Facteur Xa
Le facteur Xa est une enzyme cruciale dans la cascade de coagulation qui convertit la prothrombine en thrombine, entraînant la formation de caillots sanguins. L'inhibition du facteur Xa est une stratégie thérapeutique largement utilisée pour prévenir et traiter les troubles thromboemboliques, tels que la thrombose veineuse profonde, l'embolie pulmonaire et l'AVC. Chez CymitQuimica, nous proposons des inhibiteurs du facteur Xa pour soutenir vos recherches en hématologie, santé cardiovasculaire et thérapie anticoagulante.
Produits appartenant à la catégorie "Facteur Xa"
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43 produits dans cette catégorie.
Edoxaban
CAS :Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.Formule :C24H30ClN7O4SDegré de pureté :99.6% - 99.71%Couleur et forme :SolidMasse moléculaire :548.06Rivaroxaban
CAS :Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Formule :C19H18ClN3O5SDegré de pureté :100% - 99.93%Couleur et forme :SolidMasse moléculaire :435.88Ref: TM-T1184
2mg39,00€5mg57,00€10mg79,00€25mg95,00€50mg118,00€100mg178,00€200mg269,00€500mg455,00€1mL*10mM (DMSO)63,00€FXIa-IN-15
CAS :FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.Formule :C32H23ClF3N7O4Couleur et forme :SolidMasse moléculaire :662.02Gabexate mesylate
CAS :Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Formule :C17H27N3O7SDegré de pureté :99.2% - 99.64%Couleur et forme :White CrystalMasse moléculaire :417.48Lofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Couleur et forme :Odour LiquidFrunexian
CAS :Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.Formule :C19H26N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.43Dechloro Rivaroxaban
CAS :Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.Formule :C19H19N3O5SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :401.44Ref: TM-T78215
2mg37,00€5mg52,00€10mg88,00€25mg154,00€50mg235,00€100mg376,00€500mg1.017,00€1mL*10mM (DMSO)58,00€2-Methoxyphenothiazine
CAS :2-Methoxy Phenothiazine is light yellow or light gray solid.Formule :C13H11NOSDegré de pureté :99.56%Couleur et forme :Orange Yellow Crystal PowderMasse moléculaire :229.3Abelacimab
CAS :NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.Degré de pureté :95% - 95%Couleur et forme :LiquidOtamixaban
CAS :Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.Formule :C25H26N4O4Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :446.5Rat Factor Xa
RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.Couleur et forme :Odour SolidFXIa-IN-7
CAS :FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.Formule :C28H28N2O4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :456.53Fidexaban
CAS :Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assaysFormule :C25H24F2N6O5Degré de pureté :98.08% - 99.42%Couleur et forme :SolidMasse moléculaire :526.49Canine Factor Xa
CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.Couleur et forme :Odour SolidCH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS :CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].Formule :C27H42N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.67Rabbit Factor Xa
RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.Couleur et forme :Odour Solid4-Chlorophenylurea
CAS :4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.Formule :C7H7ClN2ODegré de pureté :98.69%Couleur et forme :White Granular / PrillMasse moléculaire :170.6Garadacimab
CAS :Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :146.5 kDaD-Pro-Phe-Arg-Chloromethylketone
CAS :D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammationFormule :C21H31ClN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.96Eribaxaban
CAS :Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.Formule :C24H22ClFN4O4Degré de pureté :98.96% - 99.74%Couleur et forme :SolidMasse moléculaire :484.91Betrixaban maleate
CAS :"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."Formule :C27H26ClN5O7Degré de pureté :99.46% - 99.86%Couleur et forme :SolidMasse moléculaire :567.98cMCoFx1
CAS :cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formule :C146H232N52O44S6Couleur et forme :SolidMasse moléculaire :3612.12Betrixaban
CAS :Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.Formule :C23H22ClN5O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :451.91Ref: TM-T4341
2mg47,00€5mg70,00€10mg96,00€25mg167,00€50mg283,00€100mg454,00€500mg998,00€1mL*10mM (DMSO)77,00€Denecimig
CAS :Denecimig (Mim8) is a bispecific and humanized IgG4κ antibody, hemophilia A, activated coagulation factors IXa (FIXa) and X (FX) arresting bleeding.Degré de pureté :95%Couleur et forme :LiquidHeparin sodium salt
CAS :Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Formule :C26H42N2NaO37S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1157.89Coumarin
CAS :Coumarin: plant-based poison found in tonka beans, woodruff, bison grass; used to make anticoagulants like warfarin.Formule :C9H6O2Degré de pureté :98.89%Couleur et forme :White Solid CrystallineMasse moléculaire :146.14Rivaroxaban-d4
CAS :Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.Formule :C19H18ClN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.91Betrixaban hydrochloride(330942-05-7(free base))
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Formule :C23H23Cl2N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :488.36Ref: TM-T4690
1mg48,00€2mg60,00€5mg97,00€10mg154,00€25mg338,00€50mg520,00€100mg748,00€1mL*10mM (DMSO)106,00€Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS :Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.Formule :C27H28N4O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :488.54Zifaxaban
CAS :Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.Formule :C20H16ClN3O4SDegré de pureté :97.46% - 99.42%Couleur et forme :SolidMasse moléculaire :429.88Ref: TM-T29215
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formule :C24H22N5NaO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.52Darexaban
CAS :Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Formule :C27H30N4O4Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :474.55Ref: TM-T31206
1mg48,00€5mg95,00€10mg144,00€25mg235,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)92,00€Benzamidine hydrochloride
CAS :Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Formule :C7H9ClN2Degré de pureté :99.25% - 99.97%Couleur et forme :White To Off-White PowderMasse moléculaire :156.61Letaxaban
CAS :Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.Formule :C22H26ClN3O5SDegré de pureté :98.68% - 99.01%Couleur et forme :SolidMasse moléculaire :479.98Enoxaparin sodium
CAS :Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formule :C42H59N3Na4O35S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1322Edoxaban Tosylate Monohydrate
CAS :Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formule :C31H40ClN7O8S2Degré de pureté :99.86% - 99.91%Couleur et forme :SolidMasse moléculaire :738.27EMD-503982
CAS :EMD-503982 is a potential Factor Xa and Factor VIIa inhibitor with anticancer activity for the study of thromboembolic and neurologic diseases.Formule :C22H23ClN4O5Degré de pureté :98.44% - 99.12%Couleur et forme :SolidMasse moléculaire :458.90Apixaban
CAS :Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Formule :C25H25N5O4Degré de pureté :99.73% - 99.93%Couleur et forme :SolidMasse moléculaire :459.5Asundexian
CAS :Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formule :C26H21ClF4N6O4Degré de pureté :100% - 99.90%Couleur et forme :SolidMasse moléculaire :592.935-R-Rivaroxaban
CAS :5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.Formule :C19H18ClN3O5SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :435.88RWJ-445167
CAS :RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Formule :C18H24N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49LY 517717
CAS :LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).Formule :C27H33N5O2Degré de pureté :99.42% - 99.88%Couleur et forme :SolidMasse moléculaire :459.58Fondaparinux sodium
CAS :Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Formule :C31H44N3Na10O49S8Degré de pureté :100.00% - ≥98%Couleur et forme :SolidMasse moléculaire :1729.09
