Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
Produits appartenant à la catégorie "Anhydrase carbonique"
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hCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFormule :C17H14N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.4CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Formule :C19H16ClN3O5S2Masse moléculaire :465.93Histone acetyltransferase p300 Inhibitor 4c
CAS :2-Amino-4-(4-chlorophenyl)thiazole blocks hCA I/II, AChE, BChE with Ki: ~0.008, 0.124, 0.129, 0.083 µM.Formule :C9H7ClN2SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :210.68pNNP
CAS :pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Formule :C6H6NO6PDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :219.09Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Couleur et forme :Lyophilized PowderMasse moléculaire :32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Benzenesulfonamide
CAS :Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formule :C6H7NO2SDegré de pureté :99.42% - 99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :157.19Acetazolamide
CAS :Acetazolamide (Diamox) is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of acetazolamide is Sulfonamides.Formule :C4H6N4O3S2Degré de pureté :99.61% - 99.94%Couleur et forme :Crystals From Water 1992)Masse moléculaire :222.245hCA XII-IN-6
Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferativeFormule :C11H9N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.35CA inhibitor 2
Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].Formule :C7H9N7O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.39Carbonic anhydrase inhibitor 6
CAS :Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.Formule :C26H25N3O5SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :491.56hCAIX-IN-5
CAS :hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.Formule :C18H12FNO3Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :309.29Fluorometholone Acetate
CAS :Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.Formule :C24H31FO5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :418.5Carbonic anhydrase inhibitor 16
CAS :Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.Formule :C14H10N2O4SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :302.31hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formule :C23H22N4O7S2Masse moléculaire :530.573Dimethylfraxetin
CAS :Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)Formule :C12H12O5Degré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :236.22BChE-IN-36
hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.Couleur et forme :Odour SolidEthoxzolamide
CAS :Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.Formule :C9H10N2O3S2Degré de pureté :96.33% - 99.62%Couleur et forme :Crystals From Ethyl Acetate + Skellysolve B SolidMasse moléculaire :258.32
