Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
Produits appartenant à la catégorie "Anhydrase carbonique"
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Carbonic anhydrase inhibitor 15
Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].Formule :C27H33N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.71SH7s
SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.Formule :C24H19ClF3N5O4SCouleur et forme :SolidMasse moléculaire :565.95Polmacoxib
CAS :Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.Formule :C18H16FNO4SDegré de pureté :97.88%Couleur et forme :SolidMasse moléculaire :361.39Ref: TM-T21294
2mg47,00€5mg70,00€10mg107,00€25mg173,00€50mg259,00€100mg378,00€200mg563,00€1mL*10mM (DMSO)77,00€ALP/Carbonic anhydrase-IN-1
CAS :Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkalineFormule :C15H16N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.3CAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Formule :C23H21N5O3SCouleur et forme :SolidMasse moléculaire :447.51CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Couleur et forme :Odour SolidWES-1
CAS :WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,Formule :C20H20N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.46Zonisamide
CAS :Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Formule :C8H8N2O3SDegré de pureté :99.05% - 99.9%Couleur et forme :Off-White PowderMasse moléculaire :212.23hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formule :C22H20N4O6S2Masse moléculaire :500.547Chlorothiazide
CAS :Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formule :C7H6ClN3O4S2Degré de pureté :95.42%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72hCAII-IN-9
CAS :hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.Formule :C15H16ClN3O5S2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :417.89Carbonic anhydrase inhibitor 12
CAS :CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.Formule :C27H22BrN5O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :640.53CA Ⅱ-IN-1
CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.Formule :C18H19NO6SCouleur et forme :SolidMasse moléculaire :377.41U-104
CAS :U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).Formule :C13H12FN3O3SDegré de pureté :100% - 99.6%Couleur et forme :SolidMasse moléculaire :309.32Ref: TM-T2017
5mg35,00€10mg52,00€25mg87,00€50mg142,00€100mg250,00€200mg399,00€500mg652,00€1mL*10mM (DMSO)58,00€Dichlorphenamide
CAS :Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.Formule :C6H6Cl2N2O4S2Degré de pureté :96.87% - 98.51%Couleur et forme :Needles From Dimethylsulfoxide + Water SolidMasse moléculaire :305.16Ref: TM-T6469
5mg50,00€10mg65,00€25mg87,00€50mg96,00€100mg140,00€200mg202,00€500mg340,00€1mL*10mM (DMSO)59,00€CAIX Inhibitor S4
CAS :CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.Formule :C15H17N3O4SDegré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :335.38Ref: TM-T36758
2mg40,00€5mg60,00€10mg96,00€25mg188,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)66,00€EMAC10101d
CAS :compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with anFormule :C17H15Cl2N3O2S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :428.36hCAI/II/IV-IN-28
CAS :hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.Formule :C14H15N3O3SDegré de pureté :96.48%Couleur et forme :SolidMasse moléculaire :305.35Carbonic anhydrase inhibitor 26
Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.Formule :C17H14N6O4Couleur et forme :SolidMasse moléculaire :366.33Perfluorohexane sulfonamide
CAS :Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.Formule :C6H2F13NO2SCouleur et forme :SolidMasse moléculaire :399.13Tioxolone
CAS :Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Formule :C7H4O3SDegré de pureté :97.79%Couleur et forme :Light Yellow To Beige PowderMasse moléculaire :168.172,3-dihydro-1H-indene-5-sulfonamide
CAS :2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.Formule :C9H11NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :197.25Ref: TM-T8611
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)149,00€hCAIX-IN-16
CAS :hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Formule :C20H20N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Formule :C16H14F3N3O4SCouleur et forme :SolidMasse moléculaire :401.36Disulfamide
CAS :Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.Formule :C7H9ClN2O4S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :284.74hCA/VEGFR-2-IN-1
hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (Formule :C21H17FN6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.46Methyclothiazide
CAS :Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions includingFormule :C9H11Cl2N3O4S2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :360.24hCAIX/VII-IN-1
hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.Formule :C16H13BFN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.1Brinzolamide
CAS :Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Formule :C12H21N3O5S3Degré de pureté :100% - 99.84%Couleur et forme :Crystalline SolidMasse moléculaire :383.51AChE/CA I-IN-1
AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.Formule :C14H19NO6SCouleur et forme :SolidMasse moléculaire :329.37Methazolamide
CAS :Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Formule :C5H8N4O3S2Degré de pureté :98.45% - 99.77%Couleur et forme :Crystals From Water SolidMasse moléculaire :236.27Carbonic anhydrase
CAS :Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.Couleur et forme :SolidIndisulam
CAS :Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formule :C14H12ClN3O4S2Degré de pureté :98.68% - 99.77%Couleur et forme :SolidMasse moléculaire :385.85Ref: TM-T4321
1mg35,00€2mg46,00€5mg66,00€10mg93,00€25mg137,00€50mg210,00€100mg314,00€1mL*10mM (DMSO)72,00€AV22-149
AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .Formule :C23H28F3N3O6S2Couleur et forme :SolidMasse moléculaire :563.61Dorzolamide hydrochloride
CAS :Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme thatFormule :C10H17ClN2O4S3Degré de pureté :99.48% - 99.67%Couleur et forme :White Off-White Crystalline PowderMasse moléculaire :360.9hCAXII-IN-7
hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.Formule :C26H25N5O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :567.64Topiramate
CAS :Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formule :C12H21NO8SDegré de pureté :99.79% - 99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :339.36Orthanilamide
CAS :Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formule :C6H8N2O2SDegré de pureté :99.27% - 99.96%Couleur et forme :White To Pale Cream Crystalline Powder Or CrystalsMasse moléculaire :172.2Acetazolamide sodium
CAS :Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.Formule :C4H5N4NaO3S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :244.23hBChE-IN-3
hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.Couleur et forme :Odour SolidCompound CDy9
CAS :Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Formule :C15H16N2O5SDegré de pureté :99.75%Couleur et forme :SoildMasse moléculaire :336.36Ref: TM-T67774
2mg38,00€5mg58,00€10mg96,00€25mg170,00€50mg253,00€100mg364,00€200mg512,00€1mL*10mM (DMSO)71,00€Benzolamide
CAS :Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.Formule :C8H8N4O4S3Degré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :320.37Ref: TM-T23782
5mg51,00€10mg88,00€25mg160,00€50mg235,00€100mg349,00€200mg515,00€1mL*10mM (DMSO)57,00€α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formule :C25H22N6OS2Couleur et forme :SolidMasse moléculaire :486.614-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS :4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-Formule :C7H8F3N3O4S2Degré de pureté :98.58%Couleur et forme :SolidMasse moléculaire :319.28Sultiame
CAS :Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.Formule :C10H14N2O4S2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :290.36Cyclamic acid sodium
CAS :Sodium cyclamate is a carbonic anhydrase inhibitor, artificial sweetener, with anticonvulsant properties, and used in cancer research.Formule :C6H12NNaO3SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :201.22hCAI/II-IN-6
CAS :hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).Formule :C19H24N4O3SDegré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :388.48hCAIX-IN-15
CAS :hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormule :C18H14FN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.41hCAIX/XII-IN-8
CAS :hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Formule :C16H13Cl2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.28Benzthiazide
CAS :Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.Formule :C15H14ClN3O4S3Degré de pureté :100% - 99.79%Couleur et forme :Crystals From Acetone SolidMasse moléculaire :431.94
