is a PDE3/4 inhibitor with anti-hepatocarcinogenic activity and is used in the study of acute renal failure and chronic airflow obstructionFormule :C12H10F2N2O3Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :268.22WAY-313170
CAS :WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.Formule :C19H17ClN2O2S2Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :404.93RS-25344 hydrochloride
CAS :RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFormule :C19H14ClN5O4Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :411.8Ref: TM-T23256
2mg34,00€5mg52,00€10mg85,00€25mg170,00€50mg259,00€100mg374,00€200mg545,00€1mL*10mM (DMSO)65,00€ITI-214
CAS :ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits potent PDE1 inhibitory activity.Formule :C29H29FN7O5PDegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :605.56Ref: TM-T11689
1mg74,00€2mg97,00€5mg166,00€10mg303,00€25mg533,00€50mg750,00€100mg1.064,00€1mL*10mM (DMSO)217,00€PF-05180999
CAS :α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.Formule :C19H17F3N8Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :414.39Ziritaxestat
CAS :Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.Formule :C30H33FN8O2SDegré de pureté :97% - 99.85%Couleur et forme :SolidMasse moléculaire :588.7UK 227786
CAS :UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.Formule :C22H22Cl2N4O4Degré de pureté :100%Couleur et forme :SoildMasse moléculaire :477.34Ref: TM-T11220L
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)304,00€Arofylline
CAS :Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.Formule :C14H13ClN4O2Degré de pureté :97.98%Couleur et forme :SolidMasse moléculaire :304.73Verofylline
CAS :Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for theFormule :C12H18N4O2Degré de pureté :97.97% - 99.55%Couleur et forme :SolidMasse moléculaire :250.3Siguazodan
CAS :Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM.Formule :C14H16N6ODegré de pureté :99.63% - 99.77%Couleur et forme :SolidMasse moléculaire :284.32Ref: TM-T12913
1mg42,00€5mg88,00€10mg127,00€25mg264,00€50mg424,00€100mg655,00€200mg924,00€1mL*10mM (DMSO)87,00€GSK256066 Trifluoroacetate
CAS :GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.Formule :C29H27F3N4O7SCouleur et forme :SolidMasse moléculaire :632.61THPP-1
CAS :THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).Formule :C23H21ClN6O3Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :464.9CI-1044
CAS :CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).Formule :C23H19N5O2Couleur et forme :SolidMasse moléculaire :397.43Anti-ALDH7A1 Antibody-FITC (5P692)
Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.Couleur et forme :Odour LiquidML-030
CAS :ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.Formule :C20H20N4O4SDegré de pureté :97.93%Couleur et forme :SolidMasse moléculaire :412.46Nortadalafil
CAS :Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.Formule :C21H17N3O4Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :375.38Ref: TM-T6147
1mg37,00€2mg52,00€5mg79,00€10mg111,00€25mg202,00€50mg354,00€100mg567,00€200mg805,00€500mg1.198,00€1mL*10mM (DMSO)87,00€Olprinone
CAS :Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuateFormule :C14H10N4ODegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :250.26Dovramilast
CAS :Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.Formule :C24H28N2O6SDegré de pureté :98.75% - 99.74%Couleur et forme :SolidMasse moléculaire :472.55Anagrelide
CAS :Anagrelide (Xagrid) is a Platelet-reducing Agent.Formule :C10H7Cl2N3ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :256.09Balipodect
CAS :Balipodect (TAK063) is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its selectivity is >15000-fold over other PDEs.Formule :C23H17FN6O2Degré de pureté :98.32% - 98.97%Couleur et forme :SolidMasse moléculaire :428.42Ref: TM-T1745
1mg38,00€2mg49,00€5mg79,00€10mg93,00€25mg156,00€50mg256,00€100mg444,00€1mL*10mM (DMSO)79,00€TPN171
CAS :TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonaryFormule :C24H35N5O3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :441.57PQ-10
CAS :PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.Formule :C22H21N5O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :403.43Ref: TM-T24656
2mg34,00€5mg52,00€10mg85,00€25mg170,00€50mg259,00€100mg374,00€200mg545,00€1mL*10mM (DMSO)57,00€Mirodenafil dihydrochloride
CAS :Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formule :C26H39Cl2N5O5SDegré de pureté :99.64% - 99.78%Couleur et forme :SolidMasse moléculaire :604.59Bay 60-7550
CAS :Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.Formule :C27H32N4O4Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :476.57ENPP1 Inhibitor C
CAS :ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.Formule :C15H18N6Couleur et forme :SolidMasse moléculaire :282.34Vardenafil dihydrochloride
CAS :Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.Formule :C23H34Cl2N6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :561.52Enoximone
CAS :Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Formule :C12H12N2O2SDegré de pureté :95.52%Couleur et forme :SolidMasse moléculaire :248.3KD-027
CAS :KD-027 is a novel and long-acting PDE5A(phosphodiesterase 5A) inhibitor with potential antihypertensive activity.Formule :C25H35N7O6SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :561.65MY-5445
CAS :MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).Formule :C20H14ClN3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :331.8BW-A 78U
CAS :BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.Formule :C13H12FN5Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :257.27Ref: TM-T5101
1mg39,00€5mg101,00€10mg153,00€25mg249,00€50mg359,00€100mg507,00€200mg695,00€1mL*10mM (DMSO)44,00€Piclamilast
CAS :Piclamilast (RP 73401) is a PDE4 inhibitor.Formule :C18H18Cl2N2O3Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :381.25Filaminast
CAS :Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.Formule :C15H20N2O4Degré de pureté :98.44% - 99.64%Couleur et forme :SolidMasse moléculaire :292.33Ref: TM-T31792
1mg226,00€5mg552,00€10mg735,00€25mg1.111,00€50mg1.491,00€100mg2.005,00€200mg2.707,00€1mL*10mM (DMSO)500,00€Senazodan hydrochloride
CAS :Senazodan hydrochloride (Senazodan HCl) is a Ca2+ sensitizer and phosphodiesterase 3 (PDE3) inhibitor used in the study of cardiovascular diseases.Formule :C15H15ClN4ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :302.76Ensifentrine
CAS :Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), thatFormule :C26H31N5O4Degré de pureté :98.45% - 99.94%Couleur et forme :SolidMasse moléculaire :477.56Ref: TM-T25376
1mg35,00€5mg96,00€10mg160,00€25mg329,00€50mg533,00€100mg847,00€200mg1.159,00€1mL*10mM (DMSO)105,00€Lodenafil
CAS :Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)Formule :C23H32N6O5SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :504.6Ref: TM-T7346
2mg35,00€5mg50,00€10mg81,00€25mg129,00€50mg187,00€100mg259,00€200mg373,00€1mL*10mM (DMSO)56,00€BAY 2666605
CAS :BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.Formule :C17H12F4N2O2Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :352.28Ref: TM-T9805
1mg97,00€5mg235,00€10mg376,00€25mg828,00€50mg1.320,00€100mg2.118,00€1mL*10mM (DMSO)259,00€
![[11C]MP 10](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT6042.webp&w=3840&q=75)
